CH539012A - Verfahren zur Herstellung neuer Phenoxyalkancarbonsäuren - Google Patents

Verfahren zur Herstellung neuer Phenoxyalkancarbonsäuren

Info

Publication number
CH539012A
CH539012A CH567770A CH567770A CH539012A CH 539012 A CH539012 A CH 539012A CH 567770 A CH567770 A CH 567770A CH 567770 A CH567770 A CH 567770A CH 539012 A CH539012 A CH 539012A
Authority
CH
Switzerland
Prior art keywords
new
production
phenoxyalkanecarboxylic acids
phenoxyalkanecarboxylic
acids
Prior art date
Application number
CH567770A
Other languages
English (en)
Inventor
Nakamura Yasushi
Agatsuma Kunio
Tanaka Yoshihiro
Aono Shunji
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2990569A external-priority patent/JPS5010298B1/ja
Priority claimed from JP2990769A external-priority patent/JPS5010299B1/ja
Priority claimed from JP8004269A external-priority patent/JPS5010308B1/ja
Priority claimed from JP10419469A external-priority patent/JPS4939995B1/ja
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Priority claimed from US00206966A external-priority patent/US3821404A/en
Publication of CH539012A publication Critical patent/CH539012A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH567770A 1969-04-16 1970-04-16 Verfahren zur Herstellung neuer Phenoxyalkancarbonsäuren CH539012A (de)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
JP2990569A JPS5010298B1 (de) 1969-04-16 1969-04-16
JP2990769A JPS5010299B1 (de) 1969-04-16 1969-04-16
JP3416769 1969-05-02
JP3416669 1969-05-02
JP8004269A JPS5010308B1 (de) 1969-10-03 1969-10-03
JP8004169 1969-10-03
JP10280969 1969-12-19
JP10419469A JPS4939995B1 (de) 1969-12-23 1969-12-23
US2641270A 1970-04-07 1970-04-07
US00206966A US3821404A (en) 1969-04-16 1971-12-10 Phenoxy carboxylic acid derivatives as anti-atherosclerosis agents

Publications (1)

Publication Number Publication Date
CH539012A true CH539012A (de) 1973-08-31

Family

ID=27579824

Family Applications (2)

Application Number Title Priority Date Filing Date
CH748073A CH556807A (de) 1969-04-16 1970-04-16 Verfahren zur herstellung neuer phenoxyalkancarbonsaeuren und ester derselben.
CH567770A CH539012A (de) 1969-04-16 1970-04-16 Verfahren zur Herstellung neuer Phenoxyalkancarbonsäuren

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH748073A CH556807A (de) 1969-04-16 1970-04-16 Verfahren zur herstellung neuer phenoxyalkancarbonsaeuren und ester derselben.

Country Status (9)

Country Link
US (2) US3716583A (de)
AT (2) AT302278B (de)
BE (1) BE748970A (de)
CA (1) CA964273A (de)
CH (2) CH556807A (de)
DK (1) DK128731B (de)
FI (1) FI52570C (de)
FR (1) FR2042333B1 (de)
NL (1) NL139016B (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
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US4008265A (en) * 1971-05-22 1977-02-15 Sumitomo Chemical Company, Limited Novel bisphenoxy carboxylic acid derivatives and their salts
US4092324A (en) * 1971-05-22 1978-05-30 Sumitomo Chemical Company, Limited Diheterocyclic esters of 4-(1,1-bis-(phenoxy-propionic or -butoyric acid)-cyclohexane)α-methyl substituted
JPS575214B2 (de) * 1972-06-01 1982-01-29
JPS4931651A (de) * 1972-07-20 1974-03-22
JPS5735171B2 (de) * 1973-07-02 1982-07-27
CH617417A5 (de) * 1973-12-27 1980-05-30 Siegfried Ag
AT353776B (de) * 1973-12-27 1979-12-10 Siegfried Ag Verfahren zur herstellung von neuen alkan- saeuren, deren estern und salzen
FR2428629A1 (fr) * 1978-06-14 1980-01-11 Hexachimie Nouveaux composes bis(aryloxycarboxyliques), leur preparation et leur utilisation en therapeutique
EP0363760A1 (de) * 1988-10-12 1990-04-18 Bayer Ag Aromatische Ether
US5179097A (en) * 1991-06-10 1993-01-12 Angres Isaac A Salts of non-steroidal anti-inflammatory carboxylic acids and anti-lipidemic carboxylic acids
US6083497A (en) * 1997-11-05 2000-07-04 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
US6982251B2 (en) * 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
EP1911462A3 (de) 2001-01-26 2011-11-30 Schering Corporation Zusammensetzungen enthaltend einen Sterolabsorptionshemmer
US7071181B2 (en) * 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
CA2434033A1 (en) * 2001-01-26 2002-08-01 Schering Corporation Combinations of bile acid sequestrant(s) and sterol absorption inhibitor(s) and treatments for vascular indications
MY138301A (en) * 2001-01-26 2009-05-29 Schering Corp The use of substituted azetidinone compounds for the treatment of sitosterolemia
WO2002058731A2 (en) * 2001-01-26 2002-08-01 Schering Corporation Combinations of sterol absorption inhibitor(s) with cardiovascular agent(s) for the treatment of vascular conditions
JP2004517916A (ja) * 2001-01-26 2004-06-17 シェーリング　コーポレイション ニコチン酸およびその誘導体ならびにステロール吸収阻害剤の併用、および血管適応症の治療
DK1353696T3 (da) * 2001-01-26 2007-04-10 Schering Corp Kombinationer af peroxisomproliferatoraktiveret receptor (PPAR)-aktivator(er) og sterolabsorptionsinhibitor(er) og behandlinger til vaskulære indikationer
US20060287254A1 (en) * 2001-01-26 2006-12-21 Schering Corporation Use of substituted azetidinone compounds for the treatment of sitosterolemia
PL364178A1 (en) * 2001-01-26 2004-12-13 Schering Corporation Combinations of sterol absorption inhibitor(s) with blood modifier(s) for treating vascular conditions
ATE345792T1 (de) * 2001-05-25 2006-12-15 Schering Corp Verwendung von mit azetidinon substituierten derivaten bei der behandlung der alzheimer- krankheit
CN101785772A (zh) * 2001-09-21 2010-07-28 先灵公司 使用甾醇吸收抑制剂治疗或预防脉管炎的方法
US7056906B2 (en) * 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
DK1429756T3 (da) * 2001-09-21 2007-03-19 Schering Corp Behandling af xanthoma med azetidinonderivater som sterolabsorptionsinhibitorer
US7053080B2 (en) * 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US20030119808A1 (en) * 2001-09-21 2003-06-26 Schering Corporation Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects
JP2006508189A (ja) * 2002-11-06 2006-03-09 シェーリング　コーポレイション 自己免疫障害の処置のためのコレステロール吸収インヒビター
US7459442B2 (en) * 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
MXPA05009502A (es) * 2003-03-07 2005-10-18 Schering Corp Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
MXPA05009501A (es) * 2003-03-07 2005-10-18 Schering Corp Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
WO2004081002A1 (en) * 2003-03-07 2004-09-23 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
UA82698C2 (uk) * 2003-05-30 2008-05-12 Ранбакси Лабораториз Лимитед Заміщені похідні піролу та їх використання в якості інгібіторів hmg-co
US20050096307A1 (en) * 2003-11-05 2005-05-05 Schering Corporation Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions
US6998397B2 (en) * 2004-07-23 2006-02-14 Drebsk Comptech, Inc. Method for decreasing cholesterol level in blood
AU2006313430B2 (en) * 2005-11-08 2012-09-06 Ranbaxy Laboratories Limited Process for (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
AR059838A1 (es) * 2006-03-14 2008-04-30 Ranbaxy Lab Ltd Formulaciones para dosis estabilizantes de estatina
CN101494980A (zh) * 2006-07-14 2009-07-29 兰贝克赛实验室有限公司 HMG-CoA还原酶抑制剂的多晶型形式及其应用
CL2008000684A1 (es) 2007-03-09 2008-08-01 Indigene Pharmaceuticals Inc Composicion farmaceutica que comprende metformina r-(+) lipoato y un inhibidor de reductasa hmg-coa; formulacion de dosis unitaria; y uso en el tratamiento de una complicacion diabetica.
WO2012027331A1 (en) 2010-08-27 2012-03-01 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
KR20170115071A (ko) 2015-02-06 2017-10-16 인터셉트 파마슈티컬즈, 인크. 병용 요법을 위한 약제학적 조성물
CN104610051A (zh) * 2015-03-02 2015-05-13 北京万全德众医药生物技术有限公司 一种制备克利贝特杂质的方法
BR112021024109A2 (pt) 2019-05-30 2022-03-22 Intercept Pharmaceuticals Inc Composições farmacêuticas compreendendo um agonista fxr e um fibrato para uso no tratamento de doença hepática colestática

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2444594A (en) * 1947-08-07 1948-07-06 American Cyanamid Co Isopropylidene-p-phenoxy-2-ethanol-p-phenoxyacetic acid
US2541003A (en) * 1948-08-17 1951-02-06 American Cyanamid Co Process for reacting salts of phenols with halo-alkanoic acid compounds
GB860303A (en) * 1958-06-20 1961-02-01 Ici Ltd Pharmaceutical compositions comprising ª‡-aryloxy-aliphatic carboxylic acids and/or ª
US3169144A (en) * 1960-08-12 1965-02-09 Massarani Elena Anticholesterinemic and antilipaemic agents
GB970969A (en) * 1963-08-15 1964-09-23 Shell Int Research Dicarboxylic acids and their esters and a process for the preparation thereof
FR1380816A (fr) * 1963-11-18 1964-12-04 Ciba Geigy Procédé de préparation de nouveaux acides isobutyriques, entre autres de l'acide alpha-[p-(2-p'-chlorophényl-propyl-[2])-phénoxy]-isobutyrique
US3470234A (en) * 1965-08-23 1969-09-30 Ciba Geigy Corp Diaryl substituted benzocycloalkanes
US3470235A (en) * 1965-11-05 1969-09-30 Eastman Kodak Co Alicyclic bisphenyleneoxydicarboxylic acids,salts and esters
GB1121722A (en) * 1966-03-31 1968-07-31 Ici Ltd New carboxylic acid derivatives
US3630715A (en) * 1968-12-19 1971-12-28 Weston Chemical Corp Alkylene bis (phenoxyacetic acid) derivatives as herbicides
US3755603A (en) * 1970-07-01 1973-08-28 Syntex Corp Biphenylyloxyacetic acids in pharmaceutical compositions

Also Published As

Publication number Publication date
FR2042333B1 (de) 1973-04-06
NL139016B (nl) 1973-06-15
BE748970A (fr) 1970-09-16
FR2042333A1 (de) 1971-02-12
CH556807A (de) 1974-12-13
US3716583A (en) 1973-02-13
FI52570B (de) 1977-06-30
FI52570C (fi) 1977-10-10
US3959484A (en) 1976-05-25
AT302278B (de) 1972-10-10
DK128731B (da) 1974-06-24
NL7005400A (de) 1970-10-20
AT303015B (de) 1972-11-10
CA964273A (en) 1975-03-11

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Legal Events

Date Code Title Description
PL Patent ceased