DE69434926D1 - Menschlicher gewebsinhibitor von metalloproteinase-4 - Google Patents

Menschlicher gewebsinhibitor von metalloproteinase-4

Info

Publication number
DE69434926D1
DE69434926D1 DE69434926T DE69434926T DE69434926D1 DE 69434926 D1 DE69434926 D1 DE 69434926D1 DE 69434926 T DE69434926 T DE 69434926T DE 69434926 T DE69434926 T DE 69434926T DE 69434926 D1 DE69434926 D1 DE 69434926D1
Authority
DE
Germany
Prior art keywords
polypeptide
disclosed
tissue inhibitor
human tissue
metaloproteinase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69434926T
Other languages
English (en)
Other versions
DE69434926T2 (de
Inventor
John M Greene
Craig A Rosen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22243411&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69434926(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Application granted granted Critical
Publication of DE69434926D1 publication Critical patent/DE69434926D1/de
Publication of DE69434926T2 publication Critical patent/DE69434926T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69434926T 1994-12-13 1994-12-13 Menschlicher gewebsinhibitor von metalloproteinase-4 Expired - Fee Related DE69434926T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1994/014498 WO1996018725A1 (en) 1994-12-13 1994-12-13 Human tissue inhibitor of metalloproteinase-4

Publications (2)

Publication Number Publication Date
DE69434926D1 true DE69434926D1 (de) 2007-04-05
DE69434926T2 DE69434926T2 (de) 2008-03-06

Family

ID=22243411

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69434926T Expired - Fee Related DE69434926T2 (de) 1994-12-13 1994-12-13 Menschlicher gewebsinhibitor von metalloproteinase-4

Country Status (9)

Country Link
US (4) US6300310B1 (de)
EP (1) EP0815202B1 (de)
JP (1) JPH10510986A (de)
AT (1) ATE354638T1 (de)
AU (1) AU708829B2 (de)
DE (1) DE69434926T2 (de)
ES (1) ES2281898T3 (de)
NZ (1) NZ279963A (de)
WO (1) WO1996018725A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544761B2 (en) 1994-12-13 2003-04-08 Human Genome Sciences, Inc. Human tissue inhibitor of metalloproteinase-4
AU708829B2 (en) 1994-12-13 1999-08-12 Human Genome Sciences, Inc. Human tissue inhibitor of metalloproteinase-4
US5643752A (en) * 1996-01-18 1997-07-01 Incyte Pharmaceuticals, Inc. Tissue inhibitor of metalloproteinases
US7129061B1 (en) * 1996-08-07 2006-10-31 Biogen Idec Ma Inc. Tumor necrosis factor related ligand
WO2000032175A2 (en) * 1998-12-02 2000-06-08 Pfizer Products Inc. METHODS AND COMPOSITIONS FOR RESTORING CONFORMATIONAL STABILITY OF A PROTEIN OF THE p53 FAMILY
MXPA01007163A (es) 1999-01-15 2002-03-27 Biogen Inc Antagonistas de tweak y de receptores de tweak y su uso para tratar trastornos inmunologicos.
AU3735900A (en) * 1999-03-11 2000-09-28 Human Genome Sciences, Inc. Methods of treatment and prevention of restenosis
EP1923068B1 (de) * 1999-09-24 2011-06-08 Proteon Therapeutics, Inc. Systeme und Verfahren zum Öffnen von obstruierten biologischen Kanälen
US7063838B1 (en) 1999-09-24 2006-06-20 Proteon Therapeutics Llc Methods for treating an artery or vein in a human subject
US7632494B2 (en) 1999-09-24 2009-12-15 Proteon Therapeutics, Inc. Methods for enlarging the diameter of a biological conduit in a human subject
US7115665B1 (en) 2000-11-16 2006-10-03 Onocozyme Pharma, Inc. Inhibitors of endo-exonuclease activity for treating cancer
EP1363657A2 (de) 2000-05-08 2003-11-26 Biogen, Inc. Methode zur förderung der gefässneubildung durch ein tweak agonist und einen angiogenischen faktor
US20020198207A1 (en) * 2000-05-18 2002-12-26 Kath John Charles Novel Hexanoic acid derivatives
US7208151B2 (en) 2001-09-12 2007-04-24 Biogen Idec Ma Inc. Tweak receptor agonists as anti-angiogenic agents
US7071164B2 (en) 2001-08-16 2006-07-04 Kimberly-Clark Worldwide, Inc. Anti-cancer and wound healing compounds
US6906036B2 (en) 2001-08-16 2005-06-14 Kimberly-Clark Worldwide, Inc. Anti-aging and wound healing compounds
US7094754B2 (en) 2001-08-16 2006-08-22 Kimberly-Clark Worldwide, Inc. Anti-aging and wound healing compounds
US7186693B2 (en) 2001-08-16 2007-03-06 Kimberly - Clark Worldwide, Inc. Metalloproteinase inhibitors for wound healing
CA2480745A1 (en) 2002-04-09 2003-10-23 Biogen, Inc. Methods for treating tweak-related conditions
US7148194B2 (en) 2002-12-30 2006-12-12 Kimberly-Clark Worldwide, Inc. Method to increase fibronectin
US7189700B2 (en) 2003-06-20 2007-03-13 Kimberly-Clark Worldwide, Inc. Anti-chrondrosarcoma compounds
AU2006214179A1 (en) 2005-02-17 2006-08-24 Biogen Idec Ma Inc. Treating neurological disorders
WO2006122187A2 (en) 2005-05-10 2006-11-16 Biogen Idec Ma Inc. Treating and evaluating inflammatory disorders
WO2006138219A2 (en) 2005-06-13 2006-12-28 Biogen Idec Ma Inc. Methods of diagnosis / prognosis of inflammatory conditions
KR101143891B1 (ko) 2009-12-29 2012-05-11 한국기초과학지원연구원 단백질의 비정상적인 당쇄화를 이용하는 암진단 마커
WO2019134526A1 (zh) * 2018-01-03 2019-07-11 西交利物浦大学 膜型金属蛋白酶抑制蛋白和包含其的药物和药物组合物及各自的用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0464147B1 (de) * 1989-03-21 2002-06-26 THE UNITED STATES OF AMERICA as represented by the Secretary UNITED STATES DEPARTMENT OF COMMERCE Matrizenmetalloproteinase-inhibitor-peptide
WO1990014363A1 (en) * 1989-05-19 1990-11-29 Amgen Inc. Metalloproteinase inhibitor
AU708829B2 (en) 1994-12-13 1999-08-12 Human Genome Sciences, Inc. Human tissue inhibitor of metalloproteinase-4
US5643752A (en) * 1996-01-18 1997-07-01 Incyte Pharmaceuticals, Inc. Tissue inhibitor of metalloproteinases

Also Published As

Publication number Publication date
AU708829B2 (en) 1999-08-12
EP0815202A1 (de) 1998-01-07
US6828424B2 (en) 2004-12-07
JPH10510986A (ja) 1998-10-27
US6448042B1 (en) 2002-09-10
DE69434926T2 (de) 2008-03-06
US6391853B1 (en) 2002-05-21
EP0815202A4 (de) 2002-10-16
US6300310B1 (en) 2001-10-09
US20020115187A1 (en) 2002-08-22
ATE354638T1 (de) 2007-03-15
EP0815202B1 (de) 2007-02-21
ES2281898T3 (es) 2007-10-01
WO1996018725A1 (en) 1996-06-20
AU1724795A (en) 1996-07-03
NZ279963A (en) 1998-10-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee