AU8083094A - A diagnostic assay for alzheimer's disease: assessment of abeta abnormalities - Google Patents

A diagnostic assay for alzheimer's disease: assessment of abeta abnormalities

Info

Publication number
AU8083094A
AU8083094A AU80830/94A AU8083094A AU8083094A AU 8083094 A AU8083094 A AU 8083094A AU 80830/94 A AU80830/94 A AU 80830/94A AU 8083094 A AU8083094 A AU 8083094A AU 8083094 A AU8083094 A AU 8083094A
Authority
AU
Australia
Prior art keywords
abeta
abnormalities
alzheimer
assessment
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU80830/94A
Inventor
Ashley I Bush
Robert D Moir
Rudolph E Tanzi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Publication of AU8083094A publication Critical patent/AU8083094A/en
Abandoned legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4709Amyloid plaque core protein
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders
    • G01N2800/2821Alzheimer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurosurgery (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU80830/94A 1994-10-19 1994-10-19 A diagnostic assay for alzheimer's disease: assessment of abeta abnormalities Abandoned AU8083094A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1994/011895 WO1996012544A1 (en) 1994-10-19 1994-10-19 A DIAGNOSTIC ASSAY FOR ALZHEIMER'S DISEASE: ASSESSMENT OF Aβ ABNORMALITIES

Publications (1)

Publication Number Publication Date
AU8083094A true AU8083094A (en) 1996-05-15

Family

ID=22243151

Family Applications (1)

Application Number Title Priority Date Filing Date
AU80830/94A Abandoned AU8083094A (en) 1994-10-19 1994-10-19 A diagnostic assay for alzheimer's disease: assessment of abeta abnormalities

Country Status (3)

Country Link
AU (1) AU8083094A (en)
CA (1) CA2203142C (en)
WO (1) WO1996012544A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7045531B1 (en) 1997-03-11 2006-05-16 The General Hospital Corporation Composition comprising a metal chelator and a method of treating amyloidosis by administering the metal chelator
US7078191B1 (en) 1997-08-01 2006-07-18 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Composition and method for the detection of diseases associated with amyloid-like fibril or protein aggregate formation
EP1005654B1 (en) 1997-08-01 2006-04-12 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Novel method of detecting amyloid-like fibrils or protein aggregates
ATE323288T1 (en) * 1997-08-01 2006-04-15 METHOD FOR DETERMINING AMYLOID-LIKE FIBRILES OR PROTEIN AGGREGATES
US6638711B1 (en) 1999-04-29 2003-10-28 The General Hospital Corporation Methods for identifying an agent that inhibits oxygen-dependent hydrogen peroxide formation activity but does not inhibit superoxide-dependent hydrogen peroxide formation
PT2579042E (en) 2011-10-04 2014-09-09 Affiris Ag Method for detecting aãy-specific antibodies in a biological sample

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4666829A (en) * 1985-05-15 1987-05-19 University Of California Polypeptide marker for Alzheimer's disease and its use for diagnosis
US5231000A (en) * 1987-10-08 1993-07-27 The Mclean Hospital Antibodies to A4 amyloid peptide
US5262332A (en) * 1989-04-05 1993-11-16 Brigham And Women's Hospital Diagnostic method for Alzheimer's disease: examination of non-neural tissue
EP0683234B2 (en) * 1993-01-25 2007-06-06 Takeda Chemical Industries, Ltd. Antibody against beta-amyloid or their derivative and use thereof

Also Published As

Publication number Publication date
WO1996012544A1 (en) 1996-05-02
CA2203142C (en) 2006-01-31
CA2203142A1 (en) 1996-05-02

Similar Documents

Publication Publication Date Title
AU3891499A (en) Diagnostic tests for alzheimer's disease
AU5508798A (en) Diagnostic and therapeutic reagents for alzheimer's disease
AU2610901A (en) Predictive diagnostic for alzheimer's disease
EP0773797A4 (en) A method of diagnosing alzheimer's disease
AU2414092A (en) Diagnostic method for alzheimer's disease
AU1407399A (en) Treatment for alzheimer's disease
EP1011415A4 (en) Non-invasive method for diagnosing alzheimer's disease in a patient
AU672379B2 (en) Diagnostic assay for Alzheimer's Disease based on the proteolysis of Alzheimer's precursor protein
AU1837495A (en) Computer assisted methods for diagnosing diseases
AU5292290A (en) Diagnostic method for alzheimer's disease: examination of non-neural tissue
AU7708498A (en) Nematode model for alzheimer's disease
AU7556994A (en) Methods for the diagnosis of alzheimer's disease
AU8388098A (en) Assays for diagnosis of thrombophilic disease
AU1441988A (en) Amyloidosis and alzheimer's disease diagnostic assay and reagents therefor
AU5857296A (en) Use of leukotriene antagonists for alzheimer's disease
HUP0003684A3 (en) Diagnostic test for alzheimer's disease
AU2001236592A1 (en) Methods for diagnosis of alzheimer's disease
AUPN649395A0 (en) A method for diagnosing alzheimer's disease
AU4636993A (en) Diagnosing alzheimer's disease and schizophrenia
IL118925A0 (en) Substituted cinnamic acid guanidides a process for their preparation their use as medicaments or diagnostic agents and medicaments comprising them
AU3068899A (en) Diagnostic assay for late-onset alzheimer's disease
AU8083094A (en) A diagnostic assay for alzheimer's disease: assessment of abeta abnormalities
AU5053296A (en) Pharmaceutical agents for the treatment of Alzheimer's disease
IL140222A0 (en) A method and diagnostic kit for detecting alzheimer's disease
AU1405899A (en) Treatment for alzheimer's disease