EP 1615697 A2 20060118 - NEW PYRAZOLO[1,5-A] PYRIMIDINE DERIVATIVES AND PHARMACEUTICAL USE THEREOF
Title (en)
NEW PYRAZOLO[1,5-A] PYRIMIDINE DERIVATIVES AND PHARMACEUTICAL USE THEREOF
Title (de)
NEUE PYRAZOLO[1,5-A] PYRIMIDIN-DERIVATE UND DEREN PHARMAZEUTISCHE VERWENDUNGEN
Title (fr)
UTILISATION PHARMACEUTIQUE DE PYRAZOLO[1,5-A] PYRIMIDINES SUBSTITUEES
Publication
Application
Priority
- DK 2004000253 W 20040406
- DK PA200300569 A 20030411
- US 46745303 P 20030502
Abstract (en)
[origin: WO2004089471A2] The use of substituted pyrazolo[1,5-a]pyrimidines for modulating the activity of 11beta-hydroxysteroid dehydrogenase type 1 (11betaHSD1) and the use of these compounds as phar-maceutical compositions are described. Also a novel class of substituted pyrazolo[1,5-a]pyrimidines their use in therapy, pharmaceutical compositions comprising the compounds, as well as their use in the manufacture of medicaments are described The present com-pounds are modulators and more specifically inhibitors of the activity of 11betaHSD1 and may be useful in the treatment, prevention and/or prophylaxis of a range of medical disorders where a decreased intracellular concentration of active glucocorticoid is desirable.
IPC 1-7
IPC 8 full level
A61K 31/519 (2006.01); A61K 45/06 (2006.01); A61P 3/04 (2006.01)
CPC (source: EP)
A61K 31/519 (2013.01); A61K 45/06 (2013.01); A61P 3/00 (2017.12); A61P 3/04 (2017.12); A61P 3/06 (2017.12); A61P 3/10 (2017.12); A61P 9/00 (2017.12); A61P 9/10 (2017.12); A61P 9/12 (2017.12); A61P 25/00 (2017.12); A61P 43/00 (2017.12)
Citation (search report)
See references of WO 2004089471A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004089471 A2 20041021; WO 2004089471 A3 20041223; EP 1615697 A2 20060118; JP 2006522749 A 20061005
DOCDB simple family (application)
DK 2004000253 W 20040406; EP 04725889 A 20040406; JP 2006504356 A 20040406