DK139098B - Analogifremgangsmåde til fremstilling af imidazoliner eller ikke-toxiske, farmaceutisk anvendelige syreadditionssalte deraf. - Google Patents

Analogifremgangsmåde til fremstilling af imidazoliner eller ikke-toxiske, farmaceutisk anvendelige syreadditionssalte deraf.

Info

Publication number
DK139098B
DK139098B DK403972AA DK403972A DK139098B DK 139098 B DK139098 B DK 139098B DK 403972A A DK403972A A DK 403972AA DK 403972 A DK403972 A DK 403972A DK 139098 B DK139098 B DK 139098B
Authority
DK
Denmark
Prior art keywords
imidazolines
preparation
acid addition
addition salts
toxic pharmaceutically
Prior art date
Application number
DK403972AA
Other languages
Danish (da)
English (en)
Other versions
DK139098C (xx
Inventor
William Lesley Matier
William Timmey Comer
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DK139098B publication Critical patent/DK139098B/da
Application granted granted Critical
Publication of DK139098C publication Critical patent/DK139098C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/42Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44Nitrogen atoms not forming part of a nitro radical
    • C07D233/46Nitrogen atoms not forming part of a nitro radical with only hydrogen atoms attached to said nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44Nitrogen atoms not forming part of a nitro radical
    • C07D233/48Nitrogen atoms not forming part of a nitro radical with acyclic hydrocarbon or substituted acyclic hydrocarbon radicals, attached to said nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44Nitrogen atoms not forming part of a nitro radical
    • C07D233/52Nitrogen atoms not forming part of a nitro radical with hetero atoms directly attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK403972AA 1971-08-16 1972-08-15 Analogifremgangsmåde til fremstilling af imidazoliner eller ikke-toxiske, farmaceutisk anvendelige syreadditionssalte deraf. DK139098B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17232171A 1971-08-16 1971-08-16
US00268380A US3821244A (en) 1971-08-16 1972-07-03 2-amino-4-phenyl-2-imidazolines

Publications (2)

Publication Number Publication Date
DK139098B true DK139098B (da) 1978-12-18
DK139098C DK139098C (xx) 1979-05-28

Family

ID=26867960

Family Applications (1)

Application Number Title Priority Date Filing Date
DK403972AA DK139098B (da) 1971-08-16 1972-08-15 Analogifremgangsmåde til fremstilling af imidazoliner eller ikke-toxiske, farmaceutisk anvendelige syreadditionssalte deraf.

Country Status (16)

Country Link
US (1) US3821244A (xx)
JP (1) JPS5719106B2 (xx)
BE (1) BE787617A (xx)
CA (1) CA1018174A (xx)
CH (2) CH591451A5 (xx)
DE (1) DE2240256A1 (xx)
DK (1) DK139098B (xx)
FR (1) FR2150766B1 (xx)
GB (1) GB1347930A (xx)
HU (1) HU165660B (xx)
IE (1) IE36865B1 (xx)
IL (1) IL40123A (xx)
NL (1) NL7211173A (xx)
PH (2) PH11940A (xx)
SE (1) SE406763B (xx)
YU (1) YU35355B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3914249A (en) * 1973-10-30 1975-10-21 Mead Johnson & Co 4-(3,4-Dichlorophenyl)-2-(methylamino)-2-imadazoline
US3953348A (en) * 1973-12-13 1976-04-27 Standard Oil Company Oil-soluble reaction products of intermediate (a) from a high molecular weight olefin polymer, acetonitrile, and chlorine with (b) a piperazine, and lubricant compositions containing the same
HU179019B (en) * 1978-11-01 1982-08-28 Gyogyszekutato Intezet Process for preparing 4-//3,4-dialkoxy-phenyl/-alkyl/- 2imidazolidinone derivatives
JPS5877051U (ja) * 1981-11-16 1983-05-24 富士通株式会社 Icアダプタ
EP0200947B1 (de) * 1985-04-26 1990-09-12 F. Hoffmann-La Roche Ag 1,3-Disubstituierte Imidazoliumsalze
HUP9802260A3 (en) * 1995-09-07 1999-10-28 Novartis Ag Substituted phosphinic compounds preparation and their use as pharmaceuticals and pharmaceutical compositions
HUP0400405A3 (en) * 2004-02-10 2009-03-30 Sanofi Synthelabo Pyrimidine derivatives, process for producing them, their use, pharmaceutical compositions containing them and their intermediates

Also Published As

Publication number Publication date
SE406763B (sv) 1979-02-26
YU35355B (en) 1980-12-31
FR2150766A1 (xx) 1973-04-13
HU165660B (xx) 1974-10-28
NL7211173A (xx) 1973-02-20
DE2240256A1 (de) 1973-02-22
JPS4829770A (xx) 1973-04-19
FR2150766B1 (xx) 1976-05-21
GB1347930A (en) 1974-02-27
JPS5719106B2 (xx) 1982-04-20
IE36865B1 (en) 1977-03-16
PH11915A (en) 1978-09-08
YU207472A (en) 1980-06-30
US3821244A (en) 1974-06-28
DK139098C (xx) 1979-05-28
PH11940A (en) 1978-09-15
CH579055A5 (xx) 1976-08-31
CH591451A5 (xx) 1977-09-15
IE36865L (en) 1973-02-16
BE787617A (fr) 1973-02-16
IL40123A (en) 1975-05-22
IL40123A0 (en) 1972-10-29
CA1018174A (en) 1977-09-27

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