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Registers of clinical trials that can be accessed with package ctrdata-package as of November 2022. The EU CTIS will be mandatory for sponsors from January 2023 and cannot yet supported by ctrdata.

Details

  • EUCTR: The European Union Clinical Trials Register contains almost 43,000 clinical trials (using one or more medicines as investigational medicinal product, IMP; in Europe and beyond)

  • CTGOV: ClinicalTrials.gov includes more than 430,000 interventional and observational studies (the beta website is not supported by package ctrdata)

  • ISRCTN: The ISRCTN Registry includes almost 23,000 interventional or observational health studies

MaterialEUCTRCTGOVISRCTN
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Glossarylinklinklink
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Expert / advanced searchlinklinklink
Example*linklinklink
DefinitionslinkProtocol, results, names, syntaxlink

*The example is an expert search that retrieves interventional trials with neonates, investigating infectious conditions: EUCTR retrieves trials with neonates, but not exclusively. The CTGOV expert search retrieves trials exclusively in neonates. ISRCTN retrieves a small number of studies. Thus, after loading trials with ctrLoadQueryIntoDb into a database collection, corresponding sets of trials need to be defined, based on values of fields of interest (e.g., eligibility.maximum_age from CTGOV and f115_children_211years from EUCTR), which can be obtained from the collection using dbGetFieldsIntoDf.

Author

Ralf Herold ralf.herold@mailbox.org