BR0210512A - Processo de decomposição papa o ácido (r)-(-)-2-hidroxi-2-(2-clorofenil) acético - Google Patents

Processo de decomposição papa o ácido (r)-(-)-2-hidroxi-2-(2-clorofenil) acético

Info

Publication number
BR0210512A
BR0210512A BR0210512-8A BR0210512A BR0210512A BR 0210512 A BR0210512 A BR 0210512A BR 0210512 A BR0210512 A BR 0210512A BR 0210512 A BR0210512 A BR 0210512A
Authority
BR
Brazil
Prior art keywords
hydroxy
acetic acid
chlorophenyl
decomposition process
acid decomposition
Prior art date
Application number
BR0210512-8A
Other languages
English (en)
Inventor
Jozsef Balint
Marianna Csatarine Nagy
Zsolt Dombrady
Elemer Fogassy
Antal Gajary
Charles Suba
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Publication of BR0210512A publication Critical patent/BR0210512A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/34—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton and at least one hydroxy group bound to another carbon atom of the carbon skeleton
    • C07C215/36—1-Aryl-2-amino-1,3-propane diols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/02—Preparation of carboxylic acids or their salts, halides or anhydrides from salts of carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

"PROCESSO DE DECOMPOSIçãO PARA O áCIDO (R)-(-)-2-HIDROXI-2-(2-CLOROFENIL) ACéTICO". O assunto da presente invenção e a preparação do ácido (R) - (-) -2-hidróxi-2- (2-clorofenil)acético de fórmula (I), por meio da decomposição do composto racêmico correspondente mediante o uso de compostos de fórmula geral (II).
BR0210512-8A 2001-06-21 2002-06-14 Processo de decomposição papa o ácido (r)-(-)-2-hidroxi-2-(2-clorofenil) acético BR0210512A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU0102567A HU230004B1 (en) 2001-06-21 2001-06-21 Resolution process for (r)-(-)-2-hydroxy-2-(2-chlorophenyl)-acetic acid
PCT/HU2002/000054 WO2003000636A1 (en) 2001-06-21 2002-06-14 Resolution process for (r)-(-)-2-hydroxy-2-(2-chlorophenyl) acetic acid

Publications (1)

Publication Number Publication Date
BR0210512A true BR0210512A (pt) 2004-06-22

Family

ID=89979445

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0210512-8A BR0210512A (pt) 2001-06-21 2002-06-14 Processo de decomposição papa o ácido (r)-(-)-2-hidroxi-2-(2-clorofenil) acético

Country Status (20)

Country Link
US (1) US7381835B2 (pt)
EP (1) EP1397335B1 (pt)
JP (1) JP4184260B2 (pt)
CN (1) CN1276907C (pt)
AT (1) ATE487688T1 (pt)
BR (1) BR0210512A (pt)
CA (1) CA2450490C (pt)
CY (1) CY1111606T1 (pt)
CZ (1) CZ305524B6 (pt)
DE (1) DE60238251D1 (pt)
DK (1) DK1397335T3 (pt)
ES (1) ES2354869T3 (pt)
HR (1) HRP20040057B1 (pt)
HU (2) HU230004B1 (pt)
MX (1) MXPA03011647A (pt)
PL (1) PL204820B1 (pt)
PT (1) PT1397335E (pt)
SI (1) SI1397335T1 (pt)
SK (1) SK287975B6 (pt)
WO (1) WO2003000636A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100678287B1 (ko) * 2005-06-23 2007-02-02 한미약품 주식회사 클로피도그렐의 제조방법 및 이에 사용되는 중간체
WO2007026860A1 (ja) * 2005-09-02 2007-03-08 Daiichi Fine Chemical Co., Ltd. 光学活性α－ヒドロキシカルボン酸の製造方法
CN102336653B (zh) * 2011-11-08 2014-04-30 广州市金匮贸易有限公司 光学纯手性邻氯扁桃酸的制备方法
CN102516002B (zh) * 2011-12-09 2014-04-02 中原工学院 一种光学纯α-羟基酸及其衍生物的制备工艺
EP3401929A1 (en) * 2017-05-09 2018-11-14 Borealis AG Cable insulation
CN109232220B (zh) * 2017-09-15 2021-09-10 上海健康医学院 一种3-羟基-3-苯基丙酸类化合物的化学拆分方法
CN110627808B (zh) * 2018-06-21 2022-04-01 江苏同禾药业有限公司 一种硫酸氢氯吡格雷拆分母液的回收处理工艺

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0665657B2 (ja) 1984-11-08 1994-08-24 日本化薬株式会社 光学活性マンデル酸の製法
EP0306585B1 (en) 1987-09-10 1992-07-22 International Business Machines Corporation Data transmission system with a digital alarm facility
DE3814887C1 (pt) 1988-05-02 1989-09-21 Medice Chem.-Pharm. Fabrik Puetter Gmbh & Co Kg, 5860 Iserlohn, De
US5380867A (en) 1992-12-02 1995-01-10 Hoechst Celanese Corporation Selective precipitation of α-aryl carboxylic acid salts
JPH10237013A (ja) 1996-12-28 1998-09-08 Fuji Yakuhin Kogyo Kk 光学活性２−ベンジルコハク酸の製造法
JP2002114737A (ja) * 2000-10-11 2002-04-16 Japan Hydrazine Co Inc 光学活性ｏ−クロロマンデル酸の製造法

Also Published As

Publication number Publication date
CA2450490C (en) 2010-04-06
CZ2004102A3 (cs) 2004-06-16
PT1397335E (pt) 2011-01-20
PL204820B1 (pl) 2010-02-26
CA2450490A1 (en) 2003-01-03
SK287975B6 (sk) 2012-08-06
MXPA03011647A (es) 2004-07-01
PL369004A1 (en) 2005-04-18
CN1276907C (zh) 2006-09-27
US20040242921A1 (en) 2004-12-02
SI1397335T1 (sl) 2011-03-31
JP4184260B2 (ja) 2008-11-19
HRP20040057B1 (en) 2012-02-29
HU230004B1 (en) 2015-04-28
DK1397335T3 (da) 2011-02-28
CY1111606T1 (el) 2015-10-07
EP1397335A1 (en) 2004-03-17
ES2354869T3 (es) 2011-03-18
CN1547566A (zh) 2004-11-17
EP1397335B1 (en) 2010-11-10
SK15342003A3 (sk) 2004-06-08
WO2003000636A1 (en) 2003-01-03
DE60238251D1 (de) 2010-12-23
HRP20040057A2 (en) 2004-08-31
ATE487688T1 (de) 2010-11-15
HUP0102567A2 (hu) 2005-03-29
JP2004530717A (ja) 2004-10-07
HUP0401404A3 (en) 2005-02-28
US7381835B2 (en) 2008-06-03
HUP0401404A2 (hu) 2004-11-29
HU229402B1 (hu) 2013-12-30
CZ305524B6 (cs) 2015-11-18

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Legal Events

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B25D Requested change of name of applicant approved

Owner name: SANOFI-AVENTIS (FR)

Free format text: ALTERADO DE: SANOFI-SYNTHELABO

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8 E 13 DA LPI

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.