diff --git a/Library/Formula/pyqt5.rb b/Library/Formula/pyqt5.rb
new file mode 100644
index 000000000000..e1f1562100db
--- /dev/null
+++ b/Library/Formula/pyqt5.rb
@@ -0,0 +1,72 @@
+require 'formula'
+
+class Pyqt5 < Formula
+  homepage 'http://www.riverbankcomputing.co.uk/software/pyqt/download5'
+  url 'http://downloads.sf.net/project/pyqt/PyQt5/PyQt-5.0/PyQt-gpl-5.0.tar.gz'
+  sha1 'ad143f8c1287e80f37db23618c9560b00f89bc60'
+
+  option 'enable-debug', "Build with debug symbols"
+
+  depends_on :python3 => :recommended
+  depends_on :python2 => :optional
+
+  depends_on 'qt5'
+
+  if build.with? 'python3'
+    depends_on 'sip' => 'with-python3'
+  else
+    depends_on 'sip'
+  end
+
+  def install
+    python do
+      args = [ "--confirm-license",
+               "--bindir=#{bin}",
+               "--destdir=#{lib}/#{python.xy}/site-packages",
+               # To avoid conflicst with PyQt (for Qt4):
+               "--sipdir=#{share}/sip#{python.if3then3}/Qt5/",
+               # sip.h could not be found automatically
+               "--sip-incdir=#{Formula.factory('sip').opt_prefix}/include" ]
+      args << '--debug' if build.include? 'enable-debug'
+
+      system python, "./configure.py", *args
+      system "make"
+      system "make", "install"
+      system "make", "clean"  # because this python block may be run twice
+
+      # For PyQt5 we default to put 3.x bindings in bin, unless --without-python3
+      if build.with? 'python3' and build.with? 'python'
+        ['pyuic5', 'pyrcc5', 'pylupdate5'].each { |f| mv(bin/f, bin/"#{f}-py2")}
+      end
+    end
+  end
+
+  def caveats
+    python.standard_caveats if python
+  end
+
+  test do
+    python do
+      (testpath/'test.py').write <<-EOS.undent
+        import sys
+        from PyQt5 import QtGui, QtCore, QtWidgets
+
+        class Test(QtWidgets.QWidget):
+            def __init__(self, parent=None):
+                QtWidgets.QWidget.__init__(self, parent)
+                self.setGeometry(300, 300, 400, 150)
+                self.setWindowTitle('Homebrew')
+                QtWidgets.QLabel("Python #{python.version} working with PyQt5. Quitting now...", self).move(50, 50)
+                QtCore.QTimer.singleShot(2500, QtWidgets.qApp.quit)
+
+        app = QtWidgets.QApplication([])
+        window = Test()
+        window.show()
+        sys.exit(app.exec_())
+      EOS
+
+      system "python#{python.if3then3}", "test.py"
+      rm testpath/'test.py'
+    end
+  end
+end