The compartmental model for aluminium kinetics in human body of Nolte et al, as reparameterized by Weisser et al, implemented under mrgsolve and R.

Prediction of partition coefficient

Simplest mathematical model for drug concentration in blood plasma vs. time

Customisable pharmacokinetic model accessible via bash CLI allowing for variable dose calculations as well as intravenous and subcutaneous administration calculations

Raw R code used in manuscript: Hughes JH, Upton RN, Foster DJR. Comparison of non-compartmental and mixed effect modelling methods for establishing bioequivalence for the case of two compartment kinetics and censored concentrations. J Pharmacokinet Pharmacodyn. 2017:1-12.

Raw R code for manuscript: Hughes JH, Upton RN, Reuter SE, Rozewski DM, Phelps MA, Foster DJR. Development of a physiologically-based pharmacokinetic model for intravenous lenalidomide in mice.

가이드라인: 임상시험의 통계 원칙 - 식품의약품안전처 식품의약품안전평가원 의약품심사부 의약품심사조정과 https://pipetcpt.github.io/book-stat

Calcium Caffeine Model Simulations. Post-graduate work for Dr. Stephanie Reuter-Lange at University of South Australia.

Python project that simulates a Target Controlled Infusion pump for anesthesia delivery

A bunch of PK/PD patient models with various diseases for open-/closed-loop control systems

Raw R code used in manuscript: Hughes JH, Phelps MA, Upton RN, et al. Population pharmacokinetics of lenalidomide in patients with B-cell malignancies. Br J Clin Pharmacol. 2019;85(5):924-934.

Este repositorio se enfoca en automatizar la extracción y análisis de datos farmacocinéticos de diversas fuentes, con el fin de obtener una base de datos integral y estandarizada de información farmacocinética junto con los scripts de creación y análisis, dirigidos a resolver los retos de la individualización en farmacología actuales.

Dosing application for manuscript: Harris, B.D.W., Phan, V., Perera, V. et al. Inability of Current Dosing to Achieve Carboplatin Therapeutic Targets in People with Advanced Non-Small Cell Lung Cancer: Impact of Systemic Inflammation on Carboplatin Exposure and Clinical Outcomes. Clin Pharmacokinet (2020). https://doi.org/10.1007/s40262-020-00870-6

Simulate the absorption and elimination of drugs in real time using pharmacokinetic formulas.

💊 Conceptual custom GPT that simulates the pharmacokinetics and pharmacodynamics of drugs.

A modular inverse QSAR pipeline

😄 NonCompart 패키지를 사용해서 2x2 생동성시험의 분산분석 등을 손쉽게 해주는 패키지입니다. https://asancpt.github.io/ncarbe

Workflows for prediction of inhalation toxicokinetics from chemical structure including the individual steps in the training and optimization of QSPR models, model selection and prediction of partition coefficients, applicability domain and toxicokinetics profile.

Shiny App: tdm-cyclosporin https://pipet.shinyapps.io/cyclosporin/

Various apps of molim Inc.