Papers by Md. Abdullah Yusuf
Bangladesh Journal of Medical Microbiology, Jul 21, 2023
Background: Hepatitis B virus (HBV) related glomerulonephritis (GN) may be found in HBV seroposit... more Background: Hepatitis B virus (HBV) related glomerulonephritis (GN) may be found in HBV seropositive as well as seronegative patients. HBV may present in the renal tissue of such patients. Objective: The purpose of the present study was to assess status of HBsAg deposition in renal tissue among glomerulonephritis patients.
Indian military action within Pakistan, and during the global bipolarisation of the Cold War. The... more Indian military action within Pakistan, and during the global bipolarisation of the Cold War. These circumstances led to Pakistan and the United States pouring important resources into the Pakistani military. The consequence was the rapid growth of the military while civil institutions were left behind. In response to this and due to a fear of fractures within civil society being manipulated by foreign actors, Pakistan chose to take a centralised approach to its politics. These events, in combination with periods of direct military rule and Islamist influence, paved the way for the inequality of modern Pakistan's political and social landscape-not to mention the inherent democratic and constitutional weaknesses present today. Although these entrenched differences disadvantage almost all citizens within Pakistan, minority groups are by far the most marginalised. Pakistan's minority groups account for less than 5% of the population, and estimates suggest that Muslims make up between 95 and 97 percent of Pakistan's total population. Pakistan's founding father, Mohammed Ali Jinnah, outlined his vision for a tolerant Pakistan, which championed the equality of all citizens, in his famous speech on August 11, 1947. However, this vision remains to be realised. As the State inches towards Islam in its rhetoric in an attempt to add legitimacy to its rule, and as extremist Islamic groups gain ground, the marginalisation of and discrimination against minority groups looks set to increase. The situation looks grim for minority rights in Pakistan. A recent report has named Pakistan one of the most hostile nations for religious minorities. Obviously, issues such as these will
Journal of Current and Advance Medical Research, 2019
Background: Technology enhanced learning in medical curriculum is expanding rapidly because of re... more Background: Technology enhanced learning in medical curriculum is expanding rapidly because of research showing the benefits for learners in terms of engagement, convenience, attainment and enjoyment. Objectives: The purpose of the present study was to explore medical students’ perspective on technology enhanced learning in undergraduate pharmacology. Methodology: This descriptive cross-sectional study was conducted in the Faculty of Medicine during 2016 for a period of three (3) months. Second year MBBS students who were studying in the International Medical School, Management & Science University,Selangor, Malaysia with the age group of equal or more than 18 years of age with both sexes were selected as study population. Several online quizzes were conducted by Quizizz. Data were analysed after online quizzes using semi-structured questionnaire. Results: A total number of 42 students were involved in this study. Among these 35(83.33%) surveyed students were strongly agreed with ti...
Bangladesh Journal of Medical Microbiology, Dec 9, 2023
Presence of bacteria in urine along with physical symptoms is referred as UTI. One of the illness... more Presence of bacteria in urine along with physical symptoms is referred as UTI. One of the illnesses that still has a high mortality and morbidity rate, even after receiving numerous treatments and numerous antibiotics, is urinary tract infection 1. Because the urinary tract is typically free of bacteria, viruses, fungi, and parasites, infections there lead to urinary tract infections. Renal failure is the most fatal of its complications, according to Mandell et al 2. Bacteriuria refers to the presence of bacteria in the urine, which increases the risk of urinary tract infection. Urine analysis and urine culture should be used to confirm urinary tract infection. If the urine culture obtained by clean catch midstream has more than 100,000 colony units per mL or catheterization method has more than 100 colony units per ml, it is considered positive 2. Urinary infection is diagnosed if the patient has symptoms such as dysuria, urinary frequency, suprapubic pain, burning sensation during micturition with fever 1. Dipstick test like leukocyte
Bangladesh Journal of Medical Microbiology, Oct 9, 2023
Bangladesh journal of infectious diseases, Jul 25, 2023
Background: Blood culture is important for diagnosis of various diseases and isolation of microor... more Background: Blood culture is important for diagnosis of various diseases and isolation of microorganisms. Objective: The purpose of the present study was to assess the rapid detection of microorganisms by automated blood culture system. Methodology: This retrospective study was conducted in the
Bangladesh journal of infectious diseases, Jul 25, 2023
Background: Wound infection gaining utmost importance day by day because of emergence of drug res... more Background: Wound infection gaining utmost importance day by day because of emergence of drug resistant bacteria. Objective: This study was carried out to see the pattern of aerobic bacterial pathogens along with MRSA and ESBL producing strains causing wound infection. Methodology: This cross sectional study was conducted from May 2010 to April 2011. Wound swabs were taken from the patients suffering from wound infections admitted in the different surgical wards of Rajshahi Medical College Hospital, Rajshahi, Bangladesh. The study place was the
Journal of Dhaka Medical College, Nov 19, 2018
Background: Ovarian malignancy is one of the most common causes of cancer deaths in females in Ba... more Background: Ovarian malignancy is one of the most common causes of cancer deaths in females in Bangladesh. Due to poor early symptoms and lack of screening protocol, it is detected later in the clinical course of the disease. It is also one of the most treatable tumors because majorities are sensitive to chemo-radiation. An accurate histology is often a critical factor in achieving optimum treatment response. Objective: To study the frequency and histological patterns of neoplastic ovarian lesions. Methodology: A retrospective cross sectional study was done. We analyzed the data compiled from ovarian lesions biopsied and reported in a private diagnostic center from January 2008 to December 2015. Results: Out of 231 ovarian specimens only 66 were neoplastic lesions, while the rest were nonneoplastic cysts. The age range was 9 to 65 years with a mean of 36.58 ±10.45. 73 percent (48) were benign, 6.01 percent (4) were borderline and 21.21 percent (14) were malignant. Surface epithelial tumors were the most common ovarian neoplasm (n=48; 72.73%) followed by germ cell tumor (n=14; 21.21%) and sex cord stromal tumor (n=4; 6.01%). Serous cystadenoma was the commonest benign tumor (23) followed by dermoid cyst (11), and mucinous cystadenoma (10). Only 4 borderline malignant tumors were found; 03 of which were mucinous and 01 serous. The number of malignant tumor was 18. Malignant mucinous neoplasm was the commonest, in both invasive carcinoma (05) and borderline group (03). Conclusion: Benign ovarian neoplasm was more common than malignant ones. Surface epithelial tumor was the frequent group followed by germ cell tumor. Serous cystadenoma was most common among benign tumors whereas mucinous cystadenocarcinoma was the commonest malignant tumor.
Journal of current and advance medical research, Jun 20, 2018
Background: The prevalence of non-cardiac chest pain is estimated to be more than 65.0% of all ca... more Background: The prevalence of non-cardiac chest pain is estimated to be more than 65.0% of all cases with chest pain. Objective: The objective of the present study was to see the clinic-demographics characteristics and investigational findings of cervical spondylosis patients presented with chest pain. Methodology: This cross-sectional study was carried out in the department of Physical Medicine & Rehabilitation at National Institute of Cardiovascular Disease (NICVD), Dhaka, Bangladesh from July 2012 to June 2013 for a period of one year. The diagnosis was made by detailed history, clinical examination and relevant investigations. Result: In this study, female (60%) were much more sufferer especially in much younger age group (41.67%). People from urban area (68.75%) and affluent status (41.67%) were more affected; also who were in anxiety-depressed state of mind (50%) and those who worked by neck bending posture (45.83%). All patients presented with chest pain (100%) & other associated symptoms like arm pain (41.67%), tingling sensation of left upper limb (22.91%), shoulder pain (25.0%) and scapular pain (16.67%). All (100%) patients had normal ECG finding. On the other hand, they (100.0%) had some finding in cervical spine X-ray; clinically the patient had painful neck movement (75.0%). A specific test for cervical radiculopathy "spurling maneuver" was positive in (22.91%). Conclusion: Through chest pain due to cervical disc disease widely reported but remains under recognized. So careful evaluation of patient for chest pain might have saved the patient for admission and various expensive invasive procedure.
Journal of Science Foundation, May 25, 2015
Journal of Science Foundation, Aug 8, 2017
Background: The clinical characteristics of hepatocellular carcinoma are varied from person to pe... more Background: The clinical characteristics of hepatocellular carcinoma are varied from person to person. Objectives: The purpose of the present study was to see the clinical profiles of hepatocellular carcinoma patients. Methodology: This cross sectional study was carried out in the
Journal of National Institute of Neurosciences Bangladesh, Apr 6, 2017
Background: Leaf extract of Catharanthus roseus has medicinal effect. Objective: The purpose of t... more Background: Leaf extract of Catharanthus roseus has medicinal effect. Objective: The purpose of the present study was to compare the effect of leaf extract of Catharanthus roseus (Nayantara) with atorvastatin on serum lipid profile in fat-fed rats. Methodology: This was an experimental animal study carried out in the Department of Pharmacology and Therapeutics at Dhaka Medical College, Dhaka from July 2005 to June 2006 for a period of one year. Adult Long Evans rats of both sexes were used for the study. The rats were divided into seven groups designed as A, B, C, D, E, F and G. Each group was comprised of 8 rats which were treated for 10 days and were sacrificed on 11th day. The experiment were designed to demonstrate the effect of C. roseus on serum lipid profile in hyperlipidaemic rats and the hypolipidaemic effects were compared to a standard oral lipid lowering drug, atorvastatin. Result: A total number of 56 adult Long Evans rats of both sexes were used for the study. Here the effect of leaf extract of C. roseus at different doses on lipid level of fat-fed rats was observed which were compared with the hyperlipidaemic control group. In the same time the effect of Atorvastatin on serum lipid level were observed. The observed lipid lowering effect of leaf extract of C. roseus was evaluated biochemically by significant (p<0.001) decrease of serum total cholesterol (TCL), triglyceride (TG) and low density lipoprotein (LDL) levels. The leaf extract of C. roseus was given at three different doses daily in oral route for 10 days along with fatty diet and statistically significant (p<0.05) decrease was observed in all serum lipid parameter (TCL,TG, LDL) except high density lipoprotein (HDL). Which was more evident in higher doses treated group (1 ml/kg and 1.5 ml/kg). Atorvastatin reduced all three parameter (TCL, TG, &LDL) significantly (p<0.001). It increased HDL significantly high (p<0.001). Conclusion: The leaf extract of C. roseus is responsible for lipid lowering effect.
Bangladesh journal of infectious diseases, Apr 24, 2020
Background: The world is struggling to contain the novel coronavirus (COVID-19) outbreak and the ... more Background: The world is struggling to contain the novel coronavirus (COVID-19) outbreak and the healthcare infrastructure and testing capacity have emerged as major issues. Adequate testing capacity for SARS-CoV-2 is lacking worldwide, preventing people from accessing care. It also means the community is relying on models and estimates to get an accurate picture of the outbreak and its evolution, even though this information is critical to inform public health measures that could stop or slow diseases transmission. Different countries have implemented different testing strategies, reflecting the availability of diagnostics and reagents and the needs of the individual health systems. Objective: The purpose of the present study was to see the different laboratory tests for detection of SARS Cov2 from Covid19 patients. Methodology: We searched electronic databases like MEDLINE, EMBASE, CINAHL, and Science Citation Index, checked documents and references, and contacted experts. We included WHO reported Corona diseases (COVID-19) situation reports from January 2020 to April 10, 2020 related to the diagnosis of COVID-19 diseases. Both reviewers independently screened titles and abstracts, assessed studies for inclusion, appraised quality, and extracted data. Result: Regular confirmation of COVID-19 was based on the detection of particular sequences of viral RNA by NAAT such as Polymerase chain reaction (PCR). Sensitivity was comparatively high in the first week. Serological assays are qualitative detection of IgM and IgG antibodies against SARS-CoV-2 in serum gave result within 2 to 10 minutes. The rapid antigen tests might be providing the advantage of fast time to results and low cost detection of human CoVs, however they were likely to suffer from reduced sensitivity based on the experience with this method for other respiratory viruses. Conclusion: Immunological assays are never goanna be better than molecular ones. May be molecular and immunological tests combined can be a good strategy.
Bangladesh journal of infectious diseases, Aug 3, 2018
Background: The genus Enterococcus is of increasing significance as a cause of nosocomial infecti... more Background: The genus Enterococcus is of increasing significance as a cause of nosocomial infections and this trend is exacerbated by the development of antibiotic resistance. Objective: The aims of this study was to find out the susceptibility pattern and the prevalence of virulence genes in Enterococcus strains isolated from urinary tract infection in Bangladesh. Methodology: This cross-sectional study was conducted in the
Journal of National Institute of Neurosciences Bangladesh, Jan 15, 2023
DOAJ (DOAJ: Directory of Open Access Journals), Jul 1, 2015
Background: Lower respiratory tract infections (LRTIs) are the most frequent infections among pat... more Background: Lower respiratory tract infections (LRTIs) are the most frequent infections among patients in Intensive care units (ICUs). Aims: To know the bacterial profi le and determine the antibiotic susceptibility pattern of the lower respiratory tract isolates from patients admitted to the ICU. Settings and Design: Tertiary care hospital, retrospective study. Materials and Methods: Transtracheal or bronchial aspirates from 207 patients admitted to the ICU were cultured, identifi ed, and antibiotic sensitivity was performed by standard methods. Statistical Analysis Used: SPSS software was used for calculation of % R of 95% confi dence interval (CI). Results: Of 207 specimens, 144 (69.5%) were culture positive and 63 (30.4%) showed no growth. From 144 culture positives, 161 isolates were recovered, of which 154 (95.6%) were Gram negative bacilli (GNB). In 17 (11.0%) patients, two isolates per specimen were recovered. The most common GNB in order of frequency were Pseudomonas aeruginosa (35%), Acinetobacter baumannii (23.6%), and Klebsiella pneumoniae (13.6%). A very high rate of resistance (80-100%) was observed among predominant GNB to ciprofl oxacin, ceftazidime, co-trimoxazole, and amoxycillin/clavulanic acid combination. Least resistance was noted to meropenem and doxycycline. Conclusion: Nonfermenters are the most common etiological agents of LRTIs in ICU. There is an alarmingly high rate of resistance to cephalosporin and -lactam--lactamase inhibitor group of drugs. Meropenem was found to be the most sensitive drug against all GNB. Acinetobacter and Klebsiella spp. showed good sensitivity to doxycycline.
Journal of National Institute of Neurosciences Bangladesh, Dec 14, 2020
Background: Animal bite management are very crucial part in the post prophylaxis treatment. Objec... more Background: Animal bite management are very crucial part in the post prophylaxis treatment. Objective: The purpose of the present study was to see the demographic profile of animal bite cases at a dedicated anti-rabies hospital. Methodology: This retrospective chart review based on secondary data received from animal bite register was conducted in the
Bangladesh journal of infectious diseases, Jul 11, 2019
Chikungunya is a febrile illness which is usually self-limiting caused by Chikungunya virus (CHIK... more Chikungunya is a febrile illness which is usually self-limiting caused by Chikungunya virus (CHIKV). It is transmitted bythe bites of infected adult female mosquitoes mainly Aedesaegypti and Aedesalbopictus from human to human; these vectors also transmit other viral diseases including dengue, zika virus and yellow fever. These viral diseases presented in a similar manner in their early stage of infection specially dengue and chikungunya since neither of them possesses any specific feature to be distinguished clinically. Their outcome and treatment strategies are distinct so early and accurate diagnosis is mandatory for better management and taking appropriate measures to prevent or reduce severity of complications. An early confirmation of any infection demands diagnostic tools that are highly specific and cost effective. Currently no diagnostic tool is available for CHIKV detection which can fulfill these criteria. Moreover effective surveillance, outbreak control, vaccine design and drug development all this demand proper diagnosis. In this review we focus on limitation of available laboratory tests related to diagnosis of chikungunya virus and discuss priorities for further studies needed for disease diagnosis in early stage to control the outbreaks.
Journal of Shaheed Suhrawardy Medical College, Mar 7, 2017
Bangladesh journal of infectious diseases, Aug 4, 2018
Background: Surgical and burn wound infection are the most common infection in the hospital setti... more Background: Surgical and burn wound infection are the most common infection in the hospital settings. Objective: The aim of the present study was to see the status of extended spectrum beta-lactamase (ESBL) producing bacteria isolated from patients presented with surgical and burn wound infection. Methodology: This cross-sectional study was conducted in the Department of Microbiology, BSMMU from January to December 2006, at a period of one year. This study was carried out to detect extended spectrum βlactamase producing Gram negative bacteria rapidly by using a kit containing chromogenic cephalosporin directly from primary culture by comparison with phenotypic confirmatory method. Result: Total 181 samples were collected from patients with wound infections of which 170(93.9%) bacteria were isolated. Among individual samples ESBLs positive strains were highest in surgical wound which was 22(31.42%) and 24(28.24%) isolates respectively. From surgical wound swab ESBL was found 3(42.9%) isolates from Klebsiella species. ESBL producing E. coli was found in 12(35.3%) isolates. Pseudomonas species showed in 2(22.2%) isolates and 1(33.3%) isolate of Acinetobactor species. ESBL positive E. coli was found in 5(45.45%) isolates from burn wound. ESBL positive Proteus species was detected in 11(28.94%) isolates from burn wound. Conclusion: Most common bacteria isolated from the infected surgical and burn wound are E. coli and Proteus species, though Klebsiella species is the most common ESBL producing bacteria isolated from both infected surgical and burn wound.
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Papers by Md. Abdullah Yusuf