Computer based approach to recreate the continuous evolution in time and space of developmental stages from 3D volumetric images. This method uses the mathematical approach of spherical harmonics to re-map discrete shape data into a space in which facilitates a smooth interpolation over time.

This aproach was tested on mouse limb buds (from E10 to E12.5) and embryonic hearts (from 10 to 29 somites).

A key advantage of this method is that the resulting 4D trajectory takes advantage of all the available data, while also being able to interpolate well through time intervals for which there is little or no data.

For more information --> https://doi.org/10.1101/2021.12.16.472948

👤 Giovanni Dalmasso

• Website: https://tinyurl.com/yc6pbyb2
• Twitter: @giodalmasso
• Github: @gioda
• LinkedIn: @giovanni-dalmasso

👤 Marco Musy

• Website: https://tinyurl.com/3zy9zmmy
• Github: @marcomusy

Contributions, issues and feature requests are welcome!
Feel free to check issues page.

Give a ⭐️ if this project helped you!

Copyright © 2021 Giovanni Dalmasso.
This project is MIT licensed.