CL2008003827A1 - Composicion para tabletas de desintegracion oral que comprende al menos una droga ( temazepam), 0,5-3% de un polimero aglutinanete para odt, un alcohol de azucar y/o sacarido, y un desintegrante; metodo para prepararla; util para tratar una enfermedad o condicion como un trastorno del sueño en pacientes con disfagia.. - Google Patents
Composicion para tabletas de desintegracion oral que comprende al menos una droga ( temazepam), 0,5-3% de un polimero aglutinanete para odt, un alcohol de azucar y/o sacarido, y un desintegrante; metodo para prepararla; util para tratar una enfermedad o condicion como un trastorno del sueño en pacientes con disfagia..Info
- Publication number
- CL2008003827A1 CL2008003827A1 CL2008003827A CL2008003827A CL2008003827A1 CL 2008003827 A1 CL2008003827 A1 CL 2008003827A1 CL 2008003827 A CL2008003827 A CL 2008003827A CL 2008003827 A CL2008003827 A CL 2008003827A CL 2008003827 A1 CL2008003827 A1 CL 2008003827A1
- Authority
- CL
- Chile
- Prior art keywords
- temazepam
- composition
- odt
- dysphagia
- disintegrant
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Anesthesiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Composiciones de temazepam para tabletas de desintegración oral y procedimiento de preparación de la composición.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1593107P | 2007-12-21 | 2007-12-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2008003827A1 true CL2008003827A1 (es) | 2009-07-24 |
Family
ID=40798736
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2008003827A CL2008003827A1 (es) | 2007-12-21 | 2008-12-19 | Composicion para tabletas de desintegracion oral que comprende al menos una droga ( temazepam), 0,5-3% de un polimero aglutinanete para odt, un alcohol de azucar y/o sacarido, y un desintegrante; metodo para prepararla; util para tratar una enfermedad o condicion como un trastorno del sueño en pacientes con disfagia.. |
Country Status (10)
Country | Link |
---|---|
US (1) | US20090169620A1 (es) |
KR (1) | KR20100103844A (es) |
CN (2) | CN105496978A (es) |
AR (1) | AR069875A1 (es) |
BR (1) | BRPI0821761A2 (es) |
CL (1) | CL2008003827A1 (es) |
CO (1) | CO6280465A2 (es) |
CR (1) | CR11581A (es) |
RU (2) | RU2524638C2 (es) |
WO (1) | WO2009086046A1 (es) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9387167B2 (en) | 2009-10-01 | 2016-07-12 | Adare Pharmaceuticals, Inc. | Orally administered corticosteroid compositions |
US10471071B2 (en) | 2013-09-06 | 2019-11-12 | Adare Pharmaceuticals, Inc. | Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis |
US11026887B2 (en) | 2016-08-18 | 2021-06-08 | Ellodi Pharmaceuticals, L.P. | Methods of treating eosinophilic esophagitis |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8497258B2 (en) | 2005-11-12 | 2013-07-30 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
EP2328558A2 (en) * | 2008-08-08 | 2011-06-08 | McNeil-PPC, Inc. | Use of sucralose as a granulating agent |
EP2435052B1 (en) * | 2009-05-27 | 2015-07-15 | Hetero Research Foundation | Solid oral dosage forms of lamivudine with isomalt |
WO2010144865A2 (en) | 2009-06-12 | 2010-12-16 | Meritage Pharma, Inc. | Methods for treating gastrointestinal disorders |
US9273049B2 (en) * | 2009-11-10 | 2016-03-01 | North-West University | Method for increasing the solubility of nevirapine |
SG10201407947WA (en) * | 2009-11-30 | 2015-01-29 | Aptalis Pharmatech Inc | Compressible-coated pharmaceutical compositions and tablets and methods of manufacture |
SG184851A1 (en) * | 2010-04-27 | 2012-11-29 | Bayer Ip Gmbh | Orally disintegrating tablet containing acarbose |
US20120282335A1 (en) * | 2010-12-02 | 2012-11-08 | Aptalis Pharmatech Inc. | Rapidly dispersing granules, orally disintegrating tablets and methods |
RU2013150323A (ru) * | 2011-05-02 | 2015-06-10 | Апталис Фарматек, Инк. | Композиции в форме быстрорастворимых таблеток для вагинального введения |
KR101285008B1 (ko) * | 2012-04-18 | 2013-07-10 | 제일약품주식회사 | 저용량 엔테카비어의 경구투여 제제의 제조방법 |
CN102784117A (zh) * | 2012-08-23 | 2012-11-21 | 海南卫康制药(潜山)有限公司 | 硫酸庆大霉素组合物冻干口腔崩解片及其制备方法 |
CN102784121A (zh) * | 2012-08-23 | 2012-11-21 | 海南卫康制药(潜山)有限公司 | 左氧氟沙星组合物冻干口腔崩解片及其制备方法 |
CN102784126A (zh) * | 2012-08-23 | 2012-11-21 | 海南卫康制药(潜山)有限公司 | 利福平组合物冻干口腔崩解片及其制备方法 |
GR1008992B (el) * | 2015-12-17 | 2017-03-23 | Verisfield (Uk) Ltd, Υποκαταστημα Ελλαδας, Εμπορια Φαρμακων | Φαρμακευτικη συνθεση σε μορφη κοκκιων για χορηγηση απο το στομα που περιεχει μετρονιδαζολη ή παραγωγα αυτης και εναν παραγοντα καλυψης της γευσης |
US20180256515A1 (en) | 2017-03-10 | 2018-09-13 | Adare Pharmaceuticals, Inc. | Oral amphetamine composition |
EP3612166A4 (en) | 2017-04-20 | 2020-11-04 | Zeenar Enterprises Pty Ltd | LIQUID CRYSTAL GALENIC FORM FOR THE ADMINISTRATION OF STATIN |
SG11202007226UA (en) | 2018-01-30 | 2020-08-28 | Apnimed Inc Delaware | Methods and compositions for treating sleep apnea |
CN110840850B (zh) * | 2018-07-24 | 2023-03-17 | 烟台药物研究所 | 一种高生物利用度的塞来昔布冻干口崩片及其制备方法 |
US20210369623A1 (en) * | 2018-10-25 | 2021-12-02 | Zeenar Enterprises Pty Ltd | Composition that forms liquid crystalline particles |
EA202192202A1 (ru) * | 2019-02-08 | 2021-11-03 | Дзе Брихэм Энд Уимен'З Хоспитал, Инк. | Способы и композиции для лечения синдрома обструктивного апноэ, возникающего во сне |
FR3099881B1 (fr) | 2019-08-13 | 2022-08-26 | Ethypharm Sa | Comprimé orodispersible d’opioide à faible dosage et son procédé de préparation. |
CN110742868A (zh) * | 2019-11-20 | 2020-02-04 | 合肥拓锐生物科技有限公司 | 一种Mirogabalin Besilate口腔崩解片 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4662880A (en) * | 1986-03-14 | 1987-05-05 | Alza Corporation | Pseudoephedrine, brompheniramine therapy |
US5629310A (en) * | 1986-09-23 | 1997-05-13 | Sterling; William R. | Low dose temazepam |
EP1121103B1 (en) * | 1998-05-18 | 2006-12-20 | Takeda Pharmaceutical Company Limited | Orally disintegrable tablets comprising a benzimidazole |
EP1620075B1 (en) * | 2003-05-07 | 2020-06-24 | Samyang Biopharmaceuticals Corporation | Highly plastic granules for making fast melting tablets |
GB0420016D0 (en) * | 2004-09-09 | 2004-10-13 | Leuven K U Res & Dev | Controlled release oral delivery system |
US20060105038A1 (en) * | 2004-11-12 | 2006-05-18 | Eurand Pharmaceuticals Limited | Taste-masked pharmaceutical compositions prepared by coacervation |
WO2006133349A2 (en) * | 2005-06-08 | 2006-12-14 | Alpharma, Inc. | Orally disintegrable sleep aid formulations |
CN103211779B (zh) * | 2006-01-27 | 2016-03-16 | 阿代尔制药股份有限公司 | 包含弱碱性选择性5-羟色胺5-ht3阻断剂和有机酸的药物递送系统 |
-
2008
- 2008-12-19 RU RU2010130340/15A patent/RU2524638C2/ru not_active IP Right Cessation
- 2008-12-19 CN CN201510958509.1A patent/CN105496978A/zh active Pending
- 2008-12-19 BR BRPI0821761-0A patent/BRPI0821761A2/pt not_active IP Right Cessation
- 2008-12-19 US US12/339,908 patent/US20090169620A1/en not_active Abandoned
- 2008-12-19 WO PCT/US2008/087583 patent/WO2009086046A1/en active Application Filing
- 2008-12-19 AR ARP080105625A patent/AR069875A1/es unknown
- 2008-12-19 KR KR1020107016364A patent/KR20100103844A/ko active IP Right Grant
- 2008-12-19 CN CN2008801252464A patent/CN101925349A/zh active Pending
- 2008-12-19 CL CL2008003827A patent/CL2008003827A1/es unknown
-
2010
- 2010-07-16 CO CO10087094A patent/CO6280465A2/es not_active Application Discontinuation
- 2010-07-21 CR CR11581A patent/CR11581A/es not_active Application Discontinuation
-
2014
- 2014-02-24 RU RU2014106871/15A patent/RU2014106871A/ru not_active Application Discontinuation
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9387167B2 (en) | 2009-10-01 | 2016-07-12 | Adare Pharmaceuticals, Inc. | Orally administered corticosteroid compositions |
US9849084B2 (en) | 2009-10-01 | 2017-12-26 | Adare Pharmaceuticals, Inc. | Orally administered corticosteroid compositions |
US11266598B2 (en) | 2009-10-01 | 2022-03-08 | Ellodi Pharmaceuticals, L.P. | Orally administered corticosteroid compositions |
US10471071B2 (en) | 2013-09-06 | 2019-11-12 | Adare Pharmaceuticals, Inc. | Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis |
US11166961B2 (en) | 2013-09-06 | 2021-11-09 | Ellodi Pharmaceuticals, L.P. | Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis |
US11260061B2 (en) | 2013-09-06 | 2022-03-01 | Ellodi Pharmaceuticals, L.P. | Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis |
US11026887B2 (en) | 2016-08-18 | 2021-06-08 | Ellodi Pharmaceuticals, L.P. | Methods of treating eosinophilic esophagitis |
US11684571B2 (en) | 2016-08-18 | 2023-06-27 | Ellodi Pharmaceuticals, L.P. | Methods of treating eosinophilic esophagitis |
US11896710B2 (en) | 2016-08-18 | 2024-02-13 | Ellodi Pharmaceuticals, L.P. | Methods of treating eosinophilic esophagitis |
Also Published As
Publication number | Publication date |
---|---|
RU2014106871A (ru) | 2015-08-27 |
RU2010130340A (ru) | 2012-01-27 |
CN105496978A (zh) | 2016-04-20 |
US20090169620A1 (en) | 2009-07-02 |
AR069875A1 (es) | 2010-02-24 |
CO6280465A2 (es) | 2011-05-20 |
BRPI0821761A2 (pt) | 2015-06-16 |
KR20100103844A (ko) | 2010-09-28 |
CR11581A (es) | 2010-10-11 |
CN101925349A (zh) | 2010-12-22 |
WO2009086046A1 (en) | 2009-07-09 |
RU2524638C2 (ru) | 2014-07-27 |
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