ATE412400T1 - Öl-in-wasser-emulsion mit niedriger konzentration des kationischen mittels und positivem zetapotential - Google Patents
Öl-in-wasser-emulsion mit niedriger konzentration des kationischen mittels und positivem zetapotentialInfo
- Publication number
- ATE412400T1 ATE412400T1 AT04292645T AT04292645T ATE412400T1 AT E412400 T1 ATE412400 T1 AT E412400T1 AT 04292645 T AT04292645 T AT 04292645T AT 04292645 T AT04292645 T AT 04292645T AT E412400 T1 ATE412400 T1 AT E412400T1
- Authority
- AT
- Austria
- Prior art keywords
- oil
- water emulsion
- cationic agent
- zeta potential
- agent concentration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Transplantation (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Colloid Chemistry (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04292645A EP1655021B1 (de) | 2004-11-09 | 2004-11-09 | Öl-in-Wasser-Emulsion mit niedriger Konzentration des kationischen Mittels und positivem Zetapotential |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE412400T1 true ATE412400T1 (de) | 2008-11-15 |
Family
ID=34931510
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04292645T ATE412400T1 (de) | 2004-11-09 | 2004-11-09 | Öl-in-wasser-emulsion mit niedriger konzentration des kationischen mittels und positivem zetapotential |
AT08102553T ATE498392T1 (de) | 2004-11-09 | 2005-10-10 | Ophthalmische emulsionen mit einem immunsuppressiven mittel |
AT05795930T ATE418964T1 (de) | 2004-11-09 | 2005-10-10 | Ophthalmische öl-in-wasser-emulsion mit stabilem positivem zeta-potential |
AT05800012T ATE415942T1 (de) | 2004-11-09 | 2005-10-10 | Prostaglandine enthaltende ophthalmische emulsionen |
AT05802097T ATE412401T1 (de) | 2004-11-09 | 2005-10-10 | Ophthalmische emulsion mit einem immunosuppressiven mittel |
Family Applications After (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT08102553T ATE498392T1 (de) | 2004-11-09 | 2005-10-10 | Ophthalmische emulsionen mit einem immunsuppressiven mittel |
AT05795930T ATE418964T1 (de) | 2004-11-09 | 2005-10-10 | Ophthalmische öl-in-wasser-emulsion mit stabilem positivem zeta-potential |
AT05800012T ATE415942T1 (de) | 2004-11-09 | 2005-10-10 | Prostaglandine enthaltende ophthalmische emulsionen |
AT05802097T ATE412401T1 (de) | 2004-11-09 | 2005-10-10 | Ophthalmische emulsion mit einem immunosuppressiven mittel |
Country Status (14)
Country | Link |
---|---|
US (5) | US8298568B2 (de) |
EP (1) | EP1655021B1 (de) |
JP (3) | JP5587936B2 (de) |
CN (3) | CN101056615B (de) |
AT (5) | ATE412400T1 (de) |
DE (5) | DE602004017477D1 (de) |
DK (1) | DK1809237T3 (de) |
ES (4) | ES2314354T3 (de) |
HK (2) | HK1107938A1 (de) |
IL (3) | IL181446A (de) |
MX (2) | MX2007005545A (de) |
NZ (1) | NZ554929A (de) |
PT (2) | PT1809237E (de) |
ZA (1) | ZA200703751B (de) |
Families Citing this family (105)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7655252B2 (en) | 1999-04-28 | 2010-02-02 | The Regents Of The University Of Michigan | Antimicrobial nanoemulsion compositions and methods |
US7767216B2 (en) | 1999-04-28 | 2010-08-03 | The Regents Of The University Of Michigan | Antimicrobial compositions and methods of use |
US8236335B2 (en) | 1999-04-28 | 2012-08-07 | The Regents Of The University Of Michigan | Antimicrobial nanoemulsion compositions and methods |
US20050208083A1 (en) | 2003-06-04 | 2005-09-22 | Nanobio Corporation | Compositions for inactivating pathogenic microorganisms, methods of making the compositons, and methods of use thereof |
ATE412400T1 (de) * | 2004-11-09 | 2008-11-15 | Novagali Pharma Sa | Öl-in-wasser-emulsion mit niedriger konzentration des kationischen mittels und positivem zetapotential |
CA2604392A1 (en) * | 2005-04-11 | 2006-10-19 | Nanobio Corporation | Quaternary ammonium halides for treatment of infectious conditions |
US7297679B2 (en) * | 2005-07-13 | 2007-11-20 | Allergan, Inc. | Cyclosporin compositions |
JP2009504805A (ja) * | 2005-08-09 | 2009-02-05 | ナノバイオ コーポレーション | 抗炎症活性を有するナノエマルジョン組成物 |
US7797337B2 (en) * | 2005-09-29 | 2010-09-14 | Scenera Technologies, Llc | Methods, systems, and computer program products for automatically associating data with a resource as metadata based on a characteristic of the resource |
US11311477B2 (en) | 2006-03-07 | 2022-04-26 | Sgn Nanopharma Inc. | Ophthalmic preparations |
US10137083B2 (en) * | 2006-03-07 | 2018-11-27 | SGN Nanopharma Inc | Ophthalmic preparations |
WO2007103294A2 (en) * | 2006-03-07 | 2007-09-13 | Novavax, Inc. | Nanoemulsions of poorly soluble pharmaceutical active ingredients and methods of making the same |
US7666912B2 (en) | 2006-03-23 | 2010-02-23 | Massachusetts Eye And Ear Infirmary | Compositions and methods for reducing body fat |
PL1891939T3 (pl) * | 2006-07-28 | 2014-01-31 | Santen Sas | Kompozycje zawierające czwartorzędowe związki amonowe |
AU2014201978B2 (en) * | 2006-07-28 | 2016-03-10 | Santen Sas | Compositions containing quaternary ammonium compounds |
US20080026013A1 (en) * | 2006-07-28 | 2008-01-31 | Laura Rabinovich-Guilatt | Compositions containing quaternary ammonium compounds |
WO2008035246A2 (en) | 2006-07-28 | 2008-03-27 | Novagali Pharma Sa | Compositions containing quaternary ammonium compounds |
US9132071B2 (en) * | 2006-07-28 | 2015-09-15 | Santen Sas | Compositions containing quaternary ammonium compounds |
EP1901101A1 (de) | 2006-09-14 | 2008-03-19 | Carl Zeiss SMT AG | Optische Elementeinheit und Verfahren zum Stützen eines optischen Elements |
EP1938801A1 (de) * | 2006-12-22 | 2008-07-02 | Biofrontera Bioscience GmbH | Nanoemulsion |
EP1985298A1 (de) | 2007-04-24 | 2008-10-29 | Azad Pharma AG | Prostaglandinhaltige Öl-in-Wasser-Emulsionen für das Auge |
US8747872B2 (en) | 2007-05-02 | 2014-06-10 | The Regents Of The University Of Michigan | Nanoemulsion therapeutic compositions and methods of using the same |
US8512687B2 (en) * | 2007-07-09 | 2013-08-20 | Novagali Pharma Sa | Oil in water emulsion comprising NSAIDs and quaternary ammonium halides |
US9125807B2 (en) | 2007-07-09 | 2015-09-08 | Incept Llc | Adhesive hydrogels for ophthalmic drug delivery |
US20090018057A1 (en) * | 2007-07-09 | 2009-01-15 | Gregory Lambert | OIL IN WATER EMULSION COMPRISING NSAIDs AND QUATERNARY AMMONIUM HALIDES |
EP2197449A4 (de) * | 2007-10-16 | 2013-10-09 | Sun Pharma Advanced Res Co Ltd | Neuartige ophthalmische zusammensetzungen |
WO2009063081A2 (en) * | 2007-11-14 | 2009-05-22 | Novagali Pharma Sa | Composition comprising at least one nucleosidic moiety as a therapeutic agent, and ckc. |
US7834172B2 (en) * | 2007-11-14 | 2010-11-16 | Novagali Pharma Sa | Composition comprising at least one nucleosidic moiety as a therapeutic agent, and CKC |
EP2077105A1 (de) * | 2008-01-02 | 2009-07-08 | Novagali Pharma SA | Ophthalmische mizellare Zusammensetzung mit erhöhter Stabilität |
EP2077104A1 (de) * | 2008-01-02 | 2009-07-08 | Novagali Pharma SA | Mizellare Zusammensetzungen mit ophtalmischen Anwendungen |
EP2127638A1 (de) * | 2008-05-30 | 2009-12-02 | Santen Pharmaceutical Co., Ltd | Verfahren und Zusammensetzung zur Behandlung von Augenhochdruck und Glaukom |
US9089720B2 (en) * | 2008-09-04 | 2015-07-28 | Santen Pharmaceutical Co., Ltd. | Hair growth promoting agent containing 15,15-difluoroprostaglandin F2α derivative as active ingredient |
WO2010026239A1 (en) * | 2008-09-05 | 2010-03-11 | Ceva Sante Animale Sa | Composition comprising chitosan for ocular administration of vaccine(s) to avians |
US9974844B2 (en) | 2008-11-17 | 2018-05-22 | The Regents Of The University Of Michigan | Cancer vaccine compositions and methods of using the same |
CN102395401B (zh) | 2009-02-12 | 2015-08-19 | 因赛普特有限责任公司 | 经由水凝胶塞的药物递送 |
EP2228058A1 (de) | 2009-03-04 | 2010-09-15 | Novagali Pharma S.A. | Anionische Öl-in-Wasser-Emulsion mit Prostaglandinen und Verwendungen dafür |
EP2228057A1 (de) * | 2009-03-04 | 2010-09-15 | Novagali Pharma S.A. | Kationische Öl-in-Wasser-Emulsionen mit Prostaglandinen und Verwendungen dafür |
WO2010135731A1 (en) * | 2009-05-22 | 2010-11-25 | Kaufman Herbert E | Preparations and methods for ameliorating or reducing presbyopia |
US8299079B2 (en) | 2009-05-22 | 2012-10-30 | Kaufman Herbert E | Preparations and methods for ameliorating or reducing presbyopia |
US20110112198A1 (en) * | 2009-11-09 | 2011-05-12 | Allergan, Inc. | Compositions for enhancing hair growth |
EP2389939A1 (de) | 2010-05-28 | 2011-11-30 | Novagali Pharma S.A. | Verwendung von Prostaglandinen F2alpha und Analoga zur Heilung von Horn- und Bindehautläsionen |
CN103124541B (zh) * | 2010-07-15 | 2015-09-30 | 艾诺维亚股份有限公司 | 眼药物递送 |
US10154923B2 (en) | 2010-07-15 | 2018-12-18 | Eyenovia, Inc. | Drop generating device |
US10272040B2 (en) | 2010-08-12 | 2019-04-30 | Nanyang Technological University | Liposomal formulation for ocular drug delivery |
US8961501B2 (en) | 2010-09-17 | 2015-02-24 | Incept, Llc | Method for applying flowable hydrogels to a cornea |
EP2982373B1 (de) | 2011-01-19 | 2018-06-13 | Topokine Therapeutics, Inc. | Verfahren und zusammensetzungen zur reduzierung von körperfett |
CA2825396C (en) | 2011-01-26 | 2016-09-06 | Allergan, Inc. | Androgen composition for treating an opthalmic condition |
US10307292B2 (en) | 2011-07-18 | 2019-06-04 | Mor Research Applications Ltd | Device for adjusting the intraocular pressure |
US10226417B2 (en) | 2011-09-16 | 2019-03-12 | Peter Jarrett | Drug delivery systems and applications |
CN104039308B (zh) | 2011-11-15 | 2018-06-05 | 阿勒根公司 | 环孢菌素a形式2的可热压性悬浮液 |
US8796222B2 (en) | 2011-11-15 | 2014-08-05 | Allergan, Inc. | Suspensions of cyclosporin A form 2 |
CN109200013A (zh) | 2011-12-05 | 2019-01-15 | 因赛普特有限责任公司 | 医用有机凝胶方法和组合物 |
US8426471B1 (en) | 2011-12-19 | 2013-04-23 | Topokine Therapeutics, Inc. | Methods and compositions for reducing body fat and adipocytes |
US20150299600A1 (en) * | 2012-02-24 | 2015-10-22 | FAIN-Biomedical Inc. | Lubricant Regulating Agent |
DK2887923T3 (da) * | 2012-08-24 | 2023-07-03 | Sun Pharmaceutical Ind Ltd | Oftalmisk opløsning af polyoxyllipid eller polyoxylfedtsyre og behandling af øjentilstande |
SG10201701773UA (en) * | 2012-09-06 | 2017-04-27 | Univ Nanyang Tech | Hyaluronic Acid-Based Drug Delivery Systems |
CN104936595A (zh) | 2012-11-21 | 2015-09-23 | 托普凯恩制药公司 | 局部增加体脂肪的方法和组合物 |
DK2948134T3 (da) | 2013-01-24 | 2020-06-02 | Palvella Therapeutics Inc | Sammensætninger til transdermal indgivelse af mtor-inhibitorer |
WO2014138085A1 (en) | 2013-03-05 | 2014-09-12 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Thermoresponsive hydrogel containing polymer microparticles for noninvasive ocular drug delivery |
ES2799185T3 (es) * | 2013-03-13 | 2020-12-15 | Santen Pharmaceutical Co Ltd | Agente terapéutico para la disfunción meibomiana |
US20140275261A1 (en) * | 2013-03-15 | 2014-09-18 | Dr. Reddy's Laboratories, Inc. | Diclofenac parenteral compositions |
RU2513597C1 (ru) * | 2013-04-17 | 2014-04-20 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт глазных болезней" Российской академии медицинских наук (ФГБУ "НИИГБ" РАМН) | Способ лечения воспалительных состояний переднего отрезка глаза |
NO2753788T3 (de) | 2013-05-10 | 2018-06-16 | ||
WO2014186504A1 (en) | 2013-05-15 | 2014-11-20 | Topokine Therapeutics, Inc. | Methods and compositions for topical delivery of prostaglandins to subcutaneous fat |
US9630909B2 (en) | 2013-06-27 | 2017-04-25 | Mylan Laboratories Ltd | Process for the preparation of nepafenac |
US9956195B2 (en) | 2014-01-07 | 2018-05-01 | Nanyang Technological University | Stable liposomal formulations for ocular drug delivery |
WO2015123272A1 (en) | 2014-02-11 | 2015-08-20 | Dr. Reddy's Laboratories Ltd. | Parenteral compositions of celecoxib |
BR112016018673B1 (pt) | 2014-02-14 | 2023-10-17 | Jingjun Huang | Composição em nanoemulsão de óleo em água estável opticamente clara, método de produção da mesma, e, formulação de carreador |
WO2015189387A1 (en) * | 2014-06-13 | 2015-12-17 | Sanofi | Nanocapsular formulation of active pharmaceutical ingredients |
WO2015200425A1 (en) | 2014-06-27 | 2015-12-30 | Topokine Therapeutics, Inc. | Topical dosage regimen |
EP3233174B1 (de) * | 2014-12-19 | 2021-03-31 | Kemin Industries, Inc. | Intraokulare abgabe bioaktiver moleküle mittels iontophorese |
US11324800B2 (en) | 2015-01-15 | 2022-05-10 | Wellspring Ophthalmics, Inc. | Aqueous suspensions of cyclosporin |
US20200237859A1 (en) | 2019-01-25 | 2020-07-30 | Newport Research, Inc. | Aqueous suspensions of cyclosporin |
WO2016127022A1 (en) * | 2015-02-06 | 2016-08-11 | Foreman James Michael | Preparation of an oil-in-water emulsion for polymer stabilized pharmaceutical formulations |
CN106176600A (zh) * | 2015-05-07 | 2016-12-07 | 上海现代药物制剂工程研究中心有限公司 | 一种前列地尔冻干微乳剂、原料组合物及其制备方法 |
WO2016182926A1 (en) * | 2015-05-08 | 2016-11-17 | Affinsci Inc. | Preparation of nanoemulsions |
FI3373976T3 (fi) | 2015-11-10 | 2024-03-25 | Sun Pharmaceutical Ind Ltd | Topikaalisia formulaatioita ja niiden käyttöjä |
EP4410312A2 (de) | 2016-02-29 | 2024-08-07 | Sun Pharmaceutical Industries Limited | Topische cyclosporinhaltige formulierungen und verwendungen davon |
JP6906899B2 (ja) * | 2016-03-30 | 2021-07-21 | 小林製薬株式会社 | 乳化組成物 |
EP3452152A4 (de) | 2016-05-03 | 2020-01-01 | Pneuma Respiratory, Inc. | Verfahren zur erzeugung und abgabe von tröpfchen an das lungensystem unter verwendung einer tröpfchenabgabevorrichtung |
CA3022916C (en) | 2016-05-03 | 2020-03-10 | Pneuma Respiratory, Inc. | Droplet delivery device for delivery of fluids to the pulmonary system and methods of use |
US11285285B2 (en) | 2016-05-03 | 2022-03-29 | Pneuma Respiratory, Inc. | Systems and methods comprising a droplet delivery device and a breathing assist device for therapeutic treatment |
US11285284B2 (en) | 2016-05-03 | 2022-03-29 | Pneuma Respiratory, Inc. | Methods for treatment of pulmonary lung diseases with improved therapeutic efficacy and improved dose efficiency |
US11285274B2 (en) | 2016-05-03 | 2022-03-29 | Pneuma Respiratory, Inc. | Methods for the systemic delivery of therapeutic agents to the pulmonary system using a droplet delivery device |
US11395853B2 (en) | 2016-06-23 | 2022-07-26 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Biomimetic drug delivery of an immunomodulatory agent for the treatment of ocular conditions |
SI3266446T1 (sl) * | 2016-07-07 | 2019-02-28 | Laboratorios Salvat, S.A. | Oftalmična sestava, obsegajoča ricinusovo olje in triglicerid s srednjo verigo |
CN106782348A (zh) * | 2017-01-04 | 2017-05-31 | 深圳市华星光电技术有限公司 | 一种led背光驱动电路及液晶显示器 |
IL267869B2 (en) | 2017-01-06 | 2023-10-01 | Palvella Therapeutics Inc | Non-aqueous preparations of mTOR inhibitors and methods of use |
CA3064005C (en) | 2017-05-19 | 2023-03-07 | Pneuma Respiratory, Inc. | Dry powder delivery device and methods of use |
JP7278969B2 (ja) * | 2017-05-30 | 2023-05-22 | エキシモア・リミテッド | ドライアイ症候群を治療するための抗生物質マクロライドを送達する組成物および方法 |
KR102643190B1 (ko) | 2017-06-10 | 2024-03-04 | 아이노비아 인코포레이티드 | 유체를 취급하기 위한, 그리고 눈에 유체를 전달하기 위한 디바이스들 |
CA3077475A1 (en) | 2017-10-04 | 2019-04-11 | Pneuma Respiratory, Inc. | Electronic breath actuated in-line droplet delivery device and methods of use |
EP4344719A3 (de) | 2017-10-17 | 2024-06-05 | Pneuma Respiratory, Inc. | Nasale arzneimittelabgabevorrichtung und verwendungsverfahren |
US11253480B2 (en) | 2017-10-30 | 2022-02-22 | University of Pittsburgh—of the Commonwealth System of Higher Education | Treatment of ocular conditions utilizing a histone/protein deacetylase inhibitor |
CN111479604B (zh) | 2017-11-08 | 2022-12-30 | 精呼吸股份有限公司 | 具有小体积安瓿的电动呼吸致动直列液滴输送装置及使用方法 |
CA3092016A1 (en) * | 2018-02-26 | 2020-08-21 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd | Drug delivery systems |
US11000513B2 (en) | 2018-07-02 | 2021-05-11 | Palvella Therapeutics, Inc. | Anhydrous compositions of mTOR inhibitors and methods of use |
CN109010268B (zh) * | 2018-09-28 | 2020-07-10 | 湖北远大天天明制药有限公司 | 一种提高氯霉素稳定性的眼用组合物及其制备方法 |
CA3119037A1 (en) | 2018-12-11 | 2020-06-18 | Disruption Labs Inc. | Compositions for the delivery of therapeutic agents and methods of use and making thereof |
CN110237233B (zh) * | 2019-07-30 | 2021-01-15 | 沈阳兴齐眼药股份有限公司 | 一种含有环孢素的眼用药物组合物、其制备方法及用途 |
EP4069220A4 (de) * | 2019-12-04 | 2024-04-24 | Restore Vision, LLC. | Ophthalmische formulierungen zur behandlung von presbyopie |
CN116437909A (zh) * | 2020-06-10 | 2023-07-14 | 迪斯拉普申实验室公司 | 用于递送治疗剂的组合物及其使用方法和制备方法 |
WO2022271848A1 (en) | 2021-06-22 | 2022-12-29 | Pneuma Respiratory, Inc. | Droplet delivery device with push ejection |
CN113577024B (zh) * | 2021-08-20 | 2023-05-05 | 山西利普达医药科技有限公司 | 一种眼用组合物及其制备方法和应用 |
CN116407499B (zh) * | 2021-12-29 | 2024-10-25 | 辅必成(上海)医药科技有限公司 | 一种他克莫司眼用乳剂及其制备方法 |
Family Cites Families (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4599353A (en) * | 1982-05-03 | 1986-07-08 | The Trustees Of Columbia University In The City Of New York | Use of eicosanoids and their derivatives for treatment of ocular hypertension and glaucoma |
JPH0818989B2 (ja) * | 1984-01-12 | 1996-02-28 | 株式会社ミドリ十字 | 脂肪乳剤中のプロスタグランジンの安定化方法 |
US4839342A (en) * | 1987-09-03 | 1989-06-13 | University Of Georgia Research Foundation, Inc. | Method of increasing tear production by topical administration of cyclosporin |
JP2602964B2 (ja) | 1989-10-16 | 1997-04-23 | 裕 水島 | プロスタグランジン類縁体およびその脂肪乳剤 |
IL101241A (en) * | 1992-03-16 | 1997-11-20 | Yissum Res Dev Co | Pharmaceutical or cosmetic composition comprising stabilized oil-in-water type emulsion as carrier |
IL103907A0 (en) * | 1992-11-27 | 1993-04-04 | Pharmos Corp | Ophthalmic compositions |
WO1994005298A1 (en) * | 1992-08-28 | 1994-03-17 | Pharmos Corporation | Submicron emulsions as ocular drug delivery vehicles |
US5688819A (en) * | 1992-09-21 | 1997-11-18 | Allergan | Cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents |
JP3551977B2 (ja) * | 1993-04-08 | 2004-08-11 | ライオン株式会社 | 安定なビタミンa類及びビタミンe類可溶化点眼剤 |
FI108514B (fi) * | 1993-06-25 | 2002-02-15 | Cusi Lab | Polymeerimembraanien käyttö sellaisten farmaseuttisten liuosten jakelussa, jotka sisältävät kvaternäärisiä ammoniumyhdisteitä |
US5510383A (en) * | 1993-08-03 | 1996-04-23 | Alcon Laboratories, Inc. | Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension |
DK0756489T3 (da) * | 1994-06-01 | 1999-12-06 | Yuhan Corp | Cyclosporinholdigt præparat og fremgangsmåde til fremstillingen af dette |
ES2094688B1 (es) * | 1994-08-08 | 1997-08-01 | Cusi Lab | Manoemulsion del tipo de aceite en agua, util como vehiculo oftalmico y procedimiento para su preparacion. |
US5631287A (en) * | 1994-12-22 | 1997-05-20 | Alcon Laboratories, Inc. | Storage-stable prostaglandin compositions |
US6011062A (en) * | 1994-12-22 | 2000-01-04 | Alcon Laboratories, Inc. | Storage-stable prostaglandin compositions |
US5767153A (en) * | 1995-06-07 | 1998-06-16 | Insite Vision Incorporated | Sustained release emulsions |
JP3410364B2 (ja) * | 1997-05-14 | 2003-05-26 | 千寿製薬株式会社 | ジフルプレドナート含有組成物 |
US6114319A (en) | 1997-05-14 | 2000-09-05 | Senju Pharmaceutical Co., Ltd. | Compositions containing difluprednate |
US6066671A (en) * | 1997-12-19 | 2000-05-23 | Alcon Laboratories, Inc. | Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides |
US6225348B1 (en) * | 1998-08-20 | 2001-05-01 | Alfred W. Paulsen | Method of treating macular degeneration with a prostaglandin derivative |
WO2000038663A2 (en) * | 1998-12-24 | 2000-07-06 | Alcon Laboratories, Inc. | Ep4 receptor agonists for treatment of dry eye |
US20020136771A1 (en) * | 1998-12-31 | 2002-09-26 | Amitee Cosmetics, Inc. | Stabilized ascorbic acid composition |
FR2823441B1 (fr) * | 2001-04-12 | 2004-09-10 | Thea Lab | Composition pharmaceutique a base de macrolides pour application locale en ophtalmologie et son procede de preparation |
CA2443937A1 (en) * | 2001-04-23 | 2002-10-31 | Randall D. Glickman | Prostanoids augment ocular drug penetration |
EP1528937B1 (de) * | 2001-06-05 | 2016-08-10 | The Regents Of The University Of Michigan | Nanoemulsionsvakzine |
US6872705B2 (en) * | 2001-07-13 | 2005-03-29 | Allergan, Inc. | Use of antimicrobial peptides as preservatives in ophthalmic preparations, including solutions, emulsions, and suspensions |
JP2005513097A (ja) * | 2001-11-01 | 2005-05-12 | イサム・リサーチ・デベロツプメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシテイ・オブ・エルサレム | ドライアイ治療方法および組成物 |
US6656460B2 (en) * | 2001-11-01 | 2003-12-02 | Yissum Research Development | Method and composition for dry eye treatment |
KR100446960B1 (ko) | 2001-12-04 | 2004-09-01 | 김종국 | 프로스타글란딘 e1을 포함하는 온도감응성 에멀젼 외용제조성물 |
US20030165545A1 (en) * | 2002-01-30 | 2003-09-04 | Allergan, Inc. | Ophthalmic compositions including oil-in-water emulsions, and methods for making and using same |
US20050124699A1 (en) * | 2002-07-02 | 2005-06-09 | Wakamoto Pharmaceutical Co., Ltd. | Drugs for treating or preventing disorders of corneal and/or conjunctival epithelial cells |
KR101027454B1 (ko) | 2002-08-23 | 2011-04-06 | 산텐 세이야꾸 가부시키가이샤 | 라타노프로스트를 유효 성분으로 하는 안정한 점안액 |
KR20050057251A (ko) | 2002-09-09 | 2005-06-16 | 산텐 세이야꾸 가부시키가이샤 | 라타노프로스트를 유효 성분으로 하는 투명한 점안액 |
US20040115234A1 (en) * | 2002-09-24 | 2004-06-17 | Gewirtz Joan T. | Cosmetic composition |
US7074827B2 (en) * | 2002-10-24 | 2006-07-11 | Sucampo Ag (Usa) Inc. | Method for treating ocular hypertension and glaucoma |
JP4361294B2 (ja) * | 2003-02-25 | 2009-11-11 | ロート製薬株式会社 | ケトチフェン含有組成物 |
JP4694773B2 (ja) * | 2003-06-06 | 2011-06-08 | ロート製薬株式会社 | 粘膜適用液状組成物 |
US20050059583A1 (en) * | 2003-09-15 | 2005-03-17 | Allergan, Inc. | Methods of providing therapeutic effects using cyclosporin components |
JP5382972B2 (ja) * | 2003-12-26 | 2014-01-08 | ロート製薬株式会社 | 粘度低下が防止された組成物 |
US20050175651A1 (en) * | 2004-01-09 | 2005-08-11 | L'oreal | Aqueous dispersion of nanocapsules with an oily core |
ATE439123T1 (de) | 2004-07-02 | 2009-08-15 | Novagali Pharma Sa | Verwendung von emulsionen zur intra- und periocularen injection |
JP4999304B2 (ja) * | 2004-09-27 | 2012-08-15 | ロート製薬株式会社 | ヒアルロン酸又はその塩を含有する粘膜適用組成物 |
ATE412400T1 (de) * | 2004-11-09 | 2008-11-15 | Novagali Pharma Sa | Öl-in-wasser-emulsion mit niedriger konzentration des kationischen mittels und positivem zetapotential |
EP1929996B1 (de) * | 2004-11-09 | 2011-02-16 | Novagali Pharma S.A. | Ophthalmische Emulsionen mit einem immunsuppressiven Mittel |
US20090169629A1 (en) * | 2008-01-02 | 2009-07-02 | Novagali Pharma Sa | Micellar compositions with ophthalmic applications |
US20090170944A1 (en) * | 2008-01-02 | 2009-07-02 | Novagali Pharma Sa | Ophthalmic micellar compositions with enhanced stability |
KR20110010788A (ko) * | 2008-05-28 | 2011-02-07 | 알콘 리서치, 리미티드 | 자기보존 에멀젼 |
EP2228058A1 (de) * | 2009-03-04 | 2010-09-15 | Novagali Pharma S.A. | Anionische Öl-in-Wasser-Emulsion mit Prostaglandinen und Verwendungen dafür |
EP2228057A1 (de) * | 2009-03-04 | 2010-09-15 | Novagali Pharma S.A. | Kationische Öl-in-Wasser-Emulsionen mit Prostaglandinen und Verwendungen dafür |
EP2389939A1 (de) * | 2010-05-28 | 2011-11-30 | Novagali Pharma S.A. | Verwendung von Prostaglandinen F2alpha und Analoga zur Heilung von Horn- und Bindehautläsionen |
-
2004
- 2004-11-09 AT AT04292645T patent/ATE412400T1/de not_active IP Right Cessation
- 2004-11-09 EP EP04292645A patent/EP1655021B1/de not_active Expired - Lifetime
- 2004-11-09 ES ES04292645T patent/ES2314354T3/es not_active Expired - Lifetime
- 2004-11-09 DE DE602004017477T patent/DE602004017477D1/de not_active Expired - Lifetime
- 2004-11-18 US US10/991,346 patent/US8298568B2/en active Active
-
2005
- 2005-10-10 DE DE602005011480T patent/DE602005011480D1/de active Active
- 2005-10-10 CN CN2005800383296A patent/CN101056615B/zh active Active
- 2005-10-10 DE DE602005012136T patent/DE602005012136D1/de active Active
- 2005-10-10 AT AT08102553T patent/ATE498392T1/de not_active IP Right Cessation
- 2005-10-10 DK DK05795930T patent/DK1809237T3/da active
- 2005-10-10 AT AT05795930T patent/ATE418964T1/de not_active IP Right Cessation
- 2005-10-10 AT AT05800012T patent/ATE415942T1/de not_active IP Right Cessation
- 2005-10-10 US US11/667,129 patent/US8273362B2/en active Active
- 2005-10-10 DE DE602005010733T patent/DE602005010733D1/de active Active
- 2005-10-10 MX MX2007005545A patent/MX2007005545A/es active IP Right Grant
- 2005-10-10 MX MX2007003045A patent/MX2007003045A/es active IP Right Grant
- 2005-10-10 PT PT05795930T patent/PT1809237E/pt unknown
- 2005-10-10 ES ES05800012T patent/ES2319129T3/es active Active
- 2005-10-10 US US11/665,066 patent/US8298569B2/en active Active
- 2005-10-10 PT PT05802097T patent/PT1809238E/pt unknown
- 2005-10-10 ZA ZA200703751A patent/ZA200703751B/xx unknown
- 2005-10-10 US US11/667,355 patent/US8372434B2/en active Active
- 2005-10-10 ES ES05795930T patent/ES2320574T3/es active Active
- 2005-10-10 DE DE602005026464T patent/DE602005026464D1/de active Active
- 2005-10-10 AT AT05802097T patent/ATE412401T1/de not_active IP Right Cessation
- 2005-10-10 ES ES05802097T patent/ES2317319T3/es active Active
- 2005-10-10 NZ NZ554929A patent/NZ554929A/en unknown
- 2005-10-10 CN CNA2005800300698A patent/CN101014317A/zh active Pending
- 2005-10-10 CN CN201310241506.7A patent/CN103356481B/zh active Active
-
2006
- 2006-10-10 US US12/089,609 patent/US20080268020A1/en not_active Abandoned
-
2007
- 2007-02-20 IL IL181446A patent/IL181446A/en active IP Right Grant
- 2007-05-01 IL IL182897A patent/IL182897A/en unknown
-
2008
- 2008-01-21 HK HK08100777.1A patent/HK1107938A1/xx unknown
- 2008-03-27 IL IL190497A patent/IL190497A/en active IP Right Grant
- 2008-06-17 HK HK08106646.7A patent/HK1112411A1/xx unknown
-
2012
- 2012-04-05 JP JP2012086806A patent/JP5587936B2/ja active Active
- 2012-05-15 JP JP2012111941A patent/JP5773941B2/ja active Active
-
2014
- 2014-02-19 JP JP2014029816A patent/JP5894202B2/ja active Active
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE412400T1 (de) | Öl-in-wasser-emulsion mit niedriger konzentration des kationischen mittels und positivem zetapotential | |
EA200600877A1 (ru) | Наночастицы для доставки лекарств | |
WO2008013785A3 (en) | Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening | |
WO2007137237A3 (en) | Treatment of protein misfolding | |
BRPI0411306A (pt) | composições farmacêuticas compreendendo compostos ativos de vitamina d | |
WO2006108405A3 (de) | Nanopartikel-wirkstoff-konjugate | |
BRPI0607728A2 (pt) | complexo de lipoproteìna carregado reconstituìdo, composição farmacêutica, e, uso de um complexo de lipoproteìna carregado | |
BRPI0906866A2 (pt) | métodos e composições para administração oral de agentes terapêutico de proteína e peptídeo | |
EP1929996A3 (de) | Ophthalmische Emulsionen mit einem immunsuppressiven Mittel | |
WO2008070538A3 (en) | Micellar nanoparticles comprising botulinum toxin | |
EP2481409A3 (de) | Nanopartikel mit Rapamycin und Albumin als Antikrebsmittel | |
UA101309C2 (ru) | Антагонисты активина-actrii и их применение для повышения уровня эритроцитов | |
DK1429731T3 (da) | Nanopartikelformuleringer indeholdende insulin | |
MD20070267A (en) | Gastroresistant pharmaceutical formulation containing rifaximin | |
DE60216305D1 (de) | Zusammensetzungen zur verabreichung von arzneimittelkombinationen | |
TW200613004A (en) | External preparation of solid/oil type | |
ATE422880T1 (de) | Heterofunktionelle copolymere von glycerol und polyethylenglykol, ihre konjugate und zusammensetzungen | |
WO2008085556A3 (en) | Surfactant-free nanoparticles for drug delivery | |
ATE513562T1 (de) | Nicht-spezifische immunstimulierende mittel | |
ATE507818T1 (de) | Orale verabreichung eines calcitonins | |
WO2008048205A3 (en) | Method for delivering hydrophobic drugs via nanocrystal formulations | |
ATE508740T1 (de) | Mittel zur verringerung von müdigkeit | |
Sousa et al. | Smart delivery systems for microbial biofilm therapy: dissecting design, drug release and toxicological features | |
DE60310605D1 (de) | Nanoteilchen zur verabreichung von wirkstoffen, verfahren zur herstellung dieser teilchen und diese enthaltende zusammensetzung | |
CY1109541T1 (el) | Φαρμακευτικη συνταγοποιηση για την θεραπεια οστεοαρθριτιδας η οποια περιεχει κλοδρονικο οξυ και υαλουρονικο οξυ |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |