CO4890846A1 - Pirroles sustituidos - Google Patents

Pirroles sustituidos

Info

Publication number
CO4890846A1
CO4890846A1 CO97042577A CO97042577A CO4890846A1 CO 4890846 A1 CO4890846 A1 CO 4890846A1 CO 97042577 A CO97042577 A CO 97042577A CO 97042577 A CO97042577 A CO 97042577A CO 4890846 A1 CO4890846 A1 CO 4890846A1
Authority
CO
Colombia
Prior art keywords
substituted pyrroles
formula
compound
pharmaceutically acceptable
pyrroles
Prior art date
Application number
CO97042577A
Other languages
English (en)
Inventor
Hooda Dhingra Urvashi
Donna Mary Huryn
Dennis Dalton Keith
Giuseppe Federico Weber
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CO4890846A1 publication Critical patent/CO4890846A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Un compuesto de la fórmula:en la que R es alquilo, alquiltio o hidroxi o un producto previo de síntesis del compuesto de la fórmula I farmacéuticamente aceptable o sales farmacéuticamente aceptables de los compuestos de la fórmula I.
CO97042577A 1996-07-29 1997-07-25 Pirroles sustituidos CO4890846A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2208096P 1996-07-29 1996-07-29

Publications (1)

Publication Number Publication Date
CO4890846A1 true CO4890846A1 (es) 2000-02-28

Family

ID=21807715

Family Applications (1)

Application Number Title Priority Date Filing Date
CO97042577A CO4890846A1 (es) 1996-07-29 1997-07-25 Pirroles sustituidos

Country Status (18)

Country Link
US (1) US5891901A (es)
EP (1) EP0915871B1 (es)
JP (1) JP2000516590A (es)
KR (1) KR20000029627A (es)
CN (1) CN1077572C (es)
AR (1) AR007970A1 (es)
AT (1) ATE347551T1 (es)
AU (1) AU739704B2 (es)
BR (1) BR9710902A (es)
CA (1) CA2262088A1 (es)
CO (1) CO4890846A1 (es)
DE (1) DE69737060D1 (es)
HR (1) HRP970417A2 (es)
MA (1) MA24288A1 (es)
PE (1) PE91498A1 (es)
TR (1) TR199900153T2 (es)
WO (1) WO1998004553A1 (es)
ZA (1) ZA976487B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69909068T2 (de) * 1998-03-17 2004-05-06 F. Hoffmann-La Roche Ag Substituierte bisindolylmaleimide zur inhibierung der zellproliferation
US6521658B1 (en) * 1999-05-28 2003-02-18 Abbott Laboratories Cell proliferation inhibitors
US6313143B1 (en) * 1999-12-16 2001-11-06 Hoffmann-La Roche Inc. Substituted pyrroles
US6281356B1 (en) * 1999-12-22 2001-08-28 Hoffmann-La Roche Inc. Substituted pyrroles
US6326501B1 (en) * 2000-04-19 2001-12-04 Hoffmann-La Roche Inc. Methylation of indole compounds using dimethyl carbonate
TWI335221B (en) 2001-09-27 2011-01-01 Alcon Inc Inhibtors of glycogen synthase kinase-3 (gsk-3) for treating glaucoma
WO2005052193A2 (en) * 2003-11-19 2005-06-09 Applera Corporation Methods for determining the degradation state or concentration of nucleic acids
EP3169337A1 (en) 2014-07-17 2017-05-24 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for treating neuromuscular junction-related diseases
WO2016207366A1 (en) 2015-06-26 2016-12-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of viral infections
WO2019000224A1 (zh) * 2017-06-27 2019-01-03 中国海洋大学 双吲哚马来酰亚胺衍生物及其制备方法和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ280738B6 (cs) * 1988-02-10 1996-04-17 F. Hoffmann - La Roche And Co., Aktiengesellschaft Substituované pyrroly, jejich použití pro výrobu léčiv a léčiva na jejich bázi
IL94274A0 (en) * 1989-05-05 1991-03-10 Goedecke Ag Maleinimide derivatives,process for the preparation thereof and pharmaceutical compositions containing the same
US5380746A (en) * 1989-05-05 1995-01-10 Goedecke Aktiengesellschaft Bis-(1H-indol-3-YL)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
JPH0539289A (ja) * 1991-02-15 1993-02-19 Masahiro Irie 無水マレイン酸誘導体およびその製造方法
AU3761393A (en) * 1992-03-20 1993-10-21 Wellcome Foundation Limited, The Indole derivatives with antiviral activity
DE4217964A1 (de) * 1992-05-30 1993-12-02 Goedecke Ag Indolocarbazol-Imide und deren Verwendung

Also Published As

Publication number Publication date
MA24288A1 (fr) 1998-04-01
CN1226249A (zh) 1999-08-18
ZA976487B (en) 1998-01-29
ATE347551T1 (de) 2006-12-15
AU739704B2 (en) 2001-10-18
AR007970A1 (es) 1999-11-24
BR9710902A (pt) 1999-08-17
CN1077572C (zh) 2002-01-09
EP0915871A1 (en) 1999-05-19
HRP970417A2 (en) 1998-08-31
EP0915871B1 (en) 2006-12-06
TR199900153T2 (xx) 1999-04-21
CA2262088A1 (en) 1998-02-05
AU4296497A (en) 1998-02-20
KR20000029627A (ko) 2000-05-25
PE91498A1 (es) 1998-12-22
JP2000516590A (ja) 2000-12-12
DE69737060D1 (de) 2007-01-18
WO1998004553A1 (en) 1998-02-05
US5891901A (en) 1999-04-06

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