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Latest comment: 4 years ago by Pashley in topic Climate change

see also: Talk:Dengue fever/Archive

Dengue vaccine

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According to our sister project, there is a lot of research into a vaccine against Dengue and some of them have apparently yielded a product that is effective in humans. We should monitor this and update our article accordingly. Hobbitschuster (talk) 23:30, 15 January 2016 (UTC)Reply

This is very exciting! Mosquitoes love my girlfriend's blood, so I could not in good conscience take her to a country with endemic dengue like Malaysia as long as there was no good prophylaxis against dengue. If it'll be as simple as getting a vaccine, I'll be able to take her there in due course! Ikan Kekek (talk) 04:47, 16 January 2016 (UTC
According to reports I have seen, one vaccine exists now & several others are being worked on. The French company with the working one are "flipping the model", getting it approved first where it is most needed Mexico, Thailand, Brazil, ... rather than first in US & Europe. Pashley (talk) 04:32, 24 January 2016 (UTC)Reply
I have updated the article, but it will need monitoring & further updates later. Pashley (talk) 13:54, 24 January 2016 (UTC)Reply
Sanofi-Pasteur's web site says they got their first Asian approval in the Philippines in December. I asked a doctor (Filipino infectious disease specialist) about it today & he thought it would be available in March. Pashley (talk) 16:00, 28 January 2016 (UTC)Reply
A couple of news reports ; it is being deployed in the Philippines. Pashley (talk) 19:40, 9 May 2016 (UTC)Reply
Thanks for the update. Let's hope it will prove its effectiveness. Hobbitschuster (talk) 19:54, 9 May 2016 (UTC)Reply
A clinic in a Dumaguete shopping area offers it for ₱5000 (about US$100) for each of the three shots. Pashley (talk) 11:26, 27 November 2016 (UTC)Reply
w:Dengue_fever#Vaccine mentions approval in several other countries & says US$207 for the three shots in Indonesia. Pashley (talk) 05:17, 2 December 2016 (UTC)Reply
Any indications on effectiveness? Ikan Kekek (talk) 05:43, 2 December 2016 (UTC)Reply
WP has some info. Pashley (talk) 07:46, 2 December 2016 (UTC)Reply
Expensive, and mediocre protection, but better than nothing. Who can afford those kinds of prices in the Philippines and Indonesia? Ikan Kekek (talk) 08:05, 2 December 2016 (UTC)Reply
In the Philippines there is a pilot program giving it free to some fairly large number of school children and a plan to do all the country's kids if pilot results are good. The ₱5000 is at a downtown clinic; I plan to check at a hospital & will report what I find.
For some travellers, age may be a problem. I believe it is only approved for ages 9-45. I'll see what a doctor here says & report that too. Pashley (talk) 14:34, 2 December 2016 (UTC)Reply
Given that my girlfriend will be turning 46 early next year, that's an issue. Thanks for checking. Ikan Kekek (talk) 22:03, 2 December 2016 (UTC)Reply
Watsons are a chain of pharmacies with locations across SE Asia. Their Philippine stores now offer vaccination for ₱4000 (about US$80) for each of the three shots. The pharmacist I talked to thought there was no upper age limit. Pashley (talk) 23:36, 23 April 2017 (UTC)Reply
Thanks for the update. Has the vaccine's effectiveness improved? Ikan Kekek (talk) 00:20, 24 April 2017 (UTC)Reply
I'm neither a doctor nor a biologist & I have not read the research, so I'm utterly unqualified to comment on effectiveness. Ask a doctor, preferably a specialist. Pashley (talk) 01:11, 24 April 2017 (UTC)Reply

"Two studies of a vaccine found it was 60% effective and prevented more than 80 to 90% of severe cases.[54][55] This is less than wished for by some.[56]" So it is okay but not excellent. This is the most comprehensive review I have seen Travel Doc James (talk · contribs · email) 03:49, 24 April 2017 (UTC)Reply

Thanks a lot, Doc. I hope that by the time my girlfriend and I go (back for me) to Southeast Asia, more progress will have been made. Ikan Kekek (talk) 05:55, 24 April 2017 (UTC)Reply
It is getting complicated. The Philippines have withdrawn their approval of the vaccine and Sanofi restricts dengue vaccine "to limit its use to people who have had previous exposure to dengue virus". Pashley (talk) 11:44, 30 December 2017 (UTC)Reply
Philippine gov't have now re-approved it, not sure with what (if any) restrictions. Doc I spoke to did not recommend it for me, in my 70s & not in a high-risk area. Pashley (talk) 06:38, 15 November 2019 (UTC)Reply

Hawaii

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Hawaii's Big Island declares emergency over dengue fever infections, Reuters, Feb 9. Pashley (talk) 10:12, 12 February 2016 (UTC)Reply

Hawaii Declares State of Emergency over Zika, Dengue Pashley (talk) 14:20, 15 May 2016 (UTC)Reply

Caribbean

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Dengue fever is spreading in the Caribbean, and survivors say travellers aren't being warned Pashley (talk) 23:08, 21 February 2020 (UTC)Reply

Climate change

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Climate change accelerating the spread of disease-carrying mosquitoes, specifically aedes aegypti which are the main ones for dengue, Zika, ... Pashley (talk) 11:12, 11 May 2020 (UTC)Reply