Pronethalol

Pronethalol
Names
	IUPAC name 2-(isopropylamino)-1-(2-naphthyl)ethanol
Identifiers
CAS Number	54-80-8;
3D model (JSmol)	Interactive image;
MeSH	Pronethalol
PubChem CID	4930;
CompTox Dashboard (EPA)	DTXSID8021193 ;
	SMILES CC(C)NCC(C1=CC2=CC=CC=C2C=C1)O;
Properties
Chemical formula	C15H19NO
Molar mass	229.31746
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Pronethalol (codenamed ICI 38174 and also known as nethalide) was an early beta blocker clinical candidate. It was never used clinically due to carcinogenicity in mice.^[1]

References

^ Stapleton MP (1997). "Sir James Black and propranolol. The role of the basic sciences in the history of cardiovascular pharmacology". Tex Heart Inst J. 24 (4): 336–42. PMC 325477. PMID 9456487.

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[1] Stapleton MP (1997). "Sir James Black and propranolol. The role of the basic sciences in the history of cardiovascular pharmacology". Tex Heart Inst J. 24 (4): 336–42. PMC 325477. PMID 9456487.

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