CA993878A - Asymmetric synthesis of polycyclic organic compounds - Google Patents

Asymmetric synthesis of polycyclic organic compounds

Info

Publication number: CA993878A
Authority: CA; Canada
Prior art keywords: organic compounds; asymmetric synthesis; polycyclic organic; polycyclic; asymmetric
Prior art date: 1970-01-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA103,278A

Other languages

English (en)

Inventor

Zoltan G. Hajos

David R. Parrish

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

F Hoffmann La Roche AG

Original Assignee

F Hoffmann La Roche AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1970-01-21

Filing date

1971-01-21

Publication date

1976-07-27

1971-01-21 Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG

1976-07-27 Application granted granted Critical

1976-07-27 Publication of CA993878A publication Critical patent/CA993878A/en

Status Expired legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
- C07C45/66—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups by dehydration
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/69—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to carbon-to-carbon double or triple bonds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
- C07C45/73—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with hydrogenation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/385—Saturated compounds containing a keto group being part of a ring
- C07C49/487—Saturated compounds containing a keto group being part of a ring containing hydroxy groups
- C07C49/507—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic
- C07C49/513—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Catching Or Destruction (AREA)

CA103,278A 1970-01-21 1971-01-21 Asymmetric synthesis of polycyclic organic compounds Expired CA993878A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US476270A	1970-01-21	1970-01-21

Publications (1)

Publication Number	Publication Date
CA993878A true CA993878A (en)	1976-07-27

Family

ID=27421984

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
CA103,278A Expired CA993878A (en)	1970-01-21	1971-01-21	Asymmetric synthesis of polycyclic organic compounds
CA247,076A Expired CA1013752A (en)	1970-01-21	1976-03-04	Process for the preparation of cycloalkanediones

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
CA247,076A Expired CA1013752A (en)	1970-01-21	1976-03-04	Process for the preparation of cycloalkanediones

Country Status (21)

Country	Link
US (2)	US3975440A (xx)
JP (2)	JPS5737573B1 (xx)
AT (4)	AT308087B (xx)
BE (1)	BE761783A (xx)
CA (2)	CA993878A (xx)
CH (3)	CH588434A5 (xx)
DE (3)	DE2102623C2 (xx)
DK (2)	DK146717C (xx)
ES (2)	ES387449A1 (xx)
FI (2)	FI53450C (xx)
FR (2)	FR2077253B1 (xx)
GB (2)	GB1325632A (xx)
HU (2)	HU166419B (xx)
IE (3)	IE35093B1 (xx)
IL (1)	IL35985A (xx)
NL (2)	NL164267C (xx)
NO (4)	NO134983C (xx)
PH (2)	PH12661A (xx)
SE (2)	SE393798B (xx)
YU (1)	YU35332B (xx)
ZA (1)	ZA7120B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4201869A (en) *	1970-12-21	1980-05-06	Hoffmann-La Roche Inc.	Intermediates for steroid total synthesis process utilizing asymmetric induction
ZA814972B (en) *	1980-07-30	1982-07-28	Beecham Group Plc	Reduced naphthalenes,their preparation and use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2668858A (en) *		1954-02-09		Process for their preparation
US2407673A (en) *	1941-06-20	1946-09-17	Research Corp	Process for the synthesis of 1-keto-8-methylhexahydroindanol-1
US2833694A (en) *	1955-08-25	1958-05-06	Ciba Pharm Prod Inc	Process for splitting racemates
NL130309C (xx) *	1963-11-29
NL131552C (xx) *	1965-04-28
AT278767B (de) *	1965-10-13	1970-02-10	Hoffmann La Roche	Verfahren zur herstellung von neuen indanderivaten
US3501479A (en) *	1967-05-19	1970-03-17	American Cyanamid Co	Dihydroquinolines and substituted dihydroquinolines and method of preparing the same
US3897460A (en) *	1968-10-04	1975-07-29	Hoffmann La Roche	3{62 -Tertiarybutoxy-decahydro-benz{8 E{9 indenes
DE2016750A1 (de) *	1970-04-04	1971-10-14	Schering Ag, 1000 Berlin Und 4619 Bergkamen	Verfahren zur Herstellung von 2,2 disubstituierten Cycloalkan 1,3 dionen

1970
- 1970-12-09 US US05/096,597 patent/US3975440A/en not_active Expired - Lifetime
1971
- 1971-01-04 ZA ZA710020A patent/ZA7120B/xx unknown
- 1971-01-07 CH CH18571A patent/CH588434A5/xx not_active IP Right Cessation
- 1971-01-07 CH CH638775A patent/CH597129A5/xx not_active IP Right Cessation
- 1971-01-10 PH PH12122A patent/PH12661A/en unknown
- 1971-01-12 IL IL35985A patent/IL35985A/xx unknown
- 1971-01-14 IE IE42/71A patent/IE35093B1/xx unknown
- 1971-01-14 IE IE1797/73A patent/IE35095B1/xx unknown
- 1971-01-14 IE IE1796/73A patent/IE35094B1/xx unknown
- 1971-01-19 YU YU117/71A patent/YU35332B/xx unknown
- 1971-01-19 GB GB4688172A patent/GB1325632A/en not_active Expired
- 1971-01-19 GB GB257171A patent/GB1325631A/en not_active Expired
- 1971-01-20 AT AT45571A patent/AT308087B/de active
- 1971-01-20 FI FI152/71A patent/FI53450C/fi active
- 1971-01-20 AT AT392372A patent/AT316533B/de not_active IP Right Cessation
- 1971-01-20 NO NO200/71A patent/NO134983C/no unknown
- 1971-01-20 DE DE2102623A patent/DE2102623C2/de not_active Expired
- 1971-01-20 AT AT392272A patent/AT315142B/de not_active IP Right Cessation
- 1971-01-20 ES ES387449A patent/ES387449A1/es not_active Expired
- 1971-01-20 FR FR717101825A patent/FR2077253B1/fr not_active Expired
- 1971-01-20 DE DE2166994A patent/DE2166994C3/de not_active Expired
- 1971-01-20 BE BE761783A patent/BE761783A/xx not_active IP Right Cessation
- 1971-01-20 DE DE19712166993 patent/DE2166993A1/de active Pending
- 1971-01-21 JP JP177971A patent/JPS5737573B1/ja active Pending
- 1971-01-21 HU HUHO1647A patent/HU166419B/hu unknown
- 1971-01-21 DK DK25571A patent/DK146717C/da not_active IP Right Cessation
- 1971-01-21 CA CA103,278A patent/CA993878A/en not_active Expired
- 1971-01-21 NL NL7100813.A patent/NL164267C/xx not_active IP Right Cessation
- 1971-01-21 HU HUHO1349A patent/HU166411B/hu unknown
- 1971-01-21 SE SE7100704A patent/SE393798B/xx unknown
- 1971-09-08 ES ES394882A patent/ES394882A1/es not_active Expired
- 1971-11-05 FR FR717139725A patent/FR2112170B1/fr not_active Expired
1972
- 1972-05-05 AT AT392472A patent/AT348150B/de not_active IP Right Cessation
- 1972-06-13 NO NO2099/72A patent/NO138000C/no unknown
- 1972-06-13 NO NO2098/72A patent/NO134371C/no unknown
1973
- 1973-12-28 SE SE7317592A patent/SE404607B/xx unknown
1975
- 1975-08-04 PH PH17445A patent/PH11206A/en unknown
1976
- 1976-01-07 CH CH1535676A patent/CH589024A5/xx not_active IP Right Cessation
- 1976-03-04 CA CA247,076A patent/CA1013752A/en not_active Expired
- 1976-03-30 NO NO761104A patent/NO761104L/no unknown
1977
- 1977-05-23 FI FI771632A patent/FI771632A/fi not_active Application Discontinuation
- 1977-11-11 JP JP13556877A patent/JPS5373541A/ja active Granted
1978
- 1978-06-12 US US05/914,840 patent/US4189447A/en not_active Expired - Lifetime
1979
- 1979-07-16 DK DK298479A patent/DK298479A/da not_active Application Discontinuation
- 1979-10-02 NL NL7907334A patent/NL7907334A/nl unknown

Also Published As

Publication number	Publication date
NO134371C (xx)	1976-09-29
FR2112170A1 (xx)	1972-06-16
AT315142B (de)	1974-05-10
NL7100813A (xx)	1971-07-23
PH12661A (en)	1979-07-11
HU166419B (xx)	1975-03-28
IE35094B1 (en)	1975-11-12
SE404607B (sv)	1978-10-16
JPS5373541A (en)	1978-06-30
CH597129A5 (xx)	1978-03-31
GB1325631A (en)	1973-08-08
ZA7120B (en)	1971-10-27
NO761104L (xx)	1971-07-22
IL35985A0 (en)	1971-03-24
FI53450C (fi)	1978-05-10
DE2102623C2 (de)	1982-04-15
IL35985A (en)	1974-05-16
FI771632A (xx)	1977-05-23
JPS5737573B1 (xx)	1982-08-10
YU35332B (en)	1980-12-31
IE35095B1 (en)	1975-11-12
DE2166994A1 (de)	1977-07-14
NL7907334A (nl)	1980-01-31
NL164267C (nl)	1980-12-15
FR2077253B1 (xx)	1973-06-08
FR2112170B1 (xx)	1973-06-29
NL164267B (nl)	1980-07-15
US3975440A (en)	1976-08-17
AT308087B (de)	1973-06-25
AT316533B (de)	1974-07-10
ATA392472A (de)	1978-06-15
HU166411B (xx)	1975-03-28
IE35093L (en)	1971-07-21
AT348150B (de)	1979-01-25
PH11206A (en)	1977-10-28
SE393798B (sv)	1977-05-23
NO138000B (no)	1978-02-27
NO138000C (no)	1978-06-07
DE2102623A1 (xx)	1971-07-29
BE761783A (fr)	1971-07-20
CH588434A5 (xx)	1977-05-31
JPS5546377B2 (xx)	1980-11-22
FI53450B (xx)	1978-01-31
CA1013752A (en)	1977-07-12
DE2166993A1 (de)	1977-07-14
FR2077253A1 (xx)	1971-10-22
ES394882A1 (es)	1974-03-01
NO134983C (xx)	1977-01-26
IE35093B1 (en)	1975-11-12
GB1325632A (en)	1973-08-08
DK298479A (da)	1979-07-16
US4189447A (en)	1980-02-19
NO134371B (xx)	1976-06-21
ES387449A1 (es)	1974-12-16
NO134983B (xx)	1976-10-11
CH589024A5 (xx)	1977-06-30
DK146717B (da)	1983-12-12
DK146717C (da)	1984-05-21
DE2166994B2 (de)	1980-01-31
DE2166994C3 (de)	1980-10-09
YU11771A (en)	1980-06-30

Publication	Publication Date	Title
CA1000943A (en)	1976-12-07	Class of stable trans-stilbene compounds
CA981681A (en)	1976-01-13	Polycyclic compounds
CA1013692A (en)	1977-07-12	Production of 7-amino-3-methylcephem compounds
CA958037A (en)	1974-11-19	Thermal decomposition of organic compounds
AU449139B2 (en)	1974-06-06	Deodorization of organothiophosphorus compounds
AU3418871A (en)	1973-04-12	Organic compounds
CA919701A (en)	1973-01-23	Synthesis of 2,4,6-tri-t-butyl-4-methoxycyclohexa-2,5-dien-1-one
CA993878A (en)	1976-07-27	Asymmetric synthesis of polycyclic organic compounds
AU2843371A (en)	1972-11-09	Novel compounds
AU450446B2 (en)	1972-07-13	Asymmetric synthesis of polycyclic organic compounds
AU3557271A (en)	1973-05-17	Compounds and synthesis
AU2410571A (en)	1972-07-13	Asymmetric synthesis of polycyclic organic compounds
CA931903A (en)	1973-08-14	Synthesis of organonickel compounds
CA936803A (en)	1973-11-13	Organic compounds
AU449714B2 (en)	1972-06-15	Production of tetrasila-adamantane compounds
CA850146A (en)	1970-08-25	Synthesis of halophenylacetophenones
CA937574A (en)	1973-11-27	Synthesis of 1-substituted-2-r-5-nitroimidazoles
CA832011A (en)	1970-01-13	Synthesis of abscisin ii
CA872790A (en)	1971-06-08	Synthesis of adamantane compounds
AU2308470A (en)	1972-06-15	Production of tetrasila-adamantane compounds
CA850082A (en)	1970-08-25	Process for the manufacture of polycyclic compounds
CA859767A (en)	1970-12-29	Process for the manufacture of polycyclic compounds
CA847379A (en)	1970-07-21	Production of compounds of the axerophthylidene series
CA859773A (en)	1970-12-29	Preparation of hexaaryldilead compounds
CA859202A (en)	1970-12-22	Preparation of magnesium-alcohol compounds