BRPI0815003A2 - Uso de um composto, composições, compostos, uso dos mesmos, método de tratamento, melhora ou profilaxia dos sintomas de um distúrbio inflamatório. - Google Patents

Uso de um composto, composições, compostos, uso dos mesmos, método de tratamento, melhora ou profilaxia dos sintomas de um distúrbio inflamatório.

Info

Publication number
BRPI0815003A2
BRPI0815003A2 BRPI0815003-6A2A BRPI0815003A BRPI0815003A2 BR PI0815003 A2 BRPI0815003 A2 BR PI0815003A2 BR PI0815003 A BRPI0815003 A BR PI0815003A BR PI0815003 A2 BRPI0815003 A2 BR PI0815003A2
Authority
BR
Brazil
Prior art keywords
prophylaxis
symptoms
compositions
compounds
improvement
Prior art date
Application number
BRPI0815003-6A2A
Other languages
English (en)
Inventor
David John Grainger
David Fox
Original Assignee
Cambridge Entpr Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38529182&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0815003(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cambridge Entpr Ltd filed Critical Cambridge Entpr Ltd
Publication of BRPI0815003A2 publication Critical patent/BRPI0815003A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/12—Nitrogen atoms not forming part of a nitro radical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • AIDS & HIV (AREA)
  • Otolaryngology (AREA)
BRPI0815003-6A2A 2007-08-02 2008-08-01 Uso de um composto, composições, compostos, uso dos mesmos, método de tratamento, melhora ou profilaxia dos sintomas de um distúrbio inflamatório. BRPI0815003A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0715068A GB2452696B (en) 2007-08-02 2007-08-02 3-(2',2'-dimethylpropanoylamino)-tetrahydropyridin-2-one and its use in pharmaceutical compositions
PCT/GB2008/002635 WO2009016390A1 (en) 2007-08-02 2008-08-01 Anti-inflammatory composition

Publications (1)

Publication Number Publication Date
BRPI0815003A2 true BRPI0815003A2 (pt) 2015-03-03

Family

ID=38529182

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0815003-6A2A BRPI0815003A2 (pt) 2007-08-02 2008-08-01 Uso de um composto, composições, compostos, uso dos mesmos, método de tratamento, melhora ou profilaxia dos sintomas de um distúrbio inflamatório.

Country Status (21)

Country Link
US (2) US8853200B2 (pt)
EP (2) EP2185151B1 (pt)
JP (1) JP5680963B2 (pt)
KR (1) KR20100043258A (pt)
CN (2) CN102973562B (pt)
AU (1) AU2008281570C1 (pt)
BR (1) BRPI0815003A2 (pt)
CA (1) CA2695257A1 (pt)
CY (1) CY1115384T1 (pt)
DK (1) DK2185151T3 (pt)
ES (1) ES2478243T3 (pt)
GB (1) GB2452696B (pt)
HR (1) HRP20140647T1 (pt)
MX (1) MX2010001243A (pt)
NZ (1) NZ583503A (pt)
PL (1) PL2185151T3 (pt)
PT (1) PT2185151E (pt)
RU (1) RU2483730C2 (pt)
SI (1) SI2185151T1 (pt)
WO (1) WO2009016390A1 (pt)
ZA (1) ZA201000667B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2418427A (en) 2004-09-02 2006-03-29 Univ Cambridge Tech Ligands for G-protein coupled receptors
GB0512238D0 (en) * 2005-06-15 2005-07-27 Univ Cambridge Tech Anti-inflammatory agents
GB2452696B (en) * 2007-08-02 2009-09-23 Cambridge Entpr Ltd 3-(2',2'-dimethylpropanoylamino)-tetrahydropyridin-2-one and its use in pharmaceutical compositions
GB2455539B (en) * 2007-12-12 2012-01-18 Cambridge Entpr Ltd Anti-inflammatory compositions and combinations
EP2401611B1 (en) * 2009-02-27 2013-11-06 Cambridge Enterprise Limited Improved methods for identification
GB201009603D0 (en) 2010-06-08 2010-07-21 Cambridge Entpr Ltd Anti-inflammatory agent
US9340483B2 (en) * 2012-02-15 2016-05-17 Anida Pharma Inc. Methods of treating amyotrophic lateral sclerosis
IL268144B2 (en) * 2017-01-18 2024-05-01 Univ Barcelona Autonoma Targeted Segregation Assisted Lipid Mediators for Use in the Treatment of Neurodegenerative and/or Autoimmune Diseases

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA979446A (en) * 1971-06-28 1975-12-09 Yoshihiko Oka Nitrosourea derivatives
ZA893284B (en) 1988-05-04 1990-03-28 Igen Inc Peptide analogs and their use as haptens to elicit catalytic antibodies
JP3111321B2 (ja) * 1990-02-23 2000-11-20 武田薬品工業株式会社 縮合チアゾール化合物
IL97249A (en) 1990-02-23 1995-01-24 Takeda Chemical Industries Ltd Compounds of 7,6,5,4-tetrahydrothiazole] B-5,4 [pyridine and compounds of 5,6-dihydro-H4-pyrrolo] D-3,2 [thiazole, their manufacture, and pharmaceutical compositions including or
GB9108307D0 (en) 1991-04-18 1991-06-05 Univ Nottingham Autoinducer
IT1245870B (it) 1991-06-05 1994-10-25 Sigma Tau Ind Farmaceuti 3-acilammino-2-pirrolidinoni quali attivatori dei processi di appremdimento e della memoria e composizioni farmaceutiche comprendenti tali composti
EP0706393B1 (en) * 1993-07-02 1999-09-08 The University Of Nottingham Immunosuppressant and antiallergic compounds, e.g. n-(3-oxohexanoyl) homoserine lactone
US6077856A (en) 1995-11-13 2000-06-20 Smithkline Beecham Corporation Hemoregulatory compounds
GB9625865D0 (en) 1996-12-12 1997-01-29 Zeneca Ltd Peptides
JP3690052B2 (ja) * 1997-03-24 2005-08-31 Ｊｓｒ株式会社 オイルゲル化剤
PE107899A1 (es) 1997-09-09 1999-11-17 Glaxo Group Ltd Derivados de pirrolopirrolona como inhibidores de elastasa leucocitaria
US6989435B2 (en) 1997-09-11 2006-01-24 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
GB9725599D0 (en) * 1997-12-04 1998-02-04 Univ Nottingham Control of biofilm formation
AU1627799A (en) 1997-12-18 1999-07-05 Eli Lilly And Company Parallel solution phase synthesis of lactams
WO1999031507A1 (en) 1997-12-18 1999-06-24 Eli Lilly And Company Peptidomimetic template-based combinatorial libraries
US6395282B1 (en) 1998-04-16 2002-05-28 University Of Rochester Immunogenic conjugates of Gram-negative bacterial autoinducer molecules
GB9827499D0 (en) 1998-12-14 1999-02-10 Isis Innovation Lactams
JP4712975B2 (ja) 1999-01-12 2011-06-29 ケンブリッジ エンタープライズ リミティド 炎症反応を阻害又は増強するための組成物及び方法
FR2789390B3 (fr) * 1999-02-10 2001-03-09 Sanofi Sa Nouveaux derives de piperidine, procede pour leur obtention et compositions pharmaceutiques les contenant
GB9924195D0 (en) * 1999-10-13 1999-12-15 Univ Nottingham N-Acyl homoserine lactones for the treatment of cardiac tachyarrhythmias Ischaemic heart disease or congestive heart failure
HUP0203564A3 (en) * 1999-10-21 2004-07-28 Hoffmann La Roche Heteroalkylamino-substituted bicyclic nitrogen heterocycles as inhibitors of p38 protein kinease, process for their preparation and pharmaceutical compositions containing them
WO2001068655A2 (en) 2000-03-10 2001-09-20 Ariad Pharmaceuticals, Inc. Caprolactam derivatives and uses thereof
US6544981B2 (en) 2000-06-09 2003-04-08 Bristol-Myers Squibb Company Lactam inhibitors of factor Xa and method
EP1349558B1 (en) * 2000-12-12 2011-06-15 Angiolab, Inc. Composition comprising melissa leaf extract for anti-angiogenic and matrix metalloproteinase inhibitory activity
EP1361801B1 (en) * 2001-01-08 2007-06-06 Pathway Intermediates Limited Autoinducer compounds and their uses
WO2004022536A1 (en) 2002-09-04 2004-03-18 Glenmark Pharmaceuticals Limited New heterocyclic amide compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them
PT1691814E (pt) 2003-12-01 2012-10-16 Cambridge Entpr Ltd Agentes anti-inflamatórios
DE602005010824D1 (de) 2004-02-03 2008-12-18 Astrazeneca Ab Chinazolinderivate
GB2418425B (en) 2004-08-11 2008-09-03 Univ Cambridge Tech Anti-inflammatory agents
GB2418426A (en) 2004-08-18 2006-03-29 Univ Cambridge Tech Alpha-(acylamino)-bicyclolactam derivatives for treatment of inflammatory disorders
GB2418427A (en) * 2004-09-02 2006-03-29 Univ Cambridge Tech Ligands for G-protein coupled receptors
WO2006076442A2 (en) 2005-01-14 2006-07-20 Janssen Pharmaceutica N.V. Triazolopyrimidine derivatives
GB2423085C (en) 2005-02-11 2011-11-09 Cambridge Entpr Ltd Ligands for G-protein coupled receptors
TWI382855B (zh) * 2005-03-30 2013-01-21 Ajinomoto Kk 化妝用粉末
EP1896036B1 (en) * 2005-06-15 2013-01-23 Cambridge Enterprise Limited Anti-inflammatory agents
GB0512238D0 (en) * 2005-06-15 2005-07-27 Univ Cambridge Tech Anti-inflammatory agents
MY150958A (en) 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
GB2452696B (en) * 2007-08-02 2009-09-23 Cambridge Entpr Ltd 3-(2',2'-dimethylpropanoylamino)-tetrahydropyridin-2-one and its use in pharmaceutical compositions
US7662967B2 (en) 2007-08-02 2010-02-16 Cambridge Enterprise Limited Anti-inflammatory compounds and compositions

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US20150141460A1 (en) 2015-05-21
JP2010535186A (ja) 2010-11-18
EP2185151A1 (en) 2010-05-19
JP5680963B2 (ja) 2015-03-04
AU2008281570A1 (en) 2009-02-05
SI2185151T1 (sl) 2014-08-29
AU2008281570B2 (en) 2012-10-25
CA2695257A1 (en) 2009-02-05
CN101801377A (zh) 2010-08-11
CN102973562B (zh) 2014-12-24
ZA201000667B (en) 2010-09-29
ES2478243T3 (es) 2014-07-21
KR20100043258A (ko) 2010-04-28
DK2185151T3 (da) 2014-07-14
GB2452696A (en) 2009-03-18
CN101801377B (zh) 2013-01-02
AU2008281570C1 (en) 2013-06-06
NZ583503A (en) 2011-05-27
CY1115384T1 (el) 2017-01-04
CN102973562A (zh) 2013-03-20
US20100324089A1 (en) 2010-12-23
MX2010001243A (es) 2010-03-11
EP2185151B1 (en) 2014-04-09
RU2010103320A (ru) 2011-09-10
PT2185151E (pt) 2014-07-18
GB2452696B (en) 2009-09-23
HRP20140647T1 (hr) 2014-09-26
PL2185151T3 (pl) 2014-09-30
US8853200B2 (en) 2014-10-07
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GB0715068D0 (en) 2007-09-12
WO2009016390A1 (en) 2009-02-05

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