diff --git a/ykman/_cli/config.py b/ykman/_cli/config.py
index 322fe892..d31527c4 100644
--- a/ykman/_cli/config.py
+++ b/ykman/_cli/config.py
@@ -35,7 +35,6 @@
     CAPABILITY,
     USB_INTERFACE,
     DEVICE_FLAG,
-    FORM_FACTOR,
     Mode,
 )
 from .util import (
@@ -123,15 +122,17 @@ def reset(ctx, force):
     This action will wipe all data and restore factory settings for
     all applications on the YubiKey.
     """
-    transport = ctx.obj["device"].transport
     info = ctx.obj["info"]
-    is_bio = info.form_factor in (FORM_FACTOR.USB_A_BIO, FORM_FACTOR.USB_C_BIO)
-    has_piv = CAPABILITY.PIV in info.supported_capabilities.get(transport)
-    if not (is_bio and has_piv):
-        raise CliFail(
-            "Full device reset is not supported on this YubiKey, "
-            "refer to reset commands for specific applications instead."
-        )
+    # reset_blocked is a sure indicator of the command
+    if not info.reset_blocked:
+        # No reset blocked, we can still check for Bio MPE
+        transport = ctx.obj["device"].transport
+        has_piv = CAPABILITY.PIV in info.supported_capabilities.get(transport)
+        if not (info._is_bio and has_piv):
+            raise CliFail(
+                "Full device reset is not supported on this YubiKey, "
+                "refer to reset commands for specific applications instead."
+            )
 
     force or click.confirm(
         "WARNING! This will delete all stored data and restore factory "
@@ -250,6 +251,14 @@ def _configure_applications(
     force,
 ):
     info = ctx.obj["info"]
+
+    # If any app reset is blocked, we will not be able to toggle applications
+    if info.reset_blocked:
+        raise CliFail(
+            "This YubiKey must be in a newly reset state before applications can be "
+            "toggled."
+        )
+
     supported = info.supported_capabilities.get(transport)
     enabled = info.config.enabled_capabilities.get(transport)
 
diff --git a/ykman/_cli/piv.py b/ykman/_cli/piv.py
index f7ea8e8b..8b47ee81 100644
--- a/ykman/_cli/piv.py
+++ b/ykman/_cli/piv.py
@@ -287,6 +287,12 @@ def set_pin_retries(ctx, management_key, pin, pin_retries, puk_retries, force):
                 "Retry attempts must be set before PIN/PUK have been changed."
             )
 
+    try:  # Can't change retries on Bio MPE
+        session.get_bio_metadata()
+        raise CliFail("PIN/PUK retries cannot be changed on this YubiKey.")
+    except NotSupportedError:
+        pass
+
     _ensure_authenticated(
         ctx, pin, management_key, require_pin_and_key=True, no_prompt=force
     )
@@ -304,7 +310,7 @@ def set_pin_retries(ctx, management_key, pin, pin_retries, puk_retries, force):
         click.echo("\tPIN:\t123456")
         click.echo("\tPUK:\t12345678")
     except Exception:
-        raise CliFail("Setting pin retries failed.")
+        raise CliFail("Setting PIN retries failed.")
 
 
 def _do_change_pin_puk(pin_complexity, name, current, new, fn):
@@ -347,6 +353,9 @@ def change_pin(ctx, pin, new_pin):
     info = ctx.obj["info"]
     session = ctx.obj["session"]
 
+    if not session.get_pin_attempts():
+        raise CliFail("PIN is blocked.")
+
     if not pin:
         pin = _prompt_pin("Enter the current PIN")
     if not new_pin:
@@ -382,6 +391,12 @@ def change_puk(ctx, puk, new_puk):
     info = ctx.obj["info"]
     session = ctx.obj["session"]
 
+    try:
+        if not session.get_puk_metadata().attempts_remaining:
+            raise CliFail("PUK is blocked.")
+    except NotSupportedError:
+        pass
+
     if not puk:
         puk = _prompt_pin("Enter the current PUK")
     if not new_puk:
diff --git a/ykman/piv.py b/ykman/piv.py
index a0df6dcb..632dad7e 100644
--- a/ykman/piv.py
+++ b/ykman/piv.py
@@ -526,22 +526,8 @@ def get_piv_info(session: PivSession):
         tries = session.get_pin_attempts()
         tries_str = "15 or more" if tries == 15 else str(tries)
     info["PIN tries remaining"] = tries_str
-    try:
-        puk_data = session.get_puk_metadata()
-        if puk_data.attempts_remaining == 0:
-            lines.append("PUK is blocked")
-        elif puk_data.default_value:
-            lines.append("WARNING: Using default PUK!")
-        tries_str = "%d/%d" % (
-            puk_data.attempts_remaining,
-            puk_data.total_attempts,
-        )
-        info["PUK tries remaining"] = tries_str
-    except NotSupportedError:
-        if pivman.puk_blocked:
-            lines.append("PUK is blocked")
 
-    try:
+    try:  # Bio metadata
         bio = session.get_bio_metadata()
         if bio.configured:
             info[
@@ -550,7 +536,21 @@ def get_piv_info(session: PivSession):
         else:
             info["Biometrics"] = "Not configured"
     except NotSupportedError:
-        pass
+        try:  # PUK metadata (on non-bio)
+            puk_data = session.get_puk_metadata()
+            if puk_data.attempts_remaining == 0:
+                lines.append("PUK is blocked")
+            elif puk_data.default_value:
+                lines.append("WARNING: Using default PUK!")
+            tries_str = "%d/%d" % (
+                puk_data.attempts_remaining,
+                puk_data.total_attempts,
+            )
+            info["PUK tries remaining"] = tries_str
+        except NotSupportedError:
+            # YK < 5.3
+            if pivman.puk_blocked:
+                lines.append("PUK is blocked")
 
     try:
         metadata = session.get_management_key_metadata()