AU3761393A - Indole derivatives with antiviral activity - Google Patents

Indole derivatives with antiviral activity

Info

Publication number
AU3761393A
AU3761393A AU37613/93A AU3761393A AU3761393A AU 3761393 A AU3761393 A AU 3761393A AU 37613/93 A AU37613/93 A AU 37613/93A AU 3761393 A AU3761393 A AU 3761393A AU 3761393 A AU3761393 A AU 3761393A
Authority
AU
Australia
Prior art keywords
antiviral activity
indole derivatives
indole
derivatives
antiviral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU37613/93A
Inventor
George Stuart Cockerill
Edward Littler
Martin John Slater
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929206056A external-priority patent/GB9206056D0/en
Priority claimed from GB929206809A external-priority patent/GB9206809D0/en
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of AU3761393A publication Critical patent/AU3761393A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU37613/93A 1992-03-20 1993-03-19 Indole derivatives with antiviral activity Abandoned AU3761393A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9206056 1992-03-20
GB929206056A GB9206056D0 (en) 1992-03-20 1992-03-20 Indole derivatives
GB929206809A GB9206809D0 (en) 1992-03-27 1992-03-27 Indole derivatives
GB9206809 1992-03-27

Publications (1)

Publication Number Publication Date
AU3761393A true AU3761393A (en) 1993-10-21

Family

ID=26300558

Family Applications (1)

Application Number Title Priority Date Filing Date
AU37613/93A Abandoned AU3761393A (en) 1992-03-20 1993-03-19 Indole derivatives with antiviral activity

Country Status (4)

Country Link
EP (1) EP0630241A1 (en)
JP (1) JPH07504673A (en)
AU (1) AU3761393A (en)
WO (1) WO1993018765A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1449529B1 (en) * 1993-12-23 2010-01-27 Eli Lilly And Company Protein Kinase C Inhibitors
EP0675125A1 (en) * 1994-03-18 1995-10-04 Kyowa Hakko Kogyo Co., Ltd. A therapeutic agent for thrombocytopenia and indolocarbazole derivatives
US5491242A (en) * 1994-06-22 1996-02-13 Eli Lilly And Company Protein kinase C inhibitors
PE91498A1 (en) * 1996-07-29 1998-12-22 Hoffmann La Roche SUBSTITUTED PYRROLES
PE91698A1 (en) * 1996-07-29 1998-12-24 Hoffmann La Roche SUBSTITUTED PYRROLES
PE91598A1 (en) 1996-07-29 1998-12-24 Hoffmann La Roche SUBSTITUTED PYRROLES
SE9603283D0 (en) * 1996-09-10 1996-09-10 Astra Ab New compounds
TW472045B (en) 1996-09-25 2002-01-11 Astra Ab Protein kinase C inhibitor compounds, method for their preparation, pharmaceutical composition thereof and intermediate used for their preparation
AR017200A1 (en) 1997-12-23 2001-08-22 Astrazeneca Ab INHIBITING COMPOUNDS OF PROTEIN CINASE C, PHARMACEUTICALLY ACCEPTABLE SALTS OF THE SAME, PHARMACEUTICAL FORMULATIONS THAT UNDERSTAND THEM, USE THE SAME AND PROCESS FOR THE SYNTHESIS OF SUCH COMPOUNDS
AU2548699A (en) * 1998-02-23 1999-09-06 Rei Asakai Cell death inhibitors
SE9800835D0 (en) 1998-03-13 1998-03-13 Astra Ab New Compounds
US6492406B1 (en) 1999-05-21 2002-12-10 Astrazeneca Ab Pharmaceutically active compounds
US6346625B1 (en) 1999-06-23 2002-02-12 Astrazeneca Ab Protein kinase inhibitors
US6281356B1 (en) 1999-12-22 2001-08-28 Hoffmann-La Roche Inc. Substituted pyrroles
TWI335221B (en) 2001-09-27 2011-01-01 Alcon Inc Inhibtors of glycogen synthase kinase-3 (gsk-3) for treating glaucoma
WO2003037894A1 (en) * 2001-11-02 2003-05-08 Glaxo Group Limited 4-(5-membered)-heteroaryl acyl pyrrolidine derivatives as hcv inhibitors
US7259163B2 (en) 2001-11-02 2007-08-21 Glaxo Group Limited 4-(6-membered)-heteroaryl acyl pyrrolidine derivatives as HCV inhibitors
GB0303319D0 (en) 2003-02-13 2003-03-19 Novartis Ag Organic compounds
US7781478B2 (en) 2004-07-14 2010-08-24 Ptc Therapeutics, Inc. Methods for treating hepatitis C
CN101133055B (en) 2005-02-09 2011-05-25 艾科优公司 MELEIMId derivative for treating cancer, compositions and methods
WO2008117935A1 (en) * 2007-03-28 2008-10-02 Industry-Academic Cooperation Foundation, Yonsei University Nk cell activating molecules, nk cells and pharmaceutical compositons comprising the same
EP2173748B1 (en) 2007-06-22 2011-08-31 ArQule, Inc. Indolyl pyrrolidines for the treatment of cancer
MX2009013815A (en) 2007-06-22 2010-03-01 Arqule Inc Quinazolinone compounds and methods of use thereof.
JP5425060B2 (en) 2007-06-22 2014-02-26 アークル インコーポレイテッド Pyrrolidinone, pyrrolidine-2,5-dione, pyrrolidine and thiosuccinimide derivatives, compositions and methods for the treatment of cancer
EP3169337A1 (en) 2014-07-17 2017-05-24 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for treating neuromuscular junction-related diseases
WO2016207366A1 (en) 2015-06-26 2016-12-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of viral infections
CN110218206B (en) * 2016-06-01 2022-03-04 中国海洋大学 Bisindolylmaleimide derivative and preparation method and application thereof
PL3860998T3 (en) 2018-10-05 2024-06-17 Annapurna Bio Inc. Compounds and compositions for treating conditions associated with apj receptor activity
WO2021126804A1 (en) * 2019-12-18 2021-06-24 Merck Sharp & Dohme Corp. Indazole derivatives and methods of use thereof for the treatment of herpes viruses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ280738B6 (en) * 1988-02-10 1996-04-17 F. Hoffmann - La Roche And Co., Aktiengesellschaft Substituted pyrroles, their use for preparing medicaments and medicaments based thereon
MC2096A1 (en) * 1989-02-23 1991-02-15 Hoffmann La Roche SUBSTITUTED PYRROLES
IL94274A0 (en) * 1989-05-05 1991-03-10 Goedecke Ag Maleinimide derivatives,process for the preparation thereof and pharmaceutical compositions containing the same
DE3914764A1 (en) * 1989-05-05 1990-11-08 Goedecke Ag New bis(1H-indol-3-yl) maleinimide derivs. - are inhibitors of protein kinase C for treatment of cardiovascular, CNS and immune system disorders
CA2046801C (en) * 1990-08-07 2002-02-26 Peter D. Davis Substituted pyrroles

Also Published As

Publication number Publication date
EP0630241A1 (en) 1994-12-28
JPH07504673A (en) 1995-05-25
WO1993018765A1 (en) 1993-09-30

Similar Documents

Publication Publication Date Title
AU3761393A (en) Indole derivatives with antiviral activity
AU3692393A (en) Indole derivatives
AU4156293A (en) Thiazolylvinylphenyl derivatives
AU3349893A (en) Indole derivatives
AU3296893A (en) Benzimidazolyl derivatives
AU3978689A (en) Nucleoside derivatives
AU4271193A (en) Indole derivative
ZA932440B (en) Indole derivatives
AU7621294A (en) Antiviral indole derivatives
AU4123793A (en) Benzimidazole derivatives
AU3388893A (en) Pyrimidine derivatives
AU1604492A (en) Indole derivatives
AU5184293A (en) Phthalazinone derivatives
AU3406793A (en) 2-oxoquinoline derivatives
AU4829793A (en) Quinazoline derivatives
AU622725B2 (en) Tetralin derivatives
AU3195993A (en) Heterocyclic derivatives
AU3526989A (en) 2-amino-pyrimidine derivatives
AU3697893A (en) Propenoyl-imidazole derivatives
AU3262493A (en) Amino acid derivatives with anticholecystokinin activity
AU3607189A (en) Pyrimidine derivatives
AU4620693A (en) Substituted acetamide derivatives
GB9204024D0 (en) Indole derivatives
AU2991295A (en) Sustance with antiviral activity
HU9302748D0 (en) 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[c,d]indole derivatives