US5989920A
(en)
|
1994-12-02 |
1999-11-23 |
Synaptic Pharmaceutical Corporation |
Methods of modifying feeding behavior compounds useful in such methods and DNA encoding a hypothalmic atypical neuropeptide Y/peptide YY receptor Y5
|
US5602024A
(en)
|
1994-12-02 |
1997-02-11 |
Synaptic Pharmaceutical Corporation |
DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5) and uses thereof
|
AUPN646795A0
(en)
|
1995-11-09 |
1995-11-30 |
Garvan Institute Of Medical Research |
Neuropeptide Y-Y5 receptor
|
EP1007073A4
(en)
*
|
1996-06-04 |
2002-03-27 |
Synaptic Pharma Corp |
Methods of modifying feeding behavior, compounds useful in such methods, and dna encoding a hypothalamic atypical neuropeptide y/peptide yy receptor (y5)
|
US6713265B1
(en)
|
1997-06-04 |
2004-03-30 |
Synaptic Pharmaceutical Corporation |
Methods of modifying feeding behavior, compounds useful in such methods, and DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5)
|
AU1262199A
(en)
*
|
1997-11-28 |
1999-06-16 |
Banyu Pharmaceutical Co., Ltd. |
Antihyperlipemic agents
|
US6187777B1
(en)
|
1998-02-06 |
2001-02-13 |
Amgen Inc. |
Compounds and methods which modulate feeding behavior and related diseases
|
US6221875B1
(en)
|
1998-04-02 |
2001-04-24 |
Neurogen Corporation |
Substituted 9H-pyridino [2,3-B]indole and 9H-pyrimidino [4,5-B]indole derivatives: selective neuropeptide Y receptor ligands
|
US6770658B2
(en)
|
1998-09-09 |
2004-08-03 |
Inflazyme Pharmaceuticals Ltd. |
Substituted γ-phenyl-Δ-lactams and uses related thereto
|
AU763886B2
(en)
*
|
1998-10-07 |
2003-07-31 |
Ortho-Mcneil Pharmaceutical, Inc. |
N-aralkylaminotetralins as ligands for the neuropeptide Y Y5 receptor
|
US6191160B1
(en)
|
1998-11-10 |
2001-02-20 |
Merck & Co., Inc. |
Spiro-indolines as Y5 receptor antagonists
|
US6407120B1
(en)
|
1999-02-18 |
2002-06-18 |
Pfizer Inc. |
Neuropeptide Y antagonists
|
AU3840000A
(en)
|
1999-04-20 |
2000-11-02 |
Meiji Seika Kaisha Ltd. |
Tricyclic compounds
|
WO2001068615A1
(en)
*
|
2000-03-13 |
2001-09-20 |
Chemrx Advanced Technologies, Inc. |
Quinazoline synthesis
|
KR20030016396A
(en)
|
2000-07-13 |
2003-02-26 |
일라이 릴리 앤드 캄파니 |
Beta3 adrenergic agonists
|
PE20030008A1
(en)
|
2001-06-19 |
2003-01-22 |
Bristol Myers Squibb Co |
DUAL INHIBITORS OF PDE 7 AND PDE 4
|
WO2003028641A2
(en)
*
|
2001-10-01 |
2003-04-10 |
Taisho Pharmaceutical Co., Ltd. |
Mch receptor antagonists
|
CA2403307A1
(en)
|
2001-10-23 |
2003-04-23 |
Neurogen Corporation |
Substituted 2-cyclohexyl-4-phenyl-1h-imidazole derivatives
|
WO2003055866A1
(en)
*
|
2001-12-21 |
2003-07-10 |
Bayer Pharmaceuticals Corporation |
Quinazoline and quinoline derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents
|
US7105526B2
(en)
|
2002-06-28 |
2006-09-12 |
Banyu Pharmaceuticals Co., Ltd. |
Benzimidazole derivatives
|
US7491827B2
(en)
|
2002-12-23 |
2009-02-17 |
Millennium Pharmaceuticals, Inc. |
Aryl sulfonamides useful as inhibitors of chemokine receptor activity
|
WO2004058709A1
(en)
|
2002-12-23 |
2004-07-15 |
Millennium Pharmaceuticals, Inc. |
Ccr8 inhibitors
|
TW200510311A
(en)
|
2002-12-23 |
2005-03-16 |
Millennium Pharm Inc |
CCr8 inhibitors
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
US20070010671A1
(en)
*
|
2003-03-31 |
2007-01-11 |
Yoshinori Sekiguchi |
Novel quinazoline derivatives and methods of treatment related to the use thereof
|
JP2004315511A
(en)
*
|
2003-03-31 |
2004-11-11 |
Taisho Pharmaceut Co Ltd |
Mch receptor antagonist
|
ATE462432T1
(en)
|
2003-05-05 |
2010-04-15 |
Probiodrug Ag |
GLUTAMINYL CYCLASE INHIBITORS
|
US20060148893A1
(en)
*
|
2003-06-10 |
2006-07-06 |
Blanc Jean-Baptiste E |
Chemical compounds
|
US8309562B2
(en)
|
2003-07-03 |
2012-11-13 |
Myrexis, Inc. |
Compounds and therapeutical use thereof
|
JP4765627B2
(en)
|
2003-09-22 |
2011-09-07 |
Msd株式会社 |
Novel piperidine derivatives
|
US20070135485A1
(en)
|
2003-10-22 |
2007-06-14 |
Gillig James R |
Novel mch receptor antagonists
|
WO2005049027A2
(en)
|
2003-11-03 |
2005-06-02 |
Probiodrug Ag |
Combinations useful for the treatment of neuronal disorders
|
WO2005075436A2
(en)
|
2004-02-05 |
2005-08-18 |
Probiodrug Ag |
Novel inhibitors of glutaminyl cyclase
|
FR2866887A1
(en)
*
|
2004-02-27 |
2005-09-02 |
Oreal |
N-HETEROARYL SECONDARY PARA-PHENYLENEDIAMINE, TINCTORIAL COMPOSITION COMPRISING SUCH A PARA-PHENYLENEDIAMINE, PROCESS USING THE SAME AND USE THEREOF
|
US7329288B2
(en)
|
2004-02-27 |
2008-02-12 |
L'oreal S.A. |
N-heteroaryl secondary para-phenylenediamine, a dye composition comprising such a para-phenylenediamine, a process for preparing this composition and use thereof
|
EP1734963A4
(en)
|
2004-04-02 |
2008-06-18 |
Merck & Co Inc |
Method of treating men with metabolic and anthropometric disorders
|
EP2127676A3
(en)
|
2004-11-01 |
2013-09-04 |
Amylin Pharmaceuticals, LLC |
Treatment of obesity and related disorders
|
US8394765B2
(en)
|
2004-11-01 |
2013-03-12 |
Amylin Pharmaceuticals Llc |
Methods of treating obesity with two different anti-obesity agents
|
EP1833482A4
(en)
|
2005-01-03 |
2011-02-16 |
Myriad Genetics Inc |
Compounds and therapeutical use thereof
|
US8258145B2
(en)
|
2005-01-03 |
2012-09-04 |
Myrexis, Inc. |
Method of treating brain cancer
|
WO2006105056A2
(en)
*
|
2005-03-28 |
2006-10-05 |
Fmc Corporation |
Insecticidal 2,4-diaminoquinazolines and related derivatives
|
US7737155B2
(en)
|
2005-05-17 |
2010-06-15 |
Schering Corporation |
Nitrogen-containing heterocyclic compounds and methods of use thereof
|
EP1892241B1
(en)
|
2005-05-30 |
2016-03-30 |
Msd K.K. |
Novel piperidine derivative
|
EP1916239A4
(en)
|
2005-08-10 |
2009-10-21 |
Banyu Pharma Co Ltd |
Pyridone compound
|
AU2006279680B2
(en)
|
2005-08-11 |
2012-12-06 |
Amylin Pharmaceuticals, Llc |
Hybrid polypeptides with selectable properties
|
EP2330125A3
(en)
|
2005-08-11 |
2012-12-12 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides with selectable properties
|
JPWO2007024004A1
(en)
|
2005-08-24 |
2009-03-05 |
萬有製薬株式会社 |
Phenylpyridone derivatives
|
US20090264426A1
(en)
|
2005-09-07 |
2009-10-22 |
Shunji Sakuraba |
Bicyclic aromatic substituted pyridone derivative
|
CN101277960A
(en)
|
2005-09-29 |
2008-10-01 |
默克公司 |
Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
|
CA2625416A1
(en)
|
2005-10-21 |
2007-04-26 |
Novartis Ag |
Combination of a renin-inhibitor and an anti-dyslipidemic agent and/or an antiobesity agent
|
AU2006307046A1
(en)
|
2005-10-27 |
2007-05-03 |
Msd K.K. |
Novel benzoxathiin derivative
|
RU2428423C2
(en)
|
2005-11-10 |
2011-09-10 |
Баниу Фармасьютикал Ко., Лтд. |
Aza-substituted spiro-derivatives
|
EP1960372B1
(en)
|
2005-12-15 |
2015-12-09 |
Rigel Pharmaceuticals, Inc. |
Kinase inhibitors and their uses
|
KR101462393B1
(en)
|
2006-04-20 |
2014-11-18 |
얀센 파마슈티카 엔.브이. |
Inhibitors of c-fms kinase
|
EP2083831B1
(en)
|
2006-09-22 |
2013-12-25 |
Merck Sharp & Dohme Corp. |
Method of treatment using fatty acid synthesis inhibitors
|
AU2007301126A1
(en)
|
2006-09-28 |
2008-04-03 |
Banyu Pharmaceutical Co., Ltd. |
Diaryl ketimine derivative
|
EP2089383B1
(en)
|
2006-11-09 |
2015-09-16 |
Probiodrug AG |
3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases
|
JP5523107B2
(en)
|
2006-11-30 |
2014-06-18 |
プロビオドルグ エージー |
Novel inhibitors of glutaminyl cyclase
|
EP2117540A1
(en)
|
2007-03-01 |
2009-11-18 |
Probiodrug AG |
New use of glutaminyl cyclase inhibitors
|
WO2008120653A1
(en)
|
2007-04-02 |
2008-10-09 |
Banyu Pharmaceutical Co., Ltd. |
Indoledione derivative
|
US9656991B2
(en)
|
2007-04-18 |
2017-05-23 |
Probiodrug Ag |
Inhibitors of glutaminyl cyclase
|
ES2559319T3
(en)
|
2007-06-04 |
2016-02-11 |
Synergy Pharmaceuticals Inc. |
Guanylate cliclas agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
TWI389893B
(en)
*
|
2007-07-06 |
2013-03-21 |
Astellas Pharma Inc |
Di (arylamino) ary1 compound
|
EP2264026A4
(en)
|
2008-03-06 |
2012-03-28 |
Msd Kk |
Alkylaminopyridine derivative
|
CA2717384A1
(en)
|
2008-03-28 |
2009-10-01 |
Banyu Pharmaceutical Co., Ltd. |
Diarylmethylamide derivative having melanin-concentrating hormone receptor antagonism
|
KR101860057B1
(en)
|
2008-05-21 |
2018-05-21 |
어리어드 파마슈티칼스, 인코포레이티드 |
Phosphorous derivatives as kinase inhibitors
|
US9273077B2
(en)
|
2008-05-21 |
2016-03-01 |
Ariad Pharmaceuticals, Inc. |
Phosphorus derivatives as kinase inhibitors
|
JP2011522828A
(en)
|
2008-06-04 |
2011-08-04 |
シナジー ファーマシューティカルズ インコーポレイテッド |
Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer, and other disorders
|
US20110071129A1
(en)
|
2008-06-19 |
2011-03-24 |
Makoto Ando |
Spirodiamine-diaryl ketoxime derivative
|
WO2010009319A2
(en)
|
2008-07-16 |
2010-01-21 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
|
CA2731358A1
(en)
|
2008-07-30 |
2010-02-04 |
Banyu Pharmaceutical Co., Ltd. |
5/5-or 5/6-membered condensed ring cycloalkylamine derivative
|
CA2741125A1
(en)
|
2008-10-22 |
2010-04-29 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
AU2009308980B2
(en)
|
2008-10-30 |
2013-02-28 |
Merck Sharp & Dohme Corp. |
Isonicotinamide orexin receptor antagonists
|
JP5557845B2
(en)
|
2008-10-31 |
2014-07-23 |
メルク・シャープ・アンド・ドーム・コーポレーション |
Novel cyclic benzimidazole derivatives useful as antidiabetic agents
|
WO2010075068A1
(en)
|
2008-12-16 |
2010-07-01 |
Schering Corporation |
Pyridopyrimidine derivatives and methods of use thereof
|
US20110243940A1
(en)
|
2008-12-16 |
2011-10-06 |
Schering Corporation |
Bicyclic pyranone derivatives and methods of use thereof
|
CN101463014B
(en)
*
|
2008-12-26 |
2013-07-10 |
复旦大学 |
Diaryl benzo pyridine derivative, and its pharmaceutical composition and use thereof
|
AU2010294214B2
(en)
|
2009-09-11 |
2015-05-07 |
Vivoryon Therapeutics N.V. |
Heterocylcic derivatives as inhibitors of glutaminyl cyclase
|
AU2011218830B2
(en)
|
2010-02-25 |
2014-07-24 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
JP6026284B2
(en)
|
2010-03-03 |
2016-11-16 |
プロビオドルグ エージー |
Inhibitors of glutaminyl cyclase
|
KR101790806B1
(en)
|
2010-03-10 |
2017-11-20 |
프로비오드룩 아게 |
Heterocyclic inhibitors of glutaminyl cyclase (qc, ec 2.3.2.5)
|
WO2011131748A2
(en)
|
2010-04-21 |
2011-10-27 |
Probiodrug Ag |
Novel inhibitors
|
EP2563123B1
(en)
|
2010-04-30 |
2018-04-25 |
Merck Sharp & Dohme Corp. |
Novel beta 3 adrenergic receptor agonists
|
CN102250075B
(en)
*
|
2010-05-21 |
2016-09-21 |
中国医学科学院药物研究所 |
2,4-disubstituted quinazoline compounds and preparation method thereof and pharmaceutical composition and purposes
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
EA201690035A1
(en)
|
2011-02-25 |
2016-05-31 |
Мерк Шарп Энд Домэ Корп. |
NEW CYCLIC DERIVATIVES OF AZABENZIMIDAZOLE, USED AS ANTI-DIABETIC AGENTS
|
DK2686313T3
(en)
|
2011-03-16 |
2016-05-02 |
Probiodrug Ag |
Benzimidazole derivatives as inhibitors of glutaminyl cyclase
|
MX360404B
(en)
|
2011-05-04 |
2018-10-31 |
Ariad Pharma Inc |
Compounds for inhibiting cell proliferation in egfr-driven cancers.
|
AR088352A1
(en)
|
2011-10-19 |
2014-05-28 |
Merck Sharp & Dohme |
ANTAGONISTS OF THE RECEIVER OF 2-PIRIDILOXI-4-NITRILE OREXINE
|
AU2013204563B2
(en)
|
2012-05-05 |
2016-05-19 |
Takeda Pharmaceutical Company Limited |
Compounds for inhibiting cell proliferation in EGFR-driven cancers
|
BR112014031068A2
(en)
|
2012-06-12 |
2017-06-27 |
Abbvie Inc |
pyridinone and pyridazinone derivatives
|
AU2013296470B2
(en)
|
2012-08-02 |
2016-03-17 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
CN104994848A
(en)
|
2013-02-22 |
2015-10-21 |
默沙东公司 |
Antidiabetic bicyclic compounds
|
EP2970119B1
(en)
|
2013-03-14 |
2021-11-03 |
Merck Sharp & Dohme Corp. |
Novel indole derivatives useful as anti-diabetic agents
|
US9708367B2
(en)
|
2013-03-15 |
2017-07-18 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase and their uses
|
EP2968439A2
(en)
|
2013-03-15 |
2016-01-20 |
Synergy Pharmaceuticals Inc. |
Compositions useful for the treatment of gastrointestinal disorders
|
US9611283B1
(en)
|
2013-04-10 |
2017-04-04 |
Ariad Pharmaceuticals, Inc. |
Methods for inhibiting cell proliferation in ALK-driven cancers
|
PT3004138T
(en)
|
2013-06-05 |
2024-06-18 |
Bausch Health Ireland Ltd |
Ultra-pure agonists of guanylate cyclase c, method of making and using same
|
WO2015051496A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
RU2021109549A
(en)
|
2014-08-29 |
2021-05-13 |
Тес Фарма С.Р.Л. |
Α-AMINO-β-CARBOXYMUCONATE INHIBITORS of ε-SEMIALDEHYDE-DECARBOXYLASE
|
CN105713000A
(en)
*
|
2014-12-02 |
2016-06-29 |
重庆宁牧生态农业有限公司 |
Compound taken as anti-obesity agent
|
CN105712997A
(en)
*
|
2014-12-02 |
2016-06-29 |
重庆宁牧生态农业有限公司 |
Compound taken as anti-obesity agent
|
CN105646450A
(en)
*
|
2014-12-02 |
2016-06-08 |
重庆宁牧生态农业有限公司 |
Compound used as anti-obesity agent
|
WO2018069532A1
(en)
|
2016-10-14 |
2018-04-19 |
Tes Pharma S.R.L. |
Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
|
US11072602B2
(en)
|
2016-12-06 |
2021-07-27 |
Merck Sharp & Dohme Corp. |
Antidiabetic heterocyclic compounds
|
US10968232B2
(en)
|
2016-12-20 |
2021-04-06 |
Merck Sharp & Dohme Corp. |
Antidiabetic spirochroman compounds
|
EP3594203B1
(en)
*
|
2017-03-08 |
2021-08-04 |
Takeda Pharmaceutical Company Limited |
Substituted pyrrolidine compound and use thereof
|
DK3461819T3
(en)
|
2017-09-29 |
2020-08-10 |
Probiodrug Ag |
GLUTAMINYL CYCLASE INHIBITORS
|
CN113302189A
(en)
|
2018-11-20 |
2021-08-24 |
Tes制药有限责任公司 |
Inhibitors of alpha-amino-beta-carboxyadipimic acid semialdehyde decarboxylating enzyme
|
EP3886854A4
(en)
|
2018-11-30 |
2022-07-06 |
Nuvation Bio Inc. |
Pyrrole and pyrazole compounds and methods of use thereof
|
WO2020167706A1
(en)
|
2019-02-13 |
2020-08-20 |
Merck Sharp & Dohme Corp. |
5-alkyl pyrrolidine orexin receptor agonists
|
US20230018413A1
(en)
|
2019-08-08 |
2023-01-19 |
Merck Sharp & Dohme Corp. |
Heteroaryl pyrrolidine and piperidine orexin receptor agonists
|
WO2021155426A1
(en)
*
|
2020-02-04 |
2021-08-12 |
TroBio Therapeutics Pty Ltd |
Quinazoline compounds and the use thereof in the treatment of cancer
|
JP7443625B2
(en)
|
2020-08-18 |
2024-03-05 |
メルク・シャープ・アンド・ドーム・エルエルシー |
Bicycloheptane pyrrolidine orexin receptor agonist
|
JP2024536926A
(en)
*
|
2021-09-07 |
2024-10-08 |
ギズモ セラピューティクス インコーポレイテッド |
Compounds and pharmaceutical compositions comprising inhibitors of amyloid peptide interaction with glycosaminoglycans, methods of treatment, and uses thereof - Patents.com
|
WO2024131938A1
(en)
*
|
2022-12-23 |
2024-06-27 |
赛诺哈勃药业(成都)有限公司 |
Quinazoline compound and use thereof
|