DK2190426T3 - Griseofulvin-analoger til behandling af cancer ved hæmning af centrosomal clusterdannelse - Google Patents

Griseofulvin-analoger til behandling af cancer ved hæmning af centrosomal clusterdannelse

Info

Publication number
DK2190426T3
DK2190426T3 DK08761406.1T DK08761406T DK2190426T3 DK 2190426 T3 DK2190426 T3 DK 2190426T3 DK 08761406 T DK08761406 T DK 08761406T DK 2190426 T3 DK2190426 T3 DK 2190426T3
Authority
DK
Denmark
Prior art keywords
griseofulvine
analogs
inhibition
cancer treatment
cluster formation
Prior art date
Application number
DK08761406.1T
Other languages
English (en)
Inventor
Mads Hartvig Clausen
Alwin Kraemer
Blanka Rebacz
Thomas Ostenfeld Larsen
Original Assignee
Dkfz Krebsforschungszentrum
Univ Denmark Tech Dtu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dkfz Krebsforschungszentrum, Univ Denmark Tech Dtu filed Critical Dkfz Krebsforschungszentrum
Application granted granted Critical
Publication of DK2190426T3 publication Critical patent/DK2190426T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK08761406.1T 2007-06-28 2008-06-30 Griseofulvin-analoger til behandling af cancer ved hæmning af centrosomal clusterdannelse DK2190426T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07111335A EP2008652A1 (en) 2007-06-28 2007-06-28 Griseofulvin analogues for the treatment of cancer by inhibition of centrosomal clustering
PCT/EP2008/058410 WO2009000937A1 (en) 2007-06-28 2008-06-30 Griseofulvin analogues for the treatment of cancer by inhibition of centrosomal clustering

Publications (1)

Publication Number Publication Date
DK2190426T3 true DK2190426T3 (da) 2012-03-26

Family

ID=38667076

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08761406.1T DK2190426T3 (da) 2007-06-28 2008-06-30 Griseofulvin-analoger til behandling af cancer ved hæmning af centrosomal clusterdannelse

Country Status (6)

Country Link
US (1) US20110178170A1 (da)
EP (2) EP2008652A1 (da)
AT (1) ATE543494T1 (da)
DK (1) DK2190426T3 (da)
ES (1) ES2381057T3 (da)
WO (1) WO2009000937A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2204367A1 (en) * 2008-12-22 2010-07-07 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Griseofulvin analogues for the treatment of cancer by inhibition of centrosomal clustering
US9416143B2 (en) 2012-08-01 2016-08-16 Pierre Fabre Medicament Griseofulvin derivatives
CN103058971B (zh) * 2013-01-17 2014-08-06 福州大学 一种源于棘孢曲霉的苯醌螺环化合物及其应用
CN104860909B (zh) * 2015-04-09 2017-03-08 西北农林科技大学 灰黄霉素衍生物、灰黄霉素及其衍生物的抗菌活性应用
HUE058182T2 (hu) 2016-03-30 2022-07-28 Daiichi Sankyo Co Ltd Grizeofulvin vegyület
TWI811243B (zh) 2017-09-29 2023-08-11 日商第一三共股份有限公司 灰黃黴素化合物及醫藥用途
KR102125005B1 (ko) * 2017-10-27 2020-06-22 한양대학교 에리카산학협력단 53bp1의 신규한 용도
CN108484552B (zh) * 2018-06-15 2020-03-10 河南大学 一种多取代3-苯并呋喃酮螺环己烯衍生物及其制备方法
CN108823110B (zh) * 2018-07-26 2021-07-16 福州工微生物科技有限公司 一株产灰黄霉素的菌株及其应用
CN112080438B (zh) * 2020-10-15 2023-05-12 内蒙古格林特制药有限责任公司 一种灰黄霉素低产沫菌种及低产沫菌种的制备方法和应用
CN116076510B (zh) * 2022-05-30 2024-10-29 河南大学 多取代3-苯并呋喃酮螺环己烯衍生物作为杀菌剂在防治植物病菌中的应用
CN116199657A (zh) * 2023-02-20 2023-06-02 延安大学 灰黄霉素4位醚化衍生物及其应用
CN117229246B (zh) * 2023-05-23 2024-06-07 湖北天勤生物科技股份有限公司 具有抗炎活性的化合物及其制备方法和用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL324905A1 (en) * 1995-08-03 1998-06-22 Procter & Gamble Application of griseofulvin in carcinoma development inhibition

Also Published As

Publication number Publication date
EP2008652A1 (en) 2008-12-31
ES2381057T3 (es) 2012-05-22
ATE543494T1 (de) 2012-02-15
WO2009000937A1 (en) 2008-12-31
EP2190426A1 (en) 2010-06-02
US20110178170A1 (en) 2011-07-21
EP2190426B1 (en) 2012-02-01

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