This project automates the generation of the liver digital twin given parenchyma and vessels 3D models as input.

The digital twin is built in top of a Biomechanical model, which reflects the mechanical behavior of the organ. Liver and its internal structures is considered as an heteregeneous domain respecting different mechanical properties, such as anisotropy and incompressibility.

In this project, we consider parenchyma and vessels as two different biomechanical with different properties, then we mechanically couple both in both directions.

Vessels are processed as set of beams, each modeled as a Finite Element Model. The processing includes centerlines extraction, bezier curves fitting and regulare points sampling as shown in the following image.

Parenchyma domain is meshed with hexahedron elements and modeled using a Finite element model using a Hyperelastic material, see image bellow.

git clone ...
python3 DigitalTwin.py

python3 unittests/unittest_skeletonization.py
python3 unittests/unittest_bezier_fitting.py
python3 unittests/unittest_quaternion_extraction.py
python3 unittests/unittest_vessel_mechanical_modeling.py

Pull requests are welcome. For major changes, please open an issue first to discuss what you would like to change.

Please make sure to update tests as appropriate.

MIT