CU20190030A7 - Composiciones de vacunas antineumocócicas polivalentes que comprenden conjugados de polisacárido-proteína - Google Patents
Composiciones de vacunas antineumocócicas polivalentes que comprenden conjugados de polisacárido-proteínaInfo
- Publication number
- CU20190030A7 CU20190030A7 CU2019000030A CU20190030A CU20190030A7 CU 20190030 A7 CU20190030 A7 CU 20190030A7 CU 2019000030 A CU2019000030 A CU 2019000030A CU 20190030 A CU20190030 A CU 20190030A CU 20190030 A7 CU20190030 A7 CU 20190030A7
- Authority
- CU
- Cuba
- Prior art keywords
- polyvalent
- pneumococcal
- antineumococcal
- compositions
- vaccine compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 229960005486 vaccine Drugs 0.000 title 1
- 102000014914 Carrier Proteins Human genes 0.000 abstract 2
- 108010078791 Carrier Proteins Proteins 0.000 abstract 2
- 150000004676 glycans Chemical class 0.000 abstract 2
- 229940124733 pneumococcal vaccine Drugs 0.000 abstract 2
- 229920001282 polysaccharide Polymers 0.000 abstract 2
- 239000005017 polysaccharide Substances 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 229940124959 polyvalent pneumococcal vaccine Drugs 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
<p>La presente divulgación se refiere a composiciones de vacunas antineumocócicas polivalentes que comprenden serotipos de polisacáridos neumocócicos capsulares, cada uno conjugado individualmente con proteínas portadoras. AI conjugarse, Ia combinación del serotipo de polisacárido capsular neumocócico y Ia proteína portadora se denomina en Ia presente un conjugado de polisacárido-proteína. Las composiciones de vacunas antineumocócicas pueden comprender además uno o más de los siguientes: un portador aceptable desde el punto de vista farmacéutico, un diluyente aceptable desde el punto de vista farmacéutico, un amortiguador, un conservante, un estabilizante, un adyuvante y/o un excipiente de liofilización. También se proporcionan métodos para preparar y administrar las composiciones de vacunas antineumocócicas descritas en Ia presente.</p>
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN201641033563 | 2016-09-30 | ||
PCT/US2017/054237 WO2018064444A1 (en) | 2016-09-30 | 2017-09-29 | Multivalent pneumococcal vaccine compositions comprising polysaccharide-protein conjugates |
Publications (2)
Publication Number | Publication Date |
---|---|
CU20190030A7 true CU20190030A7 (es) | 2019-11-04 |
CU24660B1 CU24660B1 (es) | 2023-05-11 |
Family
ID=60117775
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CU2019000030A CU24660B1 (es) | 2016-09-30 | 2017-09-29 | Composiciones de vacunas multivalentes que comprenden conjugados de polisacárido-proteína de streptococcus pneumoniae utilizando proteínas portadoras psaa y crm197 |
Country Status (20)
Country | Link |
---|---|
US (1) | US11547752B2 (es) |
EP (1) | EP3518965A1 (es) |
JP (2) | JP2019529497A (es) |
KR (1) | KR102608081B1 (es) |
CN (1) | CN109789198B (es) |
AU (1) | AU2017336806B2 (es) |
BR (1) | BR112019006278A2 (es) |
CA (1) | CA3037056A1 (es) |
CL (1) | CL2019000849A1 (es) |
CO (1) | CO2019002955A2 (es) |
CU (1) | CU24660B1 (es) |
EA (1) | EA201990838A1 (es) |
IL (2) | IL265623B2 (es) |
MX (1) | MX2019003593A (es) |
NZ (1) | NZ752348A (es) |
PH (1) | PH12019500672A1 (es) |
SA (1) | SA519401317B1 (es) |
UA (1) | UA126385C2 (es) |
WO (1) | WO2018064444A1 (es) |
ZA (1) | ZA201901170B (es) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY182282A (en) | 2015-05-04 | 2021-01-18 | Pfizer | Group b streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereof |
WO2017173415A2 (en) | 2016-03-31 | 2017-10-05 | Liffey Biotech Limited | Saccharide-polypeptide conjugate compositions and methods of use thereof |
KR20190103256A (ko) | 2016-12-30 | 2019-09-04 | 수트로박스, 인코포레이티드 | 비자연 아미노산을 갖는 폴리펩타이드-항원 접합체 |
US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
US10729763B2 (en) | 2017-06-10 | 2020-08-04 | Inventprise, Llc | Mixtures of polysaccharide-protein pegylated compounds |
GB201711635D0 (en) * | 2017-07-19 | 2017-08-30 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
TWI725359B (zh) | 2017-12-06 | 2021-04-21 | 美商默沙東藥廠 | 包含肺炎鏈球菌多醣-蛋白結合物之組合物及其使用方法 |
CA3087572A1 (en) * | 2018-02-05 | 2019-08-08 | Sanofi Pasteur Inc. | Multivalent pneumococcal polysaccharide-protein conjugate composition |
IL304977A (en) | 2018-02-05 | 2023-10-01 | Sanofi Pasteur Inc | A multivalent pneumococcal protein-polysaccharide conjugate preparation |
US11951162B2 (en) | 2018-04-18 | 2024-04-09 | Sk Bioscience Co., Ltd. | Streptococcus pneumoniae capsular polysaccharides and immunogenic conjugate thereof |
WO2020010000A1 (en) * | 2018-07-04 | 2020-01-09 | Sutrovax, Inc. | Improved methods for the preparation of immunogenic conjugates |
MX2020014118A (es) * | 2018-07-04 | 2021-06-18 | Vaxcyte Inc | Mejoras en conjugados inmunogenicos. |
EA202190318A1 (ru) * | 2018-07-21 | 2021-04-29 | Байолоджикал И Лимитед | Составы вакцин, содержащие систему консервантов |
CN113164581A (zh) * | 2018-09-23 | 2021-07-23 | 生物E有限公司 | 纯化的肺炎链球菌荚膜多糖 |
AU2019358622A1 (en) * | 2018-10-12 | 2021-06-17 | Biological E Limited | Multivalent pneumococcal polysaccharide-protein conjugate vaccine |
BR112021011961A8 (pt) * | 2018-12-19 | 2023-02-07 | Merck Sharp & Dohme | Composições compreendendo conjugados de polissacarídeo-proteína de streptococcus pneumoniae e métodos de uso dos mesmos |
WO2020152706A1 (en) * | 2019-01-21 | 2020-07-30 | Biological E Limited | Multivalent pneumococcal conjugate vaccine compositions |
WO2020157772A1 (en) * | 2019-01-28 | 2020-08-06 | Biological E Limited | Multivalent pneumococcal polysaccharide-protein conjugate vaccine compositions |
CN109771640A (zh) * | 2019-02-28 | 2019-05-21 | 北京智飞绿竹生物制药有限公司 | 多价肺炎球菌结合疫苗 |
CN114025784A (zh) * | 2019-06-05 | 2022-02-08 | 默沙东公司 | 用针对肺炎链球菌血清型29进行保护的免疫原性组合物治疗患者的方法 |
AU2020286360A1 (en) * | 2019-06-05 | 2021-12-23 | Merck Sharp & Dohme Llc | An immunogenic serotype 35B pneumococcal polysaccharide-protein conjugate and conjugation process for making the same |
CN110302375A (zh) * | 2019-06-27 | 2019-10-08 | 康希诺生物股份公司 | 一种糖缀合物及其用途 |
CN114364397B (zh) * | 2019-07-18 | 2024-03-29 | 赛特瑞恩股份有限公司 | 含多价肺炎链球菌多糖-蛋白偶联物的免疫原性组合物、药物组合物及其用途 |
CN114728050A (zh) * | 2019-07-31 | 2022-07-08 | 圣诺菲·帕斯图尔公司 | 多价肺炎球菌多糖-蛋白质缀合物组合物及其使用方法 |
CN110804097B (zh) * | 2019-10-30 | 2021-02-26 | 云南沃森生物技术股份有限公司 | 一种同时制备两种单克隆抗体的方法 |
AU2021207701A1 (en) * | 2020-01-17 | 2022-09-15 | Bill & Melinda Gates Foundation | Multivalent Streptococcus vaccines |
WO2022035816A1 (en) * | 2020-08-10 | 2022-02-17 | Inventprise, Llc | Multivalent pneumococcal glycoconjugate vaccines containing emerging serotype 24f |
KR20220102871A (ko) * | 2021-01-14 | 2022-07-21 | (주)셀트리온 | 다가 폐렴구균 다당류-단백질 접합체를 포함하는 면역원성 조성물 |
WO2022180648A1 (en) * | 2021-02-26 | 2022-09-01 | Biological E Limited | Activated-quenched polysaccharide and improved methods for quantification of polysaccharide in a vaccine composition |
US20240181028A1 (en) * | 2022-11-22 | 2024-06-06 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0027888B1 (en) | 1979-09-21 | 1986-04-16 | Hitachi, Ltd. | Semiconductor switch |
US5360897A (en) | 1981-08-31 | 1994-11-01 | The University Of Rochester | Immunogenic conjugates of streptococcus pneumonial capsular polymer and toxin or in toxiad |
US4902506A (en) | 1983-07-05 | 1990-02-20 | The University Of Rochester | Immunogenic conjugates |
US4673574A (en) | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
US5854416A (en) | 1991-11-14 | 1998-12-29 | The United States Of America As Represented By The Department Of Health And Human Services | Streptococcus pneumoniae 37-KDA surface adhesin a protein and nucleic acids coding therefor |
ATE245446T1 (de) | 1992-02-11 | 2003-08-15 | Jackson H M Found Military Med | Dualer träger für immunogene konstrukte |
DK0616034T3 (da) | 1993-03-05 | 2005-02-21 | Wyeth Corp | Plasmid til fremstilling af CRM-protein og diphtheria toxin |
CA2171942C (en) | 1993-09-22 | 2010-12-14 | Andrew Lees | Method of activating soluble carbohydrate using novel cyanylating reagents for the production of immunogenic constructs |
JPH11502820A (ja) | 1995-03-22 | 1999-03-09 | ヘンリー エム.ジャクソン ファウンデイション フォー ザ アドバンスメント オブ ミリタリー メディスン | 有機シアン化試薬により活性化された可溶性炭水化物を使用する免疫原性構築物の製造 |
US6299881B1 (en) | 1997-03-24 | 2001-10-09 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts |
FR2763244B1 (fr) * | 1997-05-14 | 2003-08-01 | Pasteur Merieux Serums Vacc | Composition vaccinale multivalente a porteur mixte |
US8048432B2 (en) | 2003-08-06 | 2011-11-01 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Polysaccharide-protein conjugate vaccines |
US7709001B2 (en) | 2005-04-08 | 2010-05-04 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
US7955605B2 (en) | 2005-04-08 | 2011-06-07 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
DK1868645T3 (da) | 2005-04-08 | 2012-04-10 | Wyeth Llc | Multivalent pneumokok-sakkarid-protein-konjugat-sammensætning |
EP3470080A1 (en) | 2005-12-22 | 2019-04-17 | GlaxoSmithKline Biologicals S.A. | Vaccine comprising streptococcus pneumoniae capsular polysaccharide conjugates |
KR101411425B1 (ko) | 2006-03-17 | 2014-06-24 | 더 거버먼트 오브 더 유나이티드 스테이츠 오브 아메리카 에즈 레프리젠티드 바이 더 세크러테리 오브 더 디파트먼트 오브 헬스 앤드 휴먼 서비시즈 | 복합 다가 면역원성 콘쥬게이트의 제조 방법 |
WO2007127668A2 (en) * | 2006-04-26 | 2007-11-08 | Wyeth | Novel processes for coating container means which inhibit precipitation of polysaccharide-protein conjugate formulations |
KR20100045445A (ko) | 2007-06-26 | 2010-05-03 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 스트렙토코쿠스 뉴모니애 캡슐 다당류 컨쥬게이트를 포함하는 백신 |
US8003112B2 (en) * | 2009-04-16 | 2011-08-23 | Howard University | Meningococcal and pneumococcal conjugate vaccine and method of using same |
CN101590224A (zh) | 2009-06-30 | 2009-12-02 | 广州精达医学科技有限公司 | 高效14价肺炎球菌结合疫苗 |
TW201136603A (en) * | 2010-02-09 | 2011-11-01 | Merck Sharp & Amp Dohme Corp | 15-valent pneumococcal polysaccharide-protein conjugate vaccine composition |
GB201003924D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Immunogenic composition |
WO2011151841A1 (en) * | 2010-05-31 | 2011-12-08 | Panacea Biotec Limited | Fermentation process for streptococcus pneumoniae |
KR102057217B1 (ko) | 2012-06-20 | 2020-01-22 | 에스케이바이오사이언스 주식회사 | 다가 폐렴구균 다당류-단백질 접합체 조성물 |
CN103623401A (zh) | 2012-08-23 | 2014-03-12 | 北京科兴中维生物技术有限公司 | 多价肺炎球菌荚膜多糖-蛋白质共轭组合物及其制备方法 |
CN103656632B (zh) | 2012-09-24 | 2016-01-13 | 北京科兴中维生物技术有限公司 | 多价肺炎球菌荚膜多糖组合物、其制备方法及应用 |
CN103656631B (zh) | 2012-09-24 | 2015-08-19 | 北京科兴中维生物技术有限公司 | 多价肺炎球菌荚膜多糖-蛋白缀合物组合物及其制备方法 |
KR20140075201A (ko) | 2012-12-11 | 2014-06-19 | 에스케이케미칼주식회사 | 다가 폐렴구균 다당류-단백질 접합체 조성물 |
KR20140075196A (ko) | 2012-12-11 | 2014-06-19 | 에스케이케미칼주식회사 | 다가 폐렴구균 다당류-단백질 접합체 조성물 |
CN104069488A (zh) | 2013-03-29 | 2014-10-01 | 北京科兴中维生物技术有限公司 | 多价肺炎球菌荚膜多糖-蛋白质共轭组合物及其制备方法 |
CA2968491C (en) | 2014-11-20 | 2023-09-26 | Biological E Limited | Codon optimized polynucleotide for high level expression of crm197 |
MX2017013855A (es) | 2015-04-28 | 2018-03-15 | Biological E Ltd | Metodo para la separacion de proteina y otras impurezas de polisacaridos capsulares microbianos. |
AU2016285017B2 (en) * | 2015-06-23 | 2022-03-03 | Biological E Limited | Multivalent pneumococcal conjugate vaccine |
EP3296741B1 (en) * | 2016-09-14 | 2019-08-21 | Serum Institute of India Private Limited | Multiplex bead based assay for quantification of multiple types of carrier protein in a multivalent conjugate vaccine composition |
-
2017
- 2017-09-29 JP JP2019517383A patent/JP2019529497A/ja not_active Withdrawn
- 2017-09-29 MX MX2019003593A patent/MX2019003593A/es unknown
- 2017-09-29 BR BR112019006278A patent/BR112019006278A2/pt unknown
- 2017-09-29 WO PCT/US2017/054237 patent/WO2018064444A1/en active Application Filing
- 2017-09-29 AU AU2017336806A patent/AU2017336806B2/en active Active
- 2017-09-29 CU CU2019000030A patent/CU24660B1/es unknown
- 2017-09-29 IL IL265623A patent/IL265623B2/en unknown
- 2017-09-29 KR KR1020197012456A patent/KR102608081B1/ko active IP Right Grant
- 2017-09-29 NZ NZ752348A patent/NZ752348A/en unknown
- 2017-09-29 CN CN201780060834.3A patent/CN109789198B/zh active Active
- 2017-09-29 EP EP17784755.5A patent/EP3518965A1/en active Pending
- 2017-09-29 CA CA3037056A patent/CA3037056A1/en active Pending
- 2017-09-29 UA UAA201904547A patent/UA126385C2/uk unknown
- 2017-09-29 IL IL297575A patent/IL297575B2/en unknown
- 2017-09-29 EA EA201990838A patent/EA201990838A1/ru unknown
-
2019
- 2019-02-25 ZA ZA2019/01170A patent/ZA201901170B/en unknown
- 2019-03-14 SA SA519401317A patent/SA519401317B1/ar unknown
- 2019-03-27 CO CONC2019/0002955A patent/CO2019002955A2/es unknown
- 2019-03-28 PH PH12019500672A patent/PH12019500672A1/en unknown
- 2019-03-29 US US16/369,933 patent/US11547752B2/en active Active
- 2019-03-29 CL CL2019000849A patent/CL2019000849A1/es unknown
-
2022
- 2022-05-02 JP JP2022076109A patent/JP7403576B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
JP7403576B2 (ja) | 2023-12-22 |
JP2019529497A (ja) | 2019-10-17 |
CL2019000849A1 (es) | 2019-09-23 |
CN109789198A (zh) | 2019-05-21 |
ZA201901170B (en) | 2024-08-28 |
AU2017336806A1 (en) | 2019-05-02 |
US20190224295A1 (en) | 2019-07-25 |
JP2022105155A (ja) | 2022-07-12 |
MX2019003593A (es) | 2019-06-10 |
WO2018064444A1 (en) | 2018-04-05 |
AU2017336806A8 (en) | 2019-05-16 |
EA201990838A1 (ru) | 2019-08-30 |
NZ752348A (en) | 2022-11-25 |
AU2017336806B2 (en) | 2024-06-27 |
EP3518965A1 (en) | 2019-08-07 |
KR102608081B1 (ko) | 2023-11-29 |
IL297575B1 (en) | 2023-08-01 |
BR112019006278A2 (pt) | 2019-07-02 |
UA126385C2 (uk) | 2022-09-28 |
PH12019500672A1 (en) | 2019-07-29 |
IL265623A (en) | 2019-05-30 |
US11547752B2 (en) | 2023-01-10 |
SA519401317B1 (ar) | 2023-11-14 |
IL297575A (en) | 2022-12-01 |
CA3037056A1 (en) | 2018-04-05 |
CU24660B1 (es) | 2023-05-11 |
KR20190066032A (ko) | 2019-06-12 |
CN109789198B (zh) | 2024-08-16 |
CO2019002955A2 (es) | 2019-06-11 |
IL297575B2 (en) | 2023-12-01 |
IL265623B (en) | 2022-12-01 |
IL265623B2 (en) | 2023-04-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CU20190030A7 (es) | Composiciones de vacunas antineumocócicas polivalentes que comprenden conjugados de polisacárido-proteína | |
BR112020004396A8 (pt) | Polissacarídeos pneumocócicos e uso dos mesmos em conjugados imunogênicos polissacarídeo-proteína carreadora | |
BR112020004502A8 (pt) | Polissacarídeos pneumocócicos e uso dos mesmos em conjugados imunogênicos polissacarídeo-proteína carreadora | |
ECSP20032085A (es) | Composiciones que comprenden conjugados de polisacárido de streptococcus pneumoniae con proteína y métodos de uso de estos | |
BR112020004509A8 (pt) | Conjugado polissacarídeo-proteína carreadora, composição imunogênica compreendendo o mesmo e uso do referido conjugado | |
BR112020004471A8 (pt) | Polissacarídeos pneumocócicos e uso dos mesmos em conjugados imunogênicos polissacarídeo-proteína carreadora | |
CO2017011245A2 (es) | Conjugados proteína-polisacárido de estreptococo grupo b, métodos para producir conjugados, composiciones inmunógenas que comprenden conjugados y sus usos | |
PE20211888A1 (es) | Composiciones que comprenden conjugados de polisacarido de streptococcus pneumoniae con proteina y sus metodos de uso | |
BR112018007812A2 (pt) | polissacarídeo capsular, processo para preparar um polissacarídeo capsular e para fabricar uma vacina, composição imunogênica, vacina, métodos para tratamento ou prevenção de uma infecção, para imunizar um hospedeiro humano e para induzir uma resposta imune, e, uso de uma composição imunogênica. | |
CO7240387A2 (es) | Composición conjugada de polisacáridos-proteínas neumocócica polivalente | |
CO7461130A2 (es) | Composición multivalente de conjugados de proteína-polisacárido neumococico | |
AR092897A1 (es) | Composiciones inmunogenicas | |
BR112016015422A2 (pt) | formulações de vacina de frasco único | |
CO2021007863A2 (es) | Vacuna conjugada polisacárido-proteína neumocócica multivalente | |
AR088907A1 (es) | Vacuna | |
BR112019004303A2 (pt) | composição de conjugados multivalentes de polissacarídeo capsular pneumocócico-proteína portadora e uso da mesma | |
AR095425A1 (es) | Vacuna, uso y procedimiento para prevenir una infección por picornavirus | |
AR104514A1 (es) | Conjugados proteína-polisacárido de estreptococo grupo b, métodos para producir conjugados, composiciones inmunógenas que comprenden conjugados y sus usos |