AR011697A1 - Composiciones farmaceuticas, uso de lamivudina en la manufactura de tales composiciones farmaceuticas. - Google Patents
Composiciones farmaceuticas, uso de lamivudina en la manufactura de tales composiciones farmaceuticas.Info
- Publication number
- AR011697A1 AR011697A1 ARP980101317A ARP980101317A AR011697A1 AR 011697 A1 AR011697 A1 AR 011697A1 AR P980101317 A ARP980101317 A AR P980101317A AR P980101317 A ARP980101317 A AR P980101317A AR 011697 A1 AR011697 A1 AR 011697A1
- Authority
- AR
- Argentina
- Prior art keywords
- lamivudine
- pharmaceutical compositions
- manufacture
- ethanol
- substantially free
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Composicion farmacéutica, sustancialmente libre de etanol y ácido etilendiaminotetraacético, que contienen (2R, cis)-4-amino-1-(2-hidroximetil-1,3-oxathiolan-5-il)-(1H)-pirimidin-2-ona ((-)-2, 3-didesoxi, 3-thiacitidina , Epivir, lamivudina );proceso para su manufactura y el uso de la lamivudina enla manufactura de tales formulaciones farmacéuticas, dichas formulaciones son utiles en el tratamiento o profilaxis de las retrovirales de humanos, y puedenser utilizados en terapia con otros agentes terapéuticos. En una realizacion composicion farmacéutica, substancialmente libre de etanol y ácidoetilendiaminotetraacético, comprende lamivudina o un derivado farmacéuticamente aceptable de la misma, metilparabedno, y propilparabeno, lacomposicion tieneun pH mayor que 5.5.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4235397P | 1997-03-24 | 1997-03-24 | |
GBGB9706295.4A GB9706295D0 (en) | 1997-03-26 | 1997-03-26 | Lamivudine formulation |
Publications (1)
Publication Number | Publication Date |
---|---|
AR011697A1 true AR011697A1 (es) | 2000-08-30 |
Family
ID=26311267
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP980101317A AR011697A1 (es) | 1997-03-24 | 1998-03-23 | Composiciones farmaceuticas, uso de lamivudina en la manufactura de tales composiciones farmaceuticas. |
Country Status (40)
Country | Link |
---|---|
US (1) | US6004968A (es) |
EP (1) | EP0969815B1 (es) |
JP (1) | JP3264937B2 (es) |
KR (1) | KR100484695B1 (es) |
CN (1) | CN1191061C (es) |
AP (1) | AP1141A (es) |
AR (1) | AR011697A1 (es) |
AT (1) | ATE295150T1 (es) |
AU (1) | AU728461B2 (es) |
BG (1) | BG64690B1 (es) |
BR (1) | BR9808060B1 (es) |
CA (1) | CA2286126C (es) |
CO (1) | CO4980849A1 (es) |
CY (1) | CY2569B1 (es) |
CZ (1) | CZ298008B6 (es) |
DE (1) | DE69830154T2 (es) |
EA (1) | EA001990B1 (es) |
EE (1) | EE03996B1 (es) |
ES (1) | ES2239802T3 (es) |
HK (1) | HK1022853A1 (es) |
HN (1) | HN1998000045A (es) |
HR (1) | HRP980154B1 (es) |
HU (1) | HU225600B1 (es) |
ID (1) | ID29294A (es) |
IL (1) | IL131917A0 (es) |
IS (1) | IS2515B (es) |
MY (1) | MY116242A (es) |
NO (1) | NO326719B1 (es) |
NZ (1) | NZ337798A (es) |
PA (1) | PA8449301A1 (es) |
PE (1) | PE61699A1 (es) |
PL (1) | PL190505B1 (es) |
PT (1) | PT969815E (es) |
RS (1) | RS49772B (es) |
SI (1) | SI0969815T1 (es) |
SK (1) | SK283417B6 (es) |
SV (1) | SV1998000040A (es) |
TW (1) | TW536403B (es) |
UY (1) | UY24930A1 (es) |
WO (1) | WO1998042321A2 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CO4900074A1 (es) | 1996-06-25 | 2000-03-27 | Glaxo Group Ltd | Combinaciones antivirales |
US6018044A (en) * | 1998-01-02 | 2000-01-25 | Roche Vitamins Inc. | Light screening compositions |
US6432966B2 (en) * | 1999-10-29 | 2002-08-13 | Smithkline Beecham Corporation | Antiviral combinations |
JP2003039582A (ja) * | 2001-07-19 | 2003-02-13 | Three M Innovative Properties Co | 湿潤防滑性シート及び湿潤防滑構造体 |
US6855346B2 (en) * | 2001-10-05 | 2005-02-15 | Tzu-Sheng Wu | Pharmaceutical composition having prophylactic effects on lamivudine-related disease relapse and drug resistance and methods of using the same |
MY131488A (en) * | 2002-04-08 | 2007-08-30 | Bristol Myers Squibb Co | Low dose liquid entecavir formulations and use |
KR101235507B1 (ko) * | 2003-02-28 | 2013-02-20 | 추가이 세이야쿠 가부시키가이샤 | 단백질을 함유하는 안정화 제제 |
US20040228804A1 (en) * | 2003-05-16 | 2004-11-18 | Jones Alonzo H. | Nasal administration of xylitol to a non-human mammal |
PE20060484A1 (es) * | 2004-07-14 | 2006-07-06 | Ucb Farchim Sa | Preparaciones farmaceuticas liquidas que comprenden un compuesto de benzhidril piperizina |
CN100427082C (zh) * | 2005-08-02 | 2008-10-22 | 盛华(广州)医药科技有限公司 | 羟基苯甲酸酯及其类似物在制备预防和治疗病毒性感染药物中的应用 |
GB2470494B (en) * | 2008-01-17 | 2012-08-08 | Univ Holy Ghost Duquesne | Antiretroviral drug formulations for treatment of children exposed to HIV/AIDS |
RU2587782C1 (ru) * | 2015-01-19 | 2016-06-20 | Общество с ограниченной ответственностью "Трейдсервис" | Стабильная фармацевтическая композиция ламивудина |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5047407A (en) * | 1989-02-08 | 1991-09-10 | Iaf Biochem International, Inc. | 2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties |
CZ285232B6 (cs) * | 1991-05-16 | 1999-06-16 | Glaxo Group Limited | Protivirové směsi |
GB9111902D0 (en) * | 1991-06-03 | 1991-07-24 | Glaxo Group Ltd | Chemical compounds |
GB9503850D0 (en) * | 1995-02-25 | 1995-04-19 | Glaxo Group Ltd | Medicaments |
MY115461A (en) * | 1995-03-30 | 2003-06-30 | Wellcome Found | Synergistic combinations of zidovudine, 1592u89 and 3tc |
GB9605293D0 (en) * | 1996-03-13 | 1996-05-15 | Glaxo Group Ltd | Medicaments |
-
1998
- 1998-03-16 TW TW087103841A patent/TW536403B/zh not_active IP Right Cessation
- 1998-03-20 EA EA199900757A patent/EA001990B1/ru not_active IP Right Cessation
- 1998-03-20 US US09/044,896 patent/US6004968A/en not_active Expired - Lifetime
- 1998-03-20 NZ NZ337798A patent/NZ337798A/xx not_active IP Right Cessation
- 1998-03-20 ES ES98919120T patent/ES2239802T3/es not_active Expired - Lifetime
- 1998-03-20 PA PA19988449301A patent/PA8449301A1/es unknown
- 1998-03-20 EE EEP199900440A patent/EE03996B1/xx unknown
- 1998-03-20 AT AT98919120T patent/ATE295150T1/de active
- 1998-03-20 CA CA002286126A patent/CA2286126C/en not_active Expired - Lifetime
- 1998-03-20 CO CO98015975A patent/CO4980849A1/es unknown
- 1998-03-20 DE DE69830154T patent/DE69830154T2/de not_active Expired - Lifetime
- 1998-03-20 HU HU0002982A patent/HU225600B1/hu unknown
- 1998-03-20 PT PT98919120T patent/PT969815E/pt unknown
- 1998-03-20 KR KR10-1999-7008690A patent/KR100484695B1/ko not_active IP Right Cessation
- 1998-03-20 HN HN1998000045A patent/HN1998000045A/es unknown
- 1998-03-20 SV SV1998000040A patent/SV1998000040A/es active IP Right Grant
- 1998-03-20 MY MYPI98001227A patent/MY116242A/en unknown
- 1998-03-20 IL IL13191798A patent/IL131917A0/xx not_active IP Right Cessation
- 1998-03-20 CN CNB988051222A patent/CN1191061C/zh not_active Expired - Lifetime
- 1998-03-20 SI SI9830767T patent/SI0969815T1/xx unknown
- 1998-03-20 CZ CZ0340399A patent/CZ298008B6/cs not_active IP Right Cessation
- 1998-03-20 PE PE1998000203A patent/PE61699A1/es not_active IP Right Cessation
- 1998-03-20 JP JP54442598A patent/JP3264937B2/ja not_active Expired - Lifetime
- 1998-03-20 BR BRPI9808060-1A patent/BR9808060B1/pt not_active IP Right Cessation
- 1998-03-20 WO PCT/EP1998/001626 patent/WO1998042321A2/en active IP Right Grant
- 1998-03-20 RS YUP-477/99A patent/RS49772B/sr unknown
- 1998-03-20 PL PL98336038A patent/PL190505B1/pl unknown
- 1998-03-20 ID IDW991096A patent/ID29294A/id unknown
- 1998-03-20 SK SK1299-99A patent/SK283417B6/sk not_active IP Right Cessation
- 1998-03-20 AP APAP/P/1999/001657A patent/AP1141A/en active
- 1998-03-20 AU AU72084/98A patent/AU728461B2/en not_active Expired
- 1998-03-20 EP EP98919120A patent/EP0969815B1/en not_active Expired - Lifetime
- 1998-03-23 UY UY24930A patent/UY24930A1/es not_active IP Right Cessation
- 1998-03-23 HR HR980154A patent/HRP980154B1/xx not_active IP Right Cessation
- 1998-03-23 AR ARP980101317A patent/AR011697A1/es active IP Right Grant
-
1999
- 1999-09-17 IS IS5184A patent/IS2515B/is unknown
- 1999-09-23 NO NO994619A patent/NO326719B1/no not_active IP Right Cessation
- 1999-10-18 BG BG103818A patent/BG64690B1/bg unknown
-
2000
- 2000-04-07 HK HK00102154A patent/HK1022853A1/xx not_active IP Right Cessation
-
2006
- 2006-11-09 CY CY0600032A patent/CY2569B1/xx unknown
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Legal Events
Date | Code | Title | Description |
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FG | Grant, registration |