DK154082C - METHOD OF ANALOGUE FOR THE PREPARATION OF 4-AMINO-6,7-DIMETHOXY-2- (PIPERAZIN-1-YL OR HOMOPIPERAZIN-1-YL) -QUINAZOLINE COMPOUNDS OR PHARMACEUTICAL ACCEPTABLE ACID ADDITIONAL SALTS - Google Patents

METHOD OF ANALOGUE FOR THE PREPARATION OF 4-AMINO-6,7-DIMETHOXY-2- (PIPERAZIN-1-YL OR HOMOPIPERAZIN-1-YL) -QUINAZOLINE COMPOUNDS OR PHARMACEUTICAL ACCEPTABLE ACID ADDITIONAL SALTS

Info

Publication number: DK154082C
Authority: DK; Denmark
Prior art keywords: homopiperazin; piperazin; dimethoxy; analogue; amino
Prior art date: 1977-11-05

Application number

DK428678A

Other languages

Danish (da)

Other versions

DK428678A (en

DK154082B (en

Inventor

Simon Fraser Campbell

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-11-05

Filing date

1978-09-27

Publication date

1989-02-27

1978-09-27 Application filed by Pfizer filed Critical Pfizer

1978-10-18 Priority to US05/952,317 priority Critical patent/US4188390A/en

1979-05-06 Publication of DK428678A publication Critical patent/DK428678A/en

1988-10-10 Publication of DK154082B publication Critical patent/DK154082B/en

1989-02-27 Application granted granted Critical

1989-02-27 Publication of DK154082C publication Critical patent/DK154082C/en

1992-03-16 Priority to BG096072A priority patent/BG60337B2/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

DK428678A 1977-11-05 1978-09-27 METHOD OF ANALOGUE FOR THE PREPARATION OF 4-AMINO-6,7-DIMETHOXY-2- (PIPERAZIN-1-YL OR HOMOPIPERAZIN-1-YL) -QUINAZOLINE COMPOUNDS OR PHARMACEUTICAL ACCEPTABLE ACID ADDITIONAL SALTS DK154082C (en)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
US05/952,317 US4188390A (en)	1977-11-05	1978-10-18	Antihypertensive 4-amino-2-[4-(1,4-benzodioxan-2-carbonyl) piperazin-1-yl or homopiperazin-1-yl]quinazolines
BG096072A BG60337B2 (en)	1977-11-05	1992-03-16	4-amino-2-(4-)1,4-benzodioxan-2-carbonyl(piperazine-1-il or homopiperazine-1-il)quinazolines with antihypertension effect

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB4612877		1977-11-05
GB4612877		1977-11-05

Publications (3)

Publication Number	Publication Date
DK428678A DK428678A (en)	1979-05-06
DK154082B DK154082B (en)	1988-10-10
DK154082C true DK154082C (en)	1989-02-27

Family

ID=10439957

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK428678A DK154082C (en)	1977-11-05	1978-09-27	METHOD OF ANALOGUE FOR THE PREPARATION OF 4-AMINO-6,7-DIMETHOXY-2- (PIPERAZIN-1-YL OR HOMOPIPERAZIN-1-YL) -QUINAZOLINE COMPOUNDS OR PHARMACEUTICAL ACCEPTABLE ACID ADDITIONAL SALTS

Country Status (36)

Country	Link
JP (1)	JPS5498792A (en)
AR (2)	AR219562A1 (en)
AT (1)	AT365186B (en)
AU (1)	AU509329B2 (en)
BE (1)	BE871771A (en)
CA (1)	CA1088059A (en)
CH (1)	CH643255A5 (en)
CS (2)	CS207671B2 (en)
DD (1)	DD139850A5 (en)
DE (1)	DE2847623C2 (en)
DK (1)	DK154082C (en)
EG (1)	EG13594A (en)
ES (2)	ES474805A1 (en)
FI (1)	FI64366C (en)
FR (1)	FR2407929A1 (en)
GR (1)	GR81514B (en)
HK (1)	HK94284A (en)
HU (1)	HU176306B (en)
IE (1)	IE47888B1 (en)
IL (1)	IL55857A (en)
IN (1)	IN148828B (en)
IT (1)	IT1100919B (en)
KE (1)	KE3350A (en)
LU (2)	LU80470A1 (en)
MY (1)	MY8500286A (en)
NL (2)	NL174549C (en)
NO (1)	NO150158C (en)
NZ (1)	NZ188813A (en)
PH (1)	PH13966A (en)
PL (2)	PL119419B1 (en)
PT (1)	PT68735A (en)
SE (1)	SE437518B (en)
SU (1)	SU816403A3 (en)
UA (1)	UA8324A1 (en)
YU (2)	YU40204B (en)
ZA (1)	ZA786184B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1986002644A1 (en) *	1984-11-01	1986-05-09	Takeda Chemical Industries, Ltd.	1,5-benzoxathiepin derivatives and process for their preparation
WO1985002617A1 (en) *	1983-12-14	1985-06-20	Takeda Chemical Industries. Ltd.	1,5-benzoxathiepin derivatives and process for their preparation
WO1985004658A1 (en) *	1984-04-04	1985-10-24	Takeda Chemical Industries, Ltd.	1,5-benzoxathiepine derivatives and their preparation
EP0849264A1 (en) *	1996-12-20	1998-06-24	HEUMANN PHARMA GmbH	Novel polymorphic form of doxazosin mesylate (form I)
EP0849265A1 (en) *	1996-12-20	1998-06-24	HEUMANN PHARMA GmbH	Novel polymorphic form of doxazosin mesylate (form II)
EP0849266B8 (en) *	1996-12-20	2007-10-03	Heumann PCS GmbH	Novel polymorphic form of doxazosin mesylate (form III)
TW448155B (en) *	1999-03-29	2001-08-01	Dev Center Biotechnology	Method for producing amide compounds and quinazolin derivatives
EP1403263B1 (en) *	2002-09-27	2005-06-22	Council of Scientific and Industrial Research	Process for the preparation of N-(2,3-dihydrobenzo 1,4 dioxin-2-carbonyl) piperazine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3635979A (en) *	1969-09-29	1972-01-18	Pfizer	Certain 6- and/or 7-alkoxy-substituted-2 4-bis(disubstituted amino) quinazolines
US3669968A (en) *	1970-05-21	1972-06-13	Pfizer	Trialkoxy quinazolines

1978
- 1978-09-27 DK DK428678A patent/DK154082C/en active
- 1978-10-03 IN IN712/DEL/78A patent/IN148828B/en unknown
- 1978-10-24 PH PH21726A patent/PH13966A/en unknown
- 1978-10-24 CA CA314,027A patent/CA1088059A/en not_active Expired
- 1978-10-31 UA UA2679598A patent/UA8324A1/en unknown
- 1978-10-31 SU SU782679598A patent/SU816403A3/en active
- 1978-11-02 JP JP13569578A patent/JPS5498792A/en active Granted
- 1978-11-02 PT PT68735A patent/PT68735A/en unknown
- 1978-11-02 NL NLAANVRAGE7810909,A patent/NL174549C/en not_active IP Right Cessation
- 1978-11-02 NZ NZ188813A patent/NZ188813A/en unknown
- 1978-11-02 IL IL55857A patent/IL55857A/en unknown
- 1978-11-02 AR AR274321A patent/AR219562A1/en active
- 1978-11-02 AT AT0784378A patent/AT365186B/en not_active IP Right Cessation
- 1978-11-02 YU YU2553/78A patent/YU40204B/en unknown
- 1978-11-02 DE DE2847623A patent/DE2847623C2/en not_active Expired
- 1978-11-02 GR GR57562A patent/GR81514B/el unknown
- 1978-11-02 SE SE7811382A patent/SE437518B/en not_active IP Right Cessation
- 1978-11-02 FI FI783347A patent/FI64366C/en not_active IP Right Cessation
- 1978-11-02 HU HU78PI648A patent/HU176306B/en unknown
- 1978-11-02 ZA ZA00786184A patent/ZA786184B/en unknown
- 1978-11-02 CH CH1132178A patent/CH643255A5/en not_active IP Right Cessation
- 1978-11-02 CS CS787166A patent/CS207671B2/en unknown
- 1978-11-03 BE BE191544A patent/BE871771A/en not_active IP Right Cessation
- 1978-11-03 LU LU80470A patent/LU80470A1/en unknown
- 1978-11-03 DD DD78208868A patent/DD139850A5/en unknown
- 1978-11-03 IE IE2179/78A patent/IE47888B1/en active Protection Beyond IP Right Term
- 1978-11-03 NO NO783705A patent/NO150158C/en unknown
- 1978-11-03 ES ES474805A patent/ES474805A1/en not_active Expired
- 1978-11-03 PL PL1978216980A patent/PL119419B1/en unknown
- 1978-11-03 FR FR7831126A patent/FR2407929A1/en active Granted
- 1978-11-03 IT IT29434/78A patent/IT1100919B/en active Protection Beyond IP Right Term
- 1978-11-03 AU AU41322/78A patent/AU509329B2/en not_active Expired
- 1978-11-03 PL PL1978210681A patent/PL119586B1/en unknown
- 1978-11-04 EG EG641/78A patent/EG13594A/en active
1979
- 1979-04-30 ES ES480121A patent/ES480121A0/en active Granted
- 1979-10-18 AR AR278545A patent/AR223015A1/en active
1983
- 1983-02-17 YU YU386/83A patent/YU40419B/en unknown
- 1983-11-21 KE KE3350A patent/KE3350A/en unknown
1984
- 1984-11-29 HK HK942/84A patent/HK94284A/en not_active IP Right Cessation
1985
- 1985-12-30 MY MY286/85A patent/MY8500286A/en unknown
1991
- 1991-11-22 CS CS913544A patent/CS354491A3/en unknown
1993
- 1993-06-11 NL NL930062C patent/NL930062I2/en unknown
- 1993-06-24 LU LU88331C patent/LU88331I2/en unknown

Also Published As

Publication number	Publication date
NL930062I1 (en)	1993-09-01
HU176306B (en)	1981-01-28
PL119586B1 (en)	1982-01-30
NO783705L (en)	1979-05-08
IT1100919B (en)	1985-09-28
NL174549B (en)	1984-02-01
JPS5498792A (en)	1979-08-03
DE2847623C2 (en)	1983-06-01
CA1088059A (en)	1980-10-21
AU509329B2 (en)	1980-05-08
IL55857A (en)	1982-07-30
NO150158B (en)	1984-05-21
ES474805A1 (en)	1980-01-16
ES8308559A1 (en)	1980-07-16
PT68735A (en)	1978-12-01
YU255378A (en)	1983-06-30
FI64366C (en)	1983-11-10
IL55857A0 (en)	1979-01-31
CS207671B2 (en)	1981-08-31
LU88331I2 (en)	1994-05-04
LU80470A1 (en)	1980-06-05
IE782179L (en)	1979-05-05
FR2407929A1 (en)	1979-06-01
IE47888B1 (en)	1984-07-11
PH13966A (en)	1980-11-12
SE437518B (en)	1985-03-04
SU816403A3 (en)	1981-03-23
NL7810909A (en)	1979-05-08
PL119419B1 (en)	1981-12-31
DK428678A (en)	1979-05-06
DE2847623A1 (en)	1979-05-23
MY8500286A (en)	1985-12-31
AR223015A1 (en)	1981-07-15
EG13594A (en)	1982-03-31
NL174549C (en)	1984-07-02
HK94284A (en)	1984-12-07
FI64366B (en)	1983-07-29
DK154082B (en)	1988-10-10
IT7829434A0 (en)	1978-11-03
CH643255A5 (en)	1984-05-30
PL210681A1 (en)	1979-11-05
AR219562A1 (en)	1980-08-29
CS354491A3 (en)	1992-06-17
NL930062I2 (en)	1993-11-16
YU38683A (en)	1983-06-30
YU40419B (en)	1985-12-31
YU40204B (en)	1985-08-31
UA8324A1 (en)	1996-03-29
ATA784378A (en)	1981-05-15
FI783347A (en)	1979-05-06
JPS5625233B2 (en)	1981-06-11
NZ188813A (en)	1980-10-08
AT365186B (en)	1981-12-28
NO150158C (en)	1984-08-29
FR2407929B1 (en)	1981-02-27
SE7811382L (en)	1979-05-06
BE871771A (en)	1979-05-03
AU4132278A (en)	1979-05-17
KE3350A (en)	1983-12-16
GR81514B (en)	1984-12-11
DD139850A5 (en)	1980-01-23
ES480121A0 (en)	1980-07-16
IN148828B (en)	1981-06-27
ZA786184B (en)	1979-10-31

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