New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

Sign up for GitHub

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

LinDA Unusual p-value Distribution #54

Open

DarioS opened this issue May 29, 2024 · 0 comments

DarioS commented May 29, 2024

Using the data set shared previously via e-mail and fitting

adjNormalCancerFit <- linda(bacteriaMatrix, clinicalTablePairs, "~ Age * `Tissue Type` + Smoking * `Tissue Type` +
                            Gender * `Tissue Type` + `Primary Site` + (1|Patient)", "proportion", is.winsor = FALSE)

I get a strange-looking p-value distribution for many of the coefficients. For example,

How can it be made to be more uniform, as expected by statistics theory?

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment