Autocrine vitamin D signaling switches off pro-inflammatory programs of cells: https://www.nature.com/articles/s41590-021-01080-3
1. This says nothing about Vitamin D as a cure once you got infected. It might work, or it might not, but this study simply does not address the question at all.
Huh? Everyone I know who thinks vitamin D might be helpful says you need to supplement with it on a consistent, ongoing basis, not try to take big catch-up doses once you get sick or wind up in the hospital. Given how safe and cheap it is (and that adequate vitamin D levels may be associated with a range of other improved health outcomes as well), even a 25% reduction in those risks would be a big deal.
You end up with aggressive, last-resort measures like extended lockdowns.
Hence my point that there is minimal downside to being overly cautious when you first hear about new variants.
Your entire framing of these policy choices as inevitable and the only option is baseless. Australia and New Zealand used to be held up as the shining lights of "just act fast enough and you can avoid the need for any sustained restrictions" and now we are seeing just how well kicking the can in that way actually works, and the lengths that must be gone to keep kicking it.
See this pattern all the time in both technical and people side all the time.
“You should never estimate using time”
“Don’t start new work until all the teams sprint commitments are completed”
In a word it is arrogance with a twist of ignorance.
Ignorance that complex systems of humans and code don’t follow perfect dogmatic rules.
It might be ok for junior devs to be a bit like this but always add a pinch of “most of the time, but when experienced you’ll know when to ignore the rule”
Ignoring some unwritten or written dogma is often what makes for a competitive advantage.
Let your competitor drown in EnumClassFactorys .
I think the best authoritative-sounding counter-quip is "Best practices are best not practiced."
I'm just curious, did you happen to pick up that term from Jasun Horsley?
Vaccines have been quite effective at preventing cases of COVID-19 that lead to severe illness and death, but none has proved reliable at blocking transmission of the virus, Jones noted. Recent evidence has also made clear that the immunity provided by vaccines can wane in a matter of months.
The result is that even if vaccination were universal, the coronavirus would probably continue to spread.