Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

Sign up for GitHub

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Jump to bottom

Support for SEQUEL I or II #20

Open
fanggang opened this issue Feb 9, 2022 · 2 comments
Open

Support for SEQUEL I or II #20

fanggang opened this issue Feb 9, 2022 · 2 comments

Comments

@fanggang
Copy link
Contributor

fanggang commented Feb 9, 2022

No description provided.

@fanggang
Copy link
Contributor Author

fanggang commented Feb 9, 2022

mbin was initially developed for PacBio RS II data. Currently it does not support bam files in the Sequel system yet. We do plan to support Sequel data in the near future, and will make sure to update as soon as an update is available. In the meantime, for assembled contigs with relatively large size, say >500K, standard methylation motif discovery is supported in SMRTLink (separately for different contigs). This is not recommended for relatively small contigs. Sorry for the inconvenience, we will try to support bam files ASAP.

@fanggang
Copy link
Contributor Author

fanggang commented Feb 9, 2022

Users with access to nanopore sequencing may also consider using our other tool for methylation discovery and methylation binning: https://github.com/fanglab/nanodisco.

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Assignees
No one assigned
Labels
None yet
Projects
None yet
Milestone
No milestone
Development

No branches or pull requests
1 participant
@fanggang