The data included the age at presentation, gender of the subjects, TNM staging, LN metastases bas... more The data included the age at presentation, gender of the subjects, TNM staging, LN metastases based on histopathological data, ER, PR, HER2 (HER2/neu), and MUC2 status. All the cases satisfying inclusion and exclusion criteria were included in the study.
Introduction: Mucinous Carcinoma (MC) is a special type of breast cancer. It comprises 4% (1-7%) ... more Introduction: Mucinous Carcinoma (MC) is a special type of breast cancer. It comprises 4% (1-7%) of all invasive breast cancer. MC is also called colloid breast cancer characterised by nests of cells floating in lakes of mucin. It is divided into two subtypes Pure Mucinous Carcinoma (PMC) and Mixed Mucinous Carcinoma (MMC). PMC classified into two main types according to its structural and cytological features type A (paucicellular) the classical variant with a large amount of extracellular mucin, and type B (hypercellular) a hypercellular variant with less mucin and often with neuroendocrine differentiation. Hormone receptors, Human Epidermal growth factor Receptor-2 (HER2) and MUC2 status play an important role in prognosis and management. Aim: To study histopathological features of MC breast and Immunohistochemical (IHC) status. Materials and Methods: A retrospective study of patients who presented with breast cancer were studied at Department of Pathology, Karnataka Institute of...
The data included the age at presentation, gender of the subjects, TNM staging, LN metastases bas... more The data included the age at presentation, gender of the subjects, TNM staging, LN metastases based on histopathological data, ER, PR, HER2 (HER2/neu), and MUC2 status. All the cases satisfying inclusion and exclusion criteria were included in the study.
Introduction: Mucinous Carcinoma (MC) is a special type of breast cancer. It comprises 4% (1-7%) ... more Introduction: Mucinous Carcinoma (MC) is a special type of breast cancer. It comprises 4% (1-7%) of all invasive breast cancer. MC is also called colloid breast cancer characterised by nests of cells floating in lakes of mucin. It is divided into two subtypes Pure Mucinous Carcinoma (PMC) and Mixed Mucinous Carcinoma (MMC). PMC classified into two main types according to its structural and cytological features type A (paucicellular) the classical variant with a large amount of extracellular mucin, and type B (hypercellular) a hypercellular variant with less mucin and often with neuroendocrine differentiation. Hormone receptors, Human Epidermal growth factor Receptor-2 (HER2) and MUC2 status play an important role in prognosis and management. Aim: To study histopathological features of MC breast and Immunohistochemical (IHC) status. Materials and Methods: A retrospective study of patients who presented with breast cancer were studied at Department of Pathology, Karnataka Institute of...
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