DK3153169T3 - Fremgangsmåde til behandling af tumor, farmaceutisk sammensætning og medicinæskesæt - Google Patents

Fremgangsmåde til behandling af tumor, farmaceutisk sammensætning og medicinæskesæt Download PDF

Info

Publication number
DK3153169T3
DK3153169T3 DK15803424.9T DK15803424T DK3153169T3 DK 3153169 T3 DK3153169 T3 DK 3153169T3 DK 15803424 T DK15803424 T DK 15803424T DK 3153169 T3 DK3153169 T3 DK 3153169T3
Authority
DK
Denmark
Prior art keywords
tumor
treatment
pharmaceutical composition
medicine box
box set
Prior art date
Application number
DK15803424.9T
Other languages
English (en)
Inventor
Shanchun Wang
Xunqiang Wang
Hongmei Gu
Ping Dong
Hongjiang Xu
Original Assignee
Chia Tai Tianqing Pharmaceutical Group Co Ltd
Advenchen Laboratories Nanjing Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chia Tai Tianqing Pharmaceutical Group Co Ltd, Advenchen Laboratories Nanjing Ltd filed Critical Chia Tai Tianqing Pharmaceutical Group Co Ltd
Application granted granted Critical
Publication of DK3153169T3 publication Critical patent/DK3153169T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • External Artificial Organs (AREA)
DK15803424.9T 2014-06-06 2015-06-05 Fremgangsmåde til behandling af tumor, farmaceutisk sammensætning og medicinæskesæt DK3153169T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201410250113.7A CN105311030B (zh) 2014-06-06 2014-06-06 用于抗肿瘤的螺取代化合物
PCT/CN2015/080863 WO2015185012A1 (zh) 2014-06-06 2015-06-05 用于治疗肿瘤的方法、药物组合物和药盒套件

Publications (1)

Publication Number Publication Date
DK3153169T3 true DK3153169T3 (da) 2020-11-02

Family

ID=54766182

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15803424.9T DK3153169T3 (da) 2014-06-06 2015-06-05 Fremgangsmåde til behandling af tumor, farmaceutisk sammensætning og medicinæskesæt

Country Status (13)

Country Link
US (2) US10251876B2 (da)
EP (1) EP3153169B1 (da)
JP (1) JP6508544B2 (da)
CN (3) CN105311030B (da)
DK (1) DK3153169T3 (da)
ES (1) ES2828177T3 (da)
HK (1) HK1231377A1 (da)
HR (1) HRP20201737T1 (da)
HU (1) HUE051707T2 (da)
PL (1) PL3153169T3 (da)
RS (1) RS60990B1 (da)
SI (1) SI3153169T1 (da)
WO (2) WO2015185013A1 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105311030B (zh) 2014-06-06 2020-03-24 正大天晴药业集团股份有限公司 用于抗肿瘤的螺取代化合物
CN105311029A (zh) 2014-06-06 2016-02-10 正大天晴药业集团股份有限公司 抗肿瘤活性的喹啉衍生物
CA2954999C (en) 2014-07-14 2020-01-07 Advenchen Pharmaceuticals, Nanjing Ltd. Fused quinoline compounds as pi3k, mtor inhibitors
EP3231797B1 (en) * 2014-12-09 2020-02-26 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Quinoline derivative against non-small cell lung cancer
US9751859B2 (en) * 2015-05-04 2017-09-05 Advenchen Pharmaceuticals, LLC Process for preparing an anti-cancer agent, 1-((4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)methyl)cyclopropanamine, its crystalline form and its salts
AU2016293841B2 (en) 2015-07-11 2020-10-08 Advenchen Pharmaceuticals, LLC Fused quinoline compunds as pi3k/mTor inhibitors
CN107296811B (zh) 2016-04-15 2022-12-30 正大天晴药业集团股份有限公司 一种用于治疗胃癌的喹啉衍生物
CN110650741A (zh) * 2017-05-26 2020-01-03 正大天晴药业集团股份有限公司 用于治疗结直肠癌的喹啉衍生物
EP3682883A4 (en) * 2017-09-15 2021-06-02 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. CHINOLINE DERIVATIVE FOR THE TREATMENT OF NEUROENDOCRINE TUMORS
CN107970241B (zh) * 2018-01-22 2020-05-22 正大天晴药业集团股份有限公司 一种新型酪氨酸激酶抑制剂安罗替尼在制备抑制骨肉瘤的药物中的应用
AU2019227391B2 (en) 2018-03-02 2024-06-13 Advenchen Laboratories Nanjing Ltd. Crystal of compound as c-Met kinase inhibitor and preparation method therefor and use thereof
US11554115B2 (en) 2018-03-14 2023-01-17 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Quinoline derivative for treatment of triple-negative breast cancer
US11419862B2 (en) 2018-03-14 2022-08-23 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Quinoline derivative for treatment of nasopharyngeal carcinoma
JP7270633B2 (ja) * 2018-03-14 2023-05-10 チア タイ ティエンチン ファーマシューティカル グループ カンパニー リミテッド 上咽頭がん治療用キノリン誘導体
CN117085017A (zh) * 2018-09-18 2023-11-21 正大天晴药业集团股份有限公司 用于治疗小细胞肺癌的喹啉衍生物
CN111110681A (zh) * 2018-10-31 2020-05-08 正大天晴药业集团股份有限公司 喹啉衍生物联合卡培他滨在治疗肝癌的用途
CN109748904A (zh) * 2019-01-31 2019-05-14 正大天晴药业集团股份有限公司 喹啉衍生物的结晶
US20220193067A1 (en) * 2019-04-19 2022-06-23 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Quinoline compound or pharmaceutically acceptable salt thereof for treating ewing's sarcoma
AU2020273687A1 (en) * 2019-05-10 2022-01-06 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Quinoline derivative used for soft tissue sarcoma combination therapy
JP2022533211A (ja) * 2019-05-20 2022-07-21 チア タイ ティエンチン ファーマシューティカル グループ カンパニー リミテッド 小細胞肺がんの併用療法用キノリン誘導体
CN112043831A (zh) * 2019-06-05 2020-12-08 正大天晴药业集团股份有限公司 用于联合治疗乳腺癌的喹啉类化合物
CA3222537A1 (en) * 2021-05-14 2022-11-17 Nanjing Chuangte Pharmaceutical Technology Co., Ltd Pharmaceutical formulations
WO2024002147A1 (zh) * 2022-06-29 2024-01-04 正大天晴药业集团股份有限公司 喹啉衍生物或其盐环糊精包合物

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0510390D0 (en) 2005-05-20 2005-06-29 Novartis Ag Organic compounds
JP2010519309A (ja) 2007-02-20 2010-06-03 ノバルティス アーゲー 脂質キナーゼおよびｍＴＯＲのデュアル阻害剤としてのイミダゾキノリン
US8163923B2 (en) 2007-03-14 2012-04-24 Advenchen Laboratories, Llc Spiro substituted compounds as angiogenesis inhibitors
US8148532B2 (en) 2007-03-14 2012-04-03 Guoqing Paul Chen Spiro substituted compounds as angiogenesis inhibitors
US20080229184A1 (en) * 2007-03-15 2008-09-18 Microsoft Corporation Private sheets in shared spreadsheets
WO2009155527A2 (en) 2008-06-19 2009-12-23 Progenics Pharmaceuticals, Inc. Phosphatidylinositol 3 kinase inhibitors
IT1393351B1 (it) 2009-03-16 2012-04-20 Eos Ethical Oncology Science Spa In Forma Abbreviata Eos Spa Procedimento per la preparazione della 6-(7-((1-amminociclopropil)metossi)-6-metossichinolin-4-ilossi)-n-metil-1-naftammide e suoi intermedi di sintesi
JP6076737B2 (ja) * 2009-06-12 2017-02-08 ジェネレックス ファーマシューティカルズ インコーポレイテッド 高血圧症の防止及び治療のための組成物並びに方法
CN102344438B (zh) * 2010-08-01 2014-02-19 正大天晴药业集团股份有限公司 喹啉衍生物的结晶及其制备方法
KR101721739B1 (ko) 2011-11-14 2017-03-30 치아타이 티안큉 파마수티컬 그룹 주식회사 키나제 조절 화합물, 이를 함유하는 조성물 및 그의 용도
EA201591205A1 (ru) 2013-01-18 2015-12-30 Адвенчен Фармасьютикалс, Ллс Способ получения противоопухолевого агента 6-(7-((1-аминоциклопропил)-метокси)-6-метоксихинолин-4-илокси)-n-метил-1-нафтамида и его кристаллической структуры
CN103127024B (zh) * 2013-03-12 2014-10-15 成都天台山制药有限公司 稳定的三磷酸腺苷二钠片剂
CN104513229A (zh) 2013-09-28 2015-04-15 正大天晴药业集团股份有限公司 喹唑啉衍生物及其制备方法
CN105311030B (zh) 2014-06-06 2020-03-24 正大天晴药业集团股份有限公司 用于抗肿瘤的螺取代化合物
CN105311029A (zh) 2014-06-06 2016-02-10 正大天晴药业集团股份有限公司 抗肿瘤活性的喹啉衍生物
CA2954999C (en) 2014-07-14 2020-01-07 Advenchen Pharmaceuticals, Nanjing Ltd. Fused quinoline compounds as pi3k, mtor inhibitors
EP3231797B1 (en) * 2014-12-09 2020-02-26 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Quinoline derivative against non-small cell lung cancer
US9751859B2 (en) 2015-05-04 2017-09-05 Advenchen Pharmaceuticals, LLC Process for preparing an anti-cancer agent, 1-((4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)methyl)cyclopropanamine, its crystalline form and its salts

Also Published As

Publication number Publication date
WO2015185013A1 (zh) 2015-12-10
EP3153169B1 (en) 2020-08-05
EP3153169A4 (en) 2018-01-10
SI3153169T1 (sl) 2021-01-29
US10251876B2 (en) 2019-04-09
CN105311030A (zh) 2016-02-10
JP6508544B2 (ja) 2019-05-08
RS60990B1 (sr) 2020-11-30
US20190269671A1 (en) 2019-09-05
ES2828177T3 (es) 2021-05-25
CN106456625A (zh) 2017-02-22
US20170182027A1 (en) 2017-06-29
HK1231377A1 (zh) 2017-12-22
JP2017527524A (ja) 2017-09-21
WO2015185012A1 (zh) 2015-12-10
CN112076192A (zh) 2020-12-15
PL3153169T3 (pl) 2021-04-06
HRP20201737T1 (hr) 2021-03-19
HUE051707T2 (hu) 2021-03-29
CN105311030B (zh) 2020-03-24
EP3153169A1 (en) 2017-04-12

Similar Documents

Publication Publication Date Title
DK3153169T3 (da) Fremgangsmåde til behandling af tumor, farmaceutisk sammensætning og medicinæskesæt
DK3453707T3 (da) Benzazepinderivat, fremgangsmåde til fremstilling, farmaceutisk sammensætning og anvendelse deraf
DK3616720T3 (da) Farmaceutisk sammensætning til cancerbehandling
DK3386484T3 (da) Sammensætninger og fremgangsmåder til afgivelse af terapeutiske midler
DK3102673T3 (da) Fremgangsmåder og sammensætninger til behandling af beta-talassæmi
DK3643709T3 (da) Isoindolinderivat, mellemprodukt, fremgangsmåde til fremstilling, farmaceutisk sammensætning og anvendelse deraf
DK3212233T3 (da) Kombinationsterapi til behandling af sygdom
DK3326641T3 (da) Rna-holdig sammensætning til behandling af tumorsygdomme
DK3378859T3 (da) Benzofuranderivater, fremgangsmåde til fremstilling deraf og anvendelse deraf i medicin
DK3354282T3 (da) Glycan-terapeutiske midler og relaterede fremgangsmåder deraf
DK3265043T3 (da) Hjælpemiddel til patienttransport og -træning
DK3204386T3 (da) Substituerede aminopurinforbindelser, sammensætninger deraf og fremgangsmåder til behandling dermed
DK3240612T3 (da) Fremgangsmåder til behandling af nethindesygdomme
BR112016027041A2 (pt) Combinações farmacêuticas para tratamento do câncer
DK3102200T3 (da) Terapeutisk forbindelse og sammensætning
DK3209696T3 (da) Fremgangsmåder og sammensætninger til diagnosticering og behandling af glioblastom
DK3183010T3 (da) Anordning og tilhørende fremgangsmåde til behandling af medicinsk affald
DK3200815T3 (da) Fremgangsmåder og sammensætninger til behandling af cancer
DK3189074T3 (da) Sammensætninger og metoder til behandling og forebyggelse af inflammation
DK3277295T3 (da) Sammensætning til behandling af en patogen, metabolisk tarmmikrobiotatilstand og afledte sygdomme
DK3094640T3 (da) Fremgangsmåder til steril kromatografi og fremstilling
DK3110446T3 (da) Fremgangsmåder og sammensætninger til behandling af Siglec-8-associerede sygdomme
DK3142664T3 (da) Sammensætninger og fremgangsmåder til behandling og diagnosticering af øjensygdomme
DK3380525T3 (da) Farmaceutiske formuleringer og fremgangsmåder til anvendelse deraf
DK3468604T3 (da) Farmaceutiske kombinationer til behandling af cancer