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The hygiene hypothesis is about infectious agents, not toxic chemicals.

Hygiene doesn't matter that much. Humans evolved in environments full of pathogens, and most people survived. You'll probably be fine even without obsessive cleaning. There is some evidence that living in overly sterile environments is a risk factor for autoimmune diseases.

Waiting a day for a credit card isn't the issue. Many auto repair shops now offer instant financing through partnerships with third-party lenders. The problem is that the customers have low credit scores and don't qualify for regular loans.

You are right, and I'll add something, too: the 3rd party financiers will sometimes lend to the low credit score people, but they charge high rates like the payday lenders

And on the point, financing your home appliances is a popular thing (but please, pay up front!)

That's not true. If you buy a fitness tracker from Garmin you can download FIT files with all your data either directly from the device or through their free online service. The format is documented and you're allowed to use your own data however you like.

Most JRE sponsors were smaller companies targeting niche markets. He didn't have any mass market brands like Starbucks or Chevrolet.

Honest Q, but do any mass market brands like that advertise on podcasts?

It seems like all I hear are the usual suspects: Me Undies, Blue Apron, etc.

Why would they? They got enough money and reach to go directly on platforms themselves...

On other hand, I'm not entirely sure how I feel about the companies marketing on things like pod casts... Some pretty famous ones don't seem to be too special products, see Raid Shadowlegends, Raycon and all of the VPN providers...

There is a semi-open standard and protocol for fitness tracking: the FIT file format and ANT+ for wireless networking. However most devices which support those standards like Garmin generally require the use of a proprietary mobile app for initial setup. Once you finish that you can uninstall the app.

The workout domain has already standardized on the FIT file format. Pretty much all fitness trackers and bike computers use it for recording activities. It isn't fully open but anyone can license the SDK.


There is free open source software like GoldenCheetah which can read those comes so you don't have to depend on proprietary online services.


If you use a smaller font then you can fit more text on the page, but it's hard to read.

You can't lose it quickly, at least not in a sustainable way. But you can lose it slowly just like other types of fat. Exercise more, eat less, and in particular reduce your sugar intake. There is some evidence that stress also causes accumulation of visceral fat so if you can find a way to relax that might help.

I always think that this idea of "losing fat quickly" is kind of interesting. If you think about it, one year of your life is, on average, barely over a percent of your entire lifespan.

If you lifted weights or ran ~5 days a week for a year and ate appropriately, most people would probably end up looking like models. And that's just one year. To me, that's pretty darn quick. Basically, anything else of value takes like way longer: playing an instrument, getting good at a sport, getting an education. If you really think about it, the time investment is actually pretty minimal.

its more complicated than that depending on your life.

You will never look like a model by just lifting weights and running. You need a propper diet plan and a life that supports it.

Going on dinner with your friend? that will be a no for a year.

Having a bussiness lunch meeting with clients or bosses? Thats a no for a year.

Skipping a week or more of lifing because of unexpected life reasons? Thats a no for a year.

Guarantee a majority of your sleep to be of good quality for a whole year? Very few can do that.

Being on a caloric deficit and maintaining a high protein intake every day for a whole year? That is really hard and requires you to have no unplanned events for a whole year.

Getting in a situation where you have no real good options for your diet plan, you need to make sure never to get there for a year.

If your goal is "just" to loose weight its a bit easier but still a lot of hard work with no compromises for a year, and if you want to look like a model then you need hard work and good genetics to support that.

The time investment depends a whole lot on external factors and its never minimal.

> Going on dinner with your friend? that will be a no for a year.

> Having a bussiness lunch meeting with clients or bosses? Thats a no for a year.

> Skipping a week or more of lifing because of unexpected life reasons? Thats a no for a year

> Being on a caloric deficit and maintaining a high protein intake every day for a whole year? That is really hard and requires you to have no unplanned events for a whole year.

All of those points are incredibly wrong. People are able to stay fit, lean, and healthy without becoming some robotic fool who survives on water and protein powder.

Tracking your TDEE and macros is very simple, and not restrictive at all. One can drink beer, eat pizza and candy, and retain a great physique with ease. It requires only that you don't go overboard when indulging. One doesn't have to be in a caloric deficit every single day. As long as one is in cal-def a majority of the time, it's fine. As long as they don't shovel enough food into their mouth on their 'bad' days, to undo all the hard work from the 'good' days, it works out fine.

One can also easily take weeks off. In fact, every athlete should take weeks off. Deloading is not what I'm referring to. I'm talking about taking an entire week, or even two, off and doing nothing. It's healthy, and even necessary for long-term consistency and success.

Why are you convinced that being fit and lean is some incredibly hard task? It's not. All you're doing is convincing people that they can't accomplish what they can; relatively easily, I might add.

Some of those are definitely a bit exaggerated, perhaps depending on your conception of model. You're not going to destroy your physique most of the time by having an impromptu lunch every so often, especially if you're already struggling to get enough calories to support muscle growth.

No surprise there. Visceral fat has has long been associated with a higher risk of respiratory diseases. But it's good to see this confirmed for COVID-19.


Your link is about 'belly fat', which is not visceral fat, but rather subcutaneous (under the surface of the skin, as opposed to internally around the organs).

Intuitively, it would seem that visceral (internal) fat might affect lung function more, but as the article states, the mechanism of impairment is not clear.

Seems like it's both actually, the more pronounced of which is visceral which seems to make up most of a beer belly.


Your point probably stands, but COVID is not a respiratory disease. It's a vascular disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556303/


It's largely called SARS-CoV-2 because, surprise, it's in the coronavirus family that causes SARS. Yes, it is a respiratory disease, but what we've learned in the last year is that the worst respiratory effects from this disease aren't from it infecting pneumocytes (that's how it spreads) but from the emboli that it creates which then block the vasculature of the lungs.

I'd suggest this lecture by Dr. Seheult of MedCram which dates back to around the time we started discoverying the concerning underlying pathologies of the disease process:


This is also one of the possible explanations for the appearances of rash-like lesions in the extremities of younger populations who are otherwise asymptomatic: Capillary vasculature becoming blocked by the formation of emboli creating a redness in the skin is another feature of a disease that is primarily vascular in nature. Not to mention the increased risk of stroke.

The correct answer is that it's "kind of both" but that the damaging effects from SARS-CoV-2 are less a consequence of destruction of lung cells, as was originally thought, and more a function of blocking the vasculature that carry away oxygen.

Yes, I'm sure. Continue reading, please.

Worth mentioning that one of the authors happens to be on the board of a biotech developing a stroke product.

Most people infected with the COVID-19 virus will experience mild to moderate respiratory illness and recover without requiring special treatment.

But then again, if it's damaging the vascular system then it's also a kidney disease.

25% of each stroke volume out of the heart goes to the kidneys. Anything that damages the vascular system will strain the heart leading to higher blood pressure, which will damage the kidneys.

Poor kidney clearance will increase the incidence of joint diseases like gout and arthritis.

COVID-19 is a joint disease.

You know what structures also have ACE2 receptors that SARS-CoV-2 attacks?

The endothelial cells.

Guess how SARS-CoV-2 causes the formation of emboli that fundamentally result in blocking the lung vasculature? By attacking the endothelium.

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