DE3482590D1 - Carboxyalkyl-peptid-derivate. - Google Patents

Carboxyalkyl-peptid-derivate.

Info

Publication number
DE3482590D1
DE3482590D1 DE8484112744T DE3482590T DE3482590D1 DE 3482590 D1 DE3482590 D1 DE 3482590D1 DE 8484112744 T DE8484112744 T DE 8484112744T DE 3482590 T DE3482590 T DE 3482590T DE 3482590 D1 DE3482590 D1 DE 3482590D1
Authority
DE
Germany
Prior art keywords
carboxyalkyl
peptide derivatives
peptide
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8484112744T
Other languages
English (en)
Inventor
Keith Mccullagh
Harry Wadsworth
Michael Hann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/599,307 external-priority patent/US4511504A/en
Priority claimed from US06/662,129 external-priority patent/US4568666A/en
Application filed by GD Searle LLC filed Critical GD Searle LLC
Application granted granted Critical
Publication of DE3482590D1 publication Critical patent/DE3482590D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043—Leu-amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE8484112744T 1984-04-12 1984-10-23 Carboxyalkyl-peptid-derivate. Expired - Fee Related DE3482590D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/599,307 US4511504A (en) 1983-04-26 1984-04-12 Carboxyalkyl peptide derivatives
US06/662,129 US4568666A (en) 1984-10-18 1984-10-18 Carboxylalkyl peptide derivatives

Publications (1)

Publication Number Publication Date
DE3482590D1 true DE3482590D1 (de) 1990-08-02

Family

ID=27083314

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484112744T Expired - Fee Related DE3482590D1 (de) 1984-04-12 1984-10-23 Carboxyalkyl-peptid-derivate.

Country Status (2)

Country Link
EP (1) EP0159396B1 (de)
DE (1) DE3482590D1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5183900A (en) * 1990-11-21 1993-02-02 Galardy Richard E Matrix metalloprotease inhibitors
US5239078A (en) * 1990-11-21 1993-08-24 Glycomed Incorporated Matrix metalloprotease inhibitors
US5268384A (en) * 1990-11-21 1993-12-07 Galardy Richard E Inhibition of angiogenesis by synthetic matrix metalloprotease inhibitors
US5114953A (en) * 1990-11-21 1992-05-19 University Of Florida Treatment for tissue ulceration
US5189178A (en) * 1990-11-21 1993-02-23 Galardy Richard E Matrix metalloprotease inhibitors
AU4329399A (en) 1998-07-30 2000-02-21 Warner-Lambert Company Tyrosine-derived compounds as calcium channel antagonists
US6180677B1 (en) 1999-06-02 2001-01-30 Warner-Lambert Company Tyrosine-derived compounds as calcium channel antagonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58849A (en) 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
GB8311286D0 (en) * 1983-04-26 1983-06-02 Searle & Co Carboxyalkyl peptide derivatives

Also Published As

Publication number Publication date
EP0159396A2 (de) 1985-10-30
EP0159396A3 (en) 1987-05-06
EP0159396B1 (de) 1990-06-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee