DD130352A5 - Verfahren zur herstellung von prostaglandin-derivaten - Google Patents

Verfahren zur herstellung von prostaglandin-derivaten

Info

Publication number
DD130352A5
DD130352A5 DD7700198124A DD19812477A DD130352A5 DD 130352 A5 DD130352 A5 DD 130352A5 DD 7700198124 A DD7700198124 A DD 7700198124A DD 19812477 A DD19812477 A DD 19812477A DD 130352 A5 DD130352 A5 DD 130352A5
Authority
DD
German Democratic Republic
Prior art keywords
production
prostaglandine derivatives
prostaglandine
derivatives
Prior art date
Application number
DD7700198124A
Other languages
German (de)
English (en)
Inventor
Souli Nanthavong
Charles Pigerol
Pierre Eymard
Jacques Simiand
Original Assignee
Labaz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz filed Critical Labaz
Publication of DD130352A5 publication Critical patent/DD130352A5/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/126Acids containing more than four carbon atoms
    • C07C53/128Acids containing more than four carbon atoms the carboxylic group being bound to a carbon atom bound to at least two other carbon atoms, e.g. neo-acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
DD7700198124A 1976-03-31 1977-03-29 Verfahren zur herstellung von prostaglandin-derivaten DD130352A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL49325A IL49325A (en) 1976-03-31 1976-03-31 8-aza-11-deoxy-pge1 derivatives,their preparation and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
DD130352A5 true DD130352A5 (de) 1978-03-22

Family

ID=11048789

Family Applications (1)

Application Number Title Priority Date Filing Date
DD7700198124A DD130352A5 (de) 1976-03-31 1977-03-29 Verfahren zur herstellung von prostaglandin-derivaten

Country Status (18)

Country Link
US (1) US4115401A (fr)
JP (1) JPS52142060A (fr)
BE (1) BE852941A (fr)
CA (1) CA1074804A (fr)
CH (2) CH624101A5 (fr)
DD (1) DD130352A5 (fr)
DE (1) DE2714129A1 (fr)
ES (1) ES457385A1 (fr)
FR (1) FR2346332A1 (fr)
GB (1) GB1574246A (fr)
HU (1) HU178040B (fr)
IL (1) IL49325A (fr)
IT (1) IT1075373B (fr)
NL (1) NL7703503A (fr)
NO (1) NO149428C (fr)
PL (3) PL108289B1 (fr)
SE (1) SE417603B (fr)
SU (3) SU676162A3 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES482357A1 (es) * 1978-07-11 1980-08-16 Glaxo Group Ltd Procedimiento para preparar compuestos prostanoides.
US4320136A (en) * 1980-08-11 1982-03-16 E. I. Du Pont De Nemours And Company 8-Aza-16,16-difluoroprostanoids
US4530933A (en) * 1982-12-27 1985-07-23 E. I. Du Pont De Nemours And Company 8-Aza-13-thiaprostanoids and a method of use thereof as anti-ulcer agents
US4456613A (en) * 1982-12-27 1984-06-26 E. I. Du Pont De Nemours And Company 6-Keto- and 6-hydroxy-8-azaprostanoids and anti-ulcer use thereof
CZ20022048A3 (cs) 1999-12-22 2004-03-17 Pfizer Products Inc. Selektivní agonisty receptoru EP4 při léčení osteoporosy
CZ20031257A3 (cs) * 2000-11-27 2004-04-14 Pfizer Products Inc. Selektivní agonisty receptoru EP4 při léčení osteoporosy
DE60208568T2 (de) 2001-07-16 2006-10-05 F. Hoffmann-La Roche Ag Prostaglandinanaloga als ep4-rezeptoragonisten
JP4211605B2 (ja) * 2001-07-16 2009-01-21 小野薬品工業株式会社 プロスタノイドアゴニストとしての2ピロリドン誘導体
PL367740A1 (en) 2001-07-23 2005-03-07 Ono Pharmaceutical Co, Ltd. Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient
US7402605B2 (en) 2002-03-05 2008-07-22 Ono Pharmaceutical Co., Ltd. 8-azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient
EP1490055A1 (fr) * 2002-03-18 2004-12-29 Pfizer Products Inc. Utilisation d'agonistes du recepteur ep4 selectif pour le traitement de l'insuffisance hepatique, de la perte de la permeabilite du canal arteriel, du glaucome ou de l'hypertension oculaire
PL378342A1 (pl) * 2003-01-10 2006-03-20 F. Hoffmann-La Roche Ag Pochodne 2-piperydonu jako agoniści prostaglandyn
US7179820B2 (en) 2003-06-06 2007-02-20 Allergan, Inc. Piperidinyl prostaglandin E analogs
US20080058375A1 (en) * 2004-01-08 2008-03-06 Elworthy Todd R 2-Piperidone derivatives as prostaglandin antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975399A (en) * 1974-08-06 1976-08-17 E. I. Du Pont De Nemours And Company 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones

Also Published As

Publication number Publication date
NL7703503A (nl) 1977-10-04
DE2714129A1 (de) 1977-10-13
CH624101A5 (fr) 1981-07-15
HU178040B (en) 1982-02-28
JPS52142060A (en) 1977-11-26
CA1074804A (fr) 1980-04-01
GB1574246A (en) 1980-09-03
SU676162A3 (ru) 1979-07-25
US4115401A (en) 1978-09-19
SE7703698L (sv) 1977-10-01
NO149428B (no) 1984-01-09
PL197005A1 (pl) 1978-10-09
FR2346332B1 (fr) 1980-05-09
BE852941A (fr) 1977-09-28
NO771134L (no) 1977-10-03
IT1075373B (it) 1985-04-22
SE417603B (sv) 1981-03-30
PL108289B1 (pl) 1980-03-31
NO149428C (no) 1984-04-18
FR2346332A1 (fr) 1977-10-28
PL107544B1 (pl) 1980-02-29
CH628032A5 (fr) 1982-02-15
SU715019A3 (ru) 1980-02-05
IL49325A (en) 1979-11-30
SU837321A3 (ru) 1981-06-07
IL49325A0 (en) 1976-05-31
PL107643B1 (pl) 1980-02-29
ES457385A1 (es) 1978-02-01

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