Pronethalol

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Pronethalol (ICI-38174, Nethalide) was an early non-selective beta blocker clinical candidate. It was never used clinically due to carcinogenicity in mice.[1]

Pronethalol
Names
IUPAC name
2-(isopropylamino)-1-(2-naphthyl)ethanol
Identifiers
3D model (JSmol)
MeSH Pronethalol
  • CC(C)NCC(C1=CC2=CC=CC=C2C=C1)O
Properties
C15H19NO
Molar mass 229.31746
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

References

  1. ^ Stapleton MP (1997). "Sir James Black and propranolol. The role of the basic sciences in the history of cardiovascular pharmacology". Tex Heart Inst J. 24 (4): 336–42. PMC 325477. PMID 9456487.