BE854268A - Pyrrolidones, leur procede de preparation et leur application therapeutique - Google Patents

Pyrrolidones, leur procede de preparation et leur application therapeutique

Info

Publication number
BE854268A
BE854268A BE177278A BE177278A BE854268A BE 854268 A BE854268 A BE 854268A BE 177278 A BE177278 A BE 177278A BE 177278 A BE177278 A BE 177278A BE 854268 A BE854268 A BE 854268A
Authority
BE
Belgium
Prior art keywords
pyrrolidons
preparation process
therapeutic application
therapeutic
application
Prior art date
Application number
BE177278A
Other languages
English (en)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of BE854268A publication Critical patent/BE854268A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BE177278A 1976-05-04 1977-05-04 Pyrrolidones, leur procede de preparation et leur application therapeutique BE854268A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762619638 DE2619638A1 (de) 1976-05-04 1976-05-04 Pyrrolidone und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
BE854268A true BE854268A (fr) 1977-11-04

Family

ID=5977020

Family Applications (1)

Application Number Title Priority Date Filing Date
BE177278A BE854268A (fr) 1976-05-04 1977-05-04 Pyrrolidones, leur procede de preparation et leur application therapeutique

Country Status (9)

Country Link
JP (1) JPS52133975A (fr)
BE (1) BE854268A (fr)
DE (1) DE2619638A1 (fr)
DK (1) DK194377A (fr)
ES (1) ES458264A1 (fr)
FR (1) FR2372806A1 (fr)
GB (1) GB1583163A (fr)
IT (1) IT1086223B (fr)
NL (1) NL7704739A (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4320136A (en) 1980-08-11 1982-03-16 E. I. Du Pont De Nemours And Company 8-Aza-16,16-difluoroprostanoids
WO2003074483A1 (fr) 2002-03-05 2003-09-12 Ono Pharmaceutical Co., Ltd. Composes derives de 8 azaprostaglandine et medicaments contenant ceux-ci comme principe actif

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4321201A (en) 1980-09-22 1982-03-23 E. I. Du Pont De Nemours And Company Optically active tert-alkyl 7-(2-oxo-5-carbonyloxypyrrolidinyl) heptanoates
US5021568A (en) * 1988-04-22 1991-06-04 Shipov Alexandr G Lactam-1-acetic acid carbalkoxymethyl esters and method for preparing same
CZ20022048A3 (cs) 1999-12-22 2004-03-17 Pfizer Products Inc. Selektivní agonisty receptoru EP4 při léčení osteoporosy
AU2001290250A1 (en) * 2000-09-21 2002-04-02 Ono Pharmaceutical Co. Ltd. Ep4 receptor agonists containing 8-azaprostaglandin derivatives as the active ingredient
CZ20031257A3 (cs) * 2000-11-27 2004-04-14 Pfizer Products Inc. Selektivní agonisty receptoru EP4 při léčení osteoporosy
JP4211605B2 (ja) 2001-07-16 2009-01-21 小野薬品工業株式会社 プロスタノイドアゴニストとしての２ピロリドン誘導体
DE60208568T2 (de) * 2001-07-16 2006-10-05 F. Hoffmann-La Roche Ag Prostaglandinanaloga als ep4-rezeptoragonisten
PL367740A1 (en) 2001-07-23 2005-03-07 Ono Pharmaceutical Co, Ltd. Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient
JP4754820B2 (ja) * 2002-06-10 2011-08-24 メルク セローノ ソシエテ アノニム プロスタグランジン作動薬としてのγラクタムおよびその使用
PL378342A1 (pl) 2003-01-10 2006-03-20 F. Hoffmann-La Roche Ag Pochodne 2-piperydonu jako agoniści prostaglandyn
EP1586564B1 (fr) * 2003-01-21 2012-11-28 Ono Pharmaceutical Co., Ltd. Derives de 8-azaprostalangine et utilisations de ces derives en tant que medicaments
US7179820B2 (en) 2003-06-06 2007-02-20 Allergan, Inc. Piperidinyl prostaglandin E analogs
WO2006043655A1 (fr) 2004-10-22 2006-04-27 Ono Pharmaceutical Co., Ltd. Préparation thérapeutique pour inhalation
CN104640542B (zh) 2012-07-19 2017-09-22 开曼化学股份有限公司 用于ep4介导的骨相关疾病和病症的二氟内酰胺组合物
JP6368351B2 (ja) 2013-03-15 2018-08-01 ケイマン ケミカル カンパニー， インコーポレーテッド ジフルオロラクタムアナログを合成する方法
WO2014144610A1 (fr) * 2013-03-15 2014-09-18 Cayman Chemical Company, Inc. Composés lactames en tant qu'agonistes sélectifs du récepteur ep4 pour l'utilisation dans le traitement de maladies et d'états à médiation par ep4
WO2014144584A2 (fr) * 2013-03-15 2014-09-18 Cayman Chemical Company, Inc. Composés de lactame en tant qu'antagonistes sélectifs du récepteur ep4 pour une utilisation dans le traitement de maladies et d'états médiés par l'ep4
US10729810B2 (en) 2013-07-19 2020-08-04 Cayman Chemical Company, Inc Methods, systems, and compositions for promoting bone growth

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4320136A (en) 1980-08-11 1982-03-16 E. I. Du Pont De Nemours And Company 8-Aza-16,16-difluoroprostanoids
WO2003074483A1 (fr) 2002-03-05 2003-09-12 Ono Pharmaceutical Co., Ltd. Composes derives de 8 azaprostaglandine et medicaments contenant ceux-ci comme principe actif

Also Published As

Publication number Publication date
IT1086223B (it) 1985-05-28
ES458264A1 (es) 1978-07-16
DK194377A (da) 1977-11-05
JPS52133975A (en) 1977-11-09
DE2619638A1 (de) 1977-11-17
NL7704739A (nl) 1977-11-08
FR2372806B1 (fr) 1980-02-29
FR2372806A1 (fr) 1978-06-30
GB1583163A (en) 1981-01-21

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