Impaction is when a tooth ceases to emerge into the dental arch, usually due to a lack of space o... more Impaction is when a tooth ceases to emerge into the dental arch, usually due to a lack of space or the presence of an entity preventing the tooth's path of eruption. Teeth rarely can erupt in an ectopic position or in a close proximity to the opposite side which are usually asymptomatic and can be impacted. 3 A 22-year-old female patient was referred to our department complaining of pain in the inferior region. On intraoral examination, right mandibular canine was seen to be reported.
Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease characterized by an extensiv... more Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease characterized by an extensive fibroinflammatory stroma, which includes abundant cancer-associated fibroblast (CAF) populations. PDAC CAFs are heterogeneous, but the nature of this heterogeneity is incompletely understood. The Hedgehog (HH) pathway functions in PDAC in a paracrine manner, with ligands secreted by cancer cells signaling to stromal cells in the microenvironment. Previous reports investigating the role of HH signaling in PDAC have been contradictory, with HH signaling alternately proposed to promote or restrict tumor growth. In light of the newly discovered CAF heterogeneity, we investigated how HH pathway inhibition reprograms the PDAC microenvironment. Experimental Design: We used a combination of pharmacologic inhibition, gain- and loss- of-function genetic experiments, CyTOF, and single cell RNA-sequencing to study the roles of HH signaling in PDAC. Results: We find that HH signaling is uniquely ac...
International Journal of Engineering and Techniques, 2020
Intrusion Detection System (IDS) is well-defined as a Device or software application which monito... more Intrusion Detection System (IDS) is well-defined as a Device or software application which monitors the system activities and finds if there is any malevolent activity that has occured. Unresolved growth and traditional use of internet raises anxieties about how to connect and protect the digital information securely. In today's world hackers use different types of attacks for getting the valued information. Many of the intrusion detection techniques, methods and procedures help to perceive those several attacks. The main objective of this paper is to provide a complete study about the intrusion detection, sorts of intrusion detection methods, types of attacks, diverse tools and practices, research needs, challenges and finally change the IDS Tool for Research Purpose That tool are capable of perceiving and prevent the attack from the intruder.
Impaction is when a tooth ceases to emerge into the dental arch, usually due to a lack of space o... more Impaction is when a tooth ceases to emerge into the dental arch, usually due to a lack of space or the presence of an entity preventing the tooth's path of eruption. Teeth rarely can erupt in an ectopic position or in a close proximity to the opposite side which are usually asymptomatic and can be impacted. 3 A 22-year-old female patient was referred to our department complaining of pain in the inferior region. On intraoral examination, right mandibular canine was seen to be reported.
Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease characterized by an extensiv... more Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease characterized by an extensive fibroinflammatory stroma, which includes abundant cancer-associated fibroblast (CAF) populations. PDAC CAFs are heterogeneous, but the nature of this heterogeneity is incompletely understood. The Hedgehog (HH) pathway functions in PDAC in a paracrine manner, with ligands secreted by cancer cells signaling to stromal cells in the microenvironment. Previous reports investigating the role of HH signaling in PDAC have been contradictory, with HH signaling alternately proposed to promote or restrict tumor growth. In light of the newly discovered CAF heterogeneity, we investigated how HH pathway inhibition reprograms the PDAC microenvironment. Experimental Design: We used a combination of pharmacologic inhibition, gain- and loss- of-function genetic experiments, CyTOF, and single cell RNA-sequencing to study the roles of HH signaling in PDAC. Results: We find that HH signaling is uniquely ac...
International Journal of Engineering and Techniques, 2020
Intrusion Detection System (IDS) is well-defined as a Device or software application which monito... more Intrusion Detection System (IDS) is well-defined as a Device or software application which monitors the system activities and finds if there is any malevolent activity that has occured. Unresolved growth and traditional use of internet raises anxieties about how to connect and protect the digital information securely. In today's world hackers use different types of attacks for getting the valued information. Many of the intrusion detection techniques, methods and procedures help to perceive those several attacks. The main objective of this paper is to provide a complete study about the intrusion detection, sorts of intrusion detection methods, types of attacks, diverse tools and practices, research needs, challenges and finally change the IDS Tool for Research Purpose That tool are capable of perceiving and prevent the attack from the intruder.
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Papers by Abhishek Doshi