Obsoletion request: barbed-end actin filament capping (GO:0051016) actin filament capping (GO:0051693) pointed-end actin filament capping (GO:0051694)

[ValWood]

Please provide as much information as you can:

Follow on from #22594

pointed-end actin filament capping (GO:0051694)
barbed-end actin filament capping (GO:0051016)
actin filament capping (GO:0051693)

The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits. [ISBN:071673706X]

currently a child of regulation of actin polymerization

migrate annotations to NEW Molecular function terms where appropriate
GONEW actin filament cap activity
GONEW actin filament barbed end cap activity
GONEW actin filament pointed end cap activity

However note that there are erroneous annotations.

Formins should not have been annotated to
barbed-end actin filament capping (GO:0051016)
and should not be annotated to the new MF terms

because their purpose is not "preventing the addition, exchange or removal of further actin subunits"

• GO term ID and Label

• Reason for deprecation Put an x in the appropriate box:

• The reason for obsoletion is that the term is not clearly defined and usage has been inconsistent.
• The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
• The reason for obsoletion is that this term represent an assay and not a GO process.
• The reason for obsoletion is that this represents a phenotype.
• The reason for obsoletion is that the data from the paper for which the term was requested can be accurately described using [appropriate GO term].
• The reason for obsoletion is that this term represents a molecular function.
• The reason for obsoletion is that this term represents a gene product.
• The reason for obsoletion is that this term refers to a class of proteins.
• The reason for obsoletion is that this term was added in error.
• The reason for obsoletion is that more specific terms were created.
• The reason for obsoletion is that this term was an unnecessary grouping term.
• The reason for obsoletion is that the meaning of the term is ambiguous.
• The reason for obsoletion is that is not known to be catalyzed by any gene product.
• The reason for obsoletion is that it more specific than the specificity of any known gene product.
• The reason for obsoletion is that there is no evidence that this function/process/component exists.

• "Replace by" term (ID and label)
  If all annotations can safely be moved to that term

• "Consider" term(s) (ID and label)
  Suggestions for reannotation

• Are there annotations to this term?

• How many EXP:

• Are there mappings and cross references to this term? (InterPro, Keywords; check QuickGO cross-references section)

• Is this term in a subset? (check the AmiGO page for that term)

• Any other information

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Checklist for ontology editor

Check term usage and metadata in Protégé

• check term usage in the ontology
• check internal mappings: RHEA, EC, MetaCyc
• check subset usage
• check taxon constraints

Check annotations

• create Annotation Review spreadsheet
• • Annotation Review template: https://docs.google.com/spreadsheets/d/1izV3q1jnq_Ybg5MJ53O_b5BCTkGtjl_Fi-cOg3-7eBE/edit#gid=0
• • Instructions: https://wiki.geneontology.org/Annotation_Review_Request
• create annotation review ticket: https://github.com/geneontology/go-annotation/issues/new?assignees=&labels=annotation+review&template=annotation-review-for-obsoletion.md&title=Review+annotations+to+%5BINSERT+GO+TERM%5D
• find external mappings (via IEAS), include in obsoletion notice
• tag curators in Annotation Review ticket. Responsible annotator for each group: https://github.com/geneontology/go-site/blob/master/metadata/group-contacts.csv

Notification

• create obsoletion announcement
• announce to GO friends ([email protected])
• paste the text in the ontology ticket

[ValWood]

@pgaudet does this sound OK?

[ValWood]

from #19107
Is the correct solution to restore

GO:0003782
obsolete F-actin capping activity
?

[pgaudet]

It's certainly an option -
what process should these gees be annotated to? actin cytoskeleton organization?

[ValWood]

Current parentage:

[ValWood]

I'm a bit confused by the CC term "actin cap"

GO:0030478 actin cap
Polarized accumulation of cytoskeletal proteins (including F-actin) and regulatory proteins in a cell.
?

[ValWood]

ignore. This CC "actin cap" is unrelated to "actin capping"