CN104258793B - A kind of preparation method of alanine capsule of nano - Google Patents
A kind of preparation method of alanine capsule of nano Download PDFInfo
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- CN104258793B CN104258793B CN201410477076.3A CN201410477076A CN104258793B CN 104258793 B CN104258793 B CN 104258793B CN 201410477076 A CN201410477076 A CN 201410477076A CN 104258793 B CN104258793 B CN 104258793B
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
- B01J13/043—Drying and spraying
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- Chemical Kinetics & Catalysis (AREA)
- General Preparation And Processing Of Foods (AREA)
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Abstract
The invention belongs to microcapsules field, disclose a kind of alanine capsule of nano, described alanine capsule of nano is made up of according to percentage by weight following composition: alanine is 7wt%-19wt%, soybean lecithin is 11wt%-14wt%, Arabic gum 15wt%-21wt%, beeswax are 8wt%-13wt%, polyvinyl alcohol is 2wt%-5wt%, surplus is cyclodextrin.Preparation method's step is as follows: (1) gets core alanine and soybean lecithin, takes alanine, soybean lecithin, carries out emulsification after alanine and soybean lecithin being heated lower dissolving with emulsifying mixer; (2) Arabic gum, beeswax, polyvinyl alcohol is got, cyclodextrin, raw material is soluble in water; (3) by core and wall material aqueous solution, after mixing, homogeneous is carried out with homogenizer; (4) after homogeneous, the aqueous solution of mixing is carried out spraying dry, collect and obtain alanine capsule of nano.
Description
Technical field
The invention belongs to microcapsules field, relate to a kind of preparation method of microcapsules, particularly relate to a kind of preparation method of alanine capsule of nano.
Background technology
Alanine is the base unit forming protein, is one of 21 seed amino acids of composition human body protein.Its molecular formula is C
3h
7o
2n, has α-alanine and Beta-alanine two kinds of isomers.Alanine manufactures vitamin B6, synthetic pantothenic acid calcium and other organic compound raw materials.Make an addition to the seasoning effect that can strengthen chemical seasoning in food, improve sense of taste and the organic acid tart flavour of sweetener, improve the quality containing alcoholic beverage, prevent oil oxidation and improve infusion of food local flavor etc.Also can be used as biochemical reagents, for biochemistry and microbe research aspect.
Microcapsules refer to a certain object completely coated with various macromolecular compound continuous film that is natural or synthesis; and original chemical property of object at all be can't harm; then little by little by some outside stimulus or slow releasing function, the function of object is presented in outside again, or rely on the shielding action of cyst wall to play the effect of protection core.
By less for the report that alanine preparation becomes microcapsules, therefore need to develop a kind of alanine microcapsules, expand the application of alanine.
Summary of the invention
The technical problem solved: alanine is as a kind of important amino acid, there is purposes much more very, but due to its fixing physical property, limit its application in some incompatible fields, if using alanine as microcapsules, then can expand the application approach of alanine.
Technical scheme: for the problems referred to above, the invention discloses a kind of alanine capsule of nano, described alanine capsule of nano is made up of according to percentage by weight following composition: alanine is 7wt%-19wt%, soybean lecithin is 11wt%-14wt%, Arabic gum 15wt%-21wt%, beeswax are 8wt%-13wt%, polyvinyl alcohol is 2wt%-5wt%, surplus is cyclodextrin.
A preparation method for alanine capsule of nano, preparation method's step of described alanine capsule of nano is as follows:
(1) get core alanine and soybean lecithin, take alanine, soybean lecithin, carry out emulsification with emulsifying mixer after alanine and soybean lecithin being heated lower dissolving, after emulsification, core is for subsequent use;
(2) Arabic gum, beeswax, polyvinyl alcohol is got, cyclodextrin, raw material is soluble in water, be the wall material aqueous solution after mixing;
(3) by core and wall material aqueous solution, after mixing, homogeneous is carried out with homogenizer;
(4) after homogeneous, the aqueous solution of mixing is carried out spraying dry, collect and obtain alanine capsule of nano.
Preferably, the preparation method of described a kind of alanine capsule of nano, preparation method's step is as follows:
(1) get core alanine and soybean lecithin, take that alanine is 7g-19g, soybean lecithin is 11g-14g, carry out emulsification with emulsifying mixer after dissolving at alanine and soybean lecithin are heated to 65 DEG C, after emulsification, core is for subsequent use;
(2) get that Arabic gum is 15g-21g, beeswax is 8g-13g, polyvinyl alcohol is 2g-5g, cyclodextrin is 28g-57g, is dissolved in by above-mentioned raw materials in 200g-320g water, is the wall material aqueous solution after mixing;
(3) by core and wall material aqueous solution, carry out homogeneous after mixing with homogenizer, homogenization pressure is 70MPa-90MPa, and homogenizing temperature is 45 DEG C, and homogenizing time is 30-60min;
(4) after homogeneous, the aqueous solution of mixing is carried out spraying dry, spray drying parameters is as follows: EAT is 130 DEG C, and leaving air temp is 90 DEG C, collects and obtains alanine capsule of nano.
Preferably, the preparation method of described a kind of alanine capsule of nano, cyclodextrin is beta-schardinger dextrin-.
Preferably, the preparation method of described a kind of alanine capsule of nano, the spray dryer used is mini spray dryer.
Beneficial effect: alanine is as a kind of common amino acid, application about its microcapsules is less, preparation method of the present invention has prepared the microcapsules of alanine, the core used in preparation method and wall material are the raw material being easy to prepare, and the alanine capsule of nano embedding rate prepared reaches 86.3% to 91.2%.
Detailed description of the invention
Embodiment 1
(1) get core alanine and soybean lecithin, take that alanine is 12g, soybean lecithin is 13g, carry out emulsification with emulsifying mixer after dissolving at alanine and soybean lecithin are heated to 65 DEG C, after emulsification, core is for subsequent use;
(2) get that Arabic gum is 17g, beeswax is 9g, polyvinyl alcohol is 4g, cyclodextrin is 45g, is dissolved in by above-mentioned raw materials in 270g water, is the wall material aqueous solution after mixing;
(3) by core and wall material aqueous solution, carry out homogeneous after mixing with homogenizer, homogenization pressure is 80MPa, and homogenizing temperature is 45 DEG C, and homogenizing time is 60min;
(4) after homogeneous, the aqueous solution of mixing is carried out spraying dry, spray drying parameters is as follows: EAT is 130 DEG C, and leaving air temp is 90 DEG C, collects and obtains alanine capsule of nano.
Embodiment 2
(1) get core alanine and soybean lecithin, take that alanine is 7g, soybean lecithin is 14g, carry out emulsification with emulsifying mixer after dissolving at alanine and soybean lecithin are heated to 65 DEG C, after emulsification, core is for subsequent use;
(2) get that Arabic gum is 15g, beeswax is 13g, polyvinyl alcohol is 2g, cyclodextrin is 49g, is dissolved in by above-mentioned raw materials in 320g water, is the wall material aqueous solution after mixing;
(3) by core and wall material aqueous solution, carry out homogeneous after mixing with homogenizer, homogenization pressure is 90MPa, and homogenizing temperature is 45 DEG C, and homogenizing time is 30min;
(4) after homogeneous, the aqueous solution of mixing is carried out spraying dry, spray drying parameters is as follows: EAT is 130 DEG C, and leaving air temp is 90 DEG C, collects and obtains alanine capsule of nano.
Embodiment 3
(1) get core alanine and soybean lecithin, take that alanine is 19g, soybean lecithin is 11g, carry out emulsification with emulsifying mixer after dissolving at alanine and soybean lecithin are heated to 65 DEG C, after emulsification, core is for subsequent use;
(2) get that Arabic gum is 21g, beeswax is 8g, polyvinyl alcohol is 5g, cyclodextrin is 36g, is dissolved in by above-mentioned raw materials in 200g water, is the wall material aqueous solution after mixing;
(3) by core and wall material aqueous solution, carry out homogeneous after mixing with homogenizer, homogenization pressure is 70MPa, and homogenizing temperature is 45 DEG C, and homogenizing time is 60min;
(4) after homogeneous, the aqueous solution of mixing is carried out spraying dry, spray drying parameters is as follows: EAT is 130 DEG C, and leaving air temp is 90 DEG C, collects and obtains alanine capsule of nano.
The embedding rate of the alanine microcapsules of embodiment 1 to 3 is as follows:
| Embodiment 1 | Embodiment 2 | Embodiment 3 | |
| Embedding rate | 91.2% | 86.3% | 89.8% |
The embedding rate of the alanine capsule of nano of embodiment 1 to 4 is all higher, and its particle diameter is also less simultaneously, and form is comparatively unification also, has good embedding effect, effectively expands the application approach of alanine.
Claims (3)
1. a preparation method for alanine capsule of nano, is characterized in that preparation method's step of described alanine capsule of nano is as follows:
(1) get core alanine and soybean lecithin, take that alanine is 7g-19g, soybean lecithin is 11g-14g, carry out emulsification with emulsifying mixer after dissolving at alanine and soybean lecithin are heated to 65 DEG C, after emulsification, core is for subsequent use;
(2) get that Arabic gum is 15g-21g, beeswax is 8g-13g, polyvinyl alcohol is 2g-5g, cyclodextrin is 28g-57g, is dissolved in by above-mentioned raw materials in 200g-320g water, is the wall material aqueous solution after mixing;
(3) by core and wall material aqueous solution, carry out homogeneous after mixing with homogenizer, homogenization pressure is 70MPa-90MPa, and homogenizing temperature is 45 DEG C, and homogenizing time is 30-60min;
(4) after homogeneous, the aqueous solution of mixing is carried out spraying dry, spray drying parameters is as follows: EAT is 130 DEG C, and leaving air temp is 90 DEG C, collects and obtains alanine capsule of nano.
2. the preparation method of a kind of alanine capsule of nano according to claim 1, is characterized in that described preparation method's cyclodextrin is beta-schardinger dextrin-.
3. the preparation method of a kind of alanine capsule of nano according to claim 1, is characterized in that the spray dryer used in described preparation method is mini spray dryer.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105076729A (en) * | 2015-09-16 | 2015-11-25 | 中粮饲料有限公司 | Feed additive microcapsule and preparation method thereof |
| CN105663081B (en) | 2015-12-30 | 2019-08-02 | 大连医诺生物股份有限公司 | Microencapsulation Beta-alanine |
| CN106000247A (en) * | 2016-05-27 | 2016-10-12 | 东莞市联洲知识产权运营管理有限公司 | Natural silk-containing phase change microcapsule and preparation method thereof |
| CN113521028A (en) * | 2021-06-16 | 2021-10-22 | 安徽安力肽生物科技有限公司 | Preparation method of dendrobium powder nano capsule |
| CN113842846A (en) * | 2021-09-28 | 2021-12-28 | 江苏大学 | Preparation method of beta-cyclodextrin/polyvinyl alcohol nano microcapsule |
| CN116508894A (en) * | 2023-04-27 | 2023-08-01 | 宁波大学 | Mud flat shellfish feed additive and preparation method and application thereof |
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| US4898781A (en) * | 1986-11-07 | 1990-02-06 | Showa Denko K.K. | Water-soluble microcapsules |
| CN101921495A (en) * | 2009-06-12 | 2010-12-22 | 中国中化股份有限公司 | Method for preparing lutein oleoresin microcapsule |
| CN103861537A (en) * | 2014-03-20 | 2014-06-18 | 中国热带农业科学院农产品加工研究所 | Preparation method of essential oil microcapsule |
| CN103865650A (en) * | 2014-03-20 | 2014-06-18 | 中国热带农业科学院农产品加工研究所 | Temperature sensibility liquor-fragrance essence microcapsule for cigarette and preparation method thereof |
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- 2014-09-18 CN CN201410477076.3A patent/CN104258793B/en not_active Expired - Fee Related
Patent Citations (4)
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|---|---|---|---|---|
| US4898781A (en) * | 1986-11-07 | 1990-02-06 | Showa Denko K.K. | Water-soluble microcapsules |
| CN101921495A (en) * | 2009-06-12 | 2010-12-22 | 中国中化股份有限公司 | Method for preparing lutein oleoresin microcapsule |
| CN103861537A (en) * | 2014-03-20 | 2014-06-18 | 中国热带农业科学院农产品加工研究所 | Preparation method of essential oil microcapsule |
| CN103865650A (en) * | 2014-03-20 | 2014-06-18 | 中国热带农业科学院农产品加工研究所 | Temperature sensibility liquor-fragrance essence microcapsule for cigarette and preparation method thereof |
Non-Patent Citations (1)
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| 食品成分微胶囊制备技术及发展趋势展望;孙兰萍 等;《农产品加工·学刊》;20080531(第5期);12-17 * |
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