EP 2619177 A1 20130731 - MATRIX METALLOPROTEINASE INHIBITORS
Title (en)
MATRIX METALLOPROTEINASE INHIBITORS
Title (de)
MATRIX-METALLOPROTEINASEINHIBITOREN
Title (fr)
INHIBITEURS DES MÉTALLOPROTÉINASES MATRICIELLES
Publication
Application
Priority
- IN 2278DE2010 A 20100924
- IB 2011054228 W 20110926
Abstract (en)
[origin: WO2012038943A1] The present invention relates to certain sulfone acetic acid derivatives of formula I as MMP inhibitor and processes for its syntheses. The invention also relates to pharmacological compositions containing the compounds of the present invention and methods of treating asthma, rheumatoid arthritis, COPD, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis, pulmonary inflammation, acute respiratory distress syndrome, perodontitis, multiple scleorisis, gingivitis, atherosclerosis, dry eye, neointimal proliferation which leads to restenosis and ischemic heart failure, stroke, renal disease, tumor metastasis, and other inflammatory disorders characterized by over expression and over activation of a matrix metalloproteinase using the compounds.
IPC 8 full level
C07C 309/60 (2006.01); A61K 31/192 (2006.01); A61K 31/325 (2006.01); A61P 11/00 (2006.01); A61P 19/02 (2006.01); A61P 35/00 (2006.01); C07C 321/28 (2006.01); C07C 333/08 (2006.01)
CPC (source: EP KR)
A61K 31/192 (2013.01 - KR); A61K 31/325 (2013.01 - KR); A61P 1/02 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 11/00 (2017.12 - EP); A61P 11/02 (2017.12 - EP); A61P 11/06 (2017.12 - EP); A61P 13/12 (2017.12 - EP); A61P 17/06 (2017.12 - EP); A61P 19/02 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 27/04 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 35/04 (2017.12 - EP); A61P 37/00 (2017.12 - EP); C07C 309/60 (2013.01 - KR); C07C 317/46 (2013.01 - EP); C07C 321/28 (2013.01 - KR); C07C 323/52 (2013.01 - EP); C07C 323/60 (2013.01 - EP); C07C 333/08 (2013.01 - KR)
Citation (search report)
See references of WO 2012038943A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2012038943 A1 20120329; AU 2011306397 A1 20130502; BR 112013006929 A2 20160712; CA 2812361 A1 20120329; CN 103221386 A 20130724; EA 201390405 A1 20140530; EP 2619177 A1 20130731; JP 2013538820 A 20131017; KR 20130137174 A 20131216; MX 2013003360 A 20130605; SG 188644 A1 20130531
DOCDB simple family (application)
IB 2011054228 W 20110926; AU 2011306397 A 20110926; BR 112013006929 A 20110926; CA 2812361 A 20110926; CN 201180056417 A 20110926; EA 201390405 A 20110926; EP 11776884 A 20110926; JP 2013529762 A 20110926; KR 20137010202 A 20110926