Friday, September 25, 2015

THE URINARY SYSTEM

also known as the renal system, consists of the kidneys, ureters, bladder, and the urethra. Each kidney consists of millions of functional units called nephrons. The purpose of the renal system is to eliminate wastes from the body, regulate blood volume and blood pressure, control levels of electrolytes and metabolites, and regulate blood ph. The kidneys have extensive blood supply via the renal arteries which leave the kidneys via the renal vein. Following filtration of blood and further processing, wastes (in the form of urine) exit the kidney via the ureters, tubes made of smooth muscle fibre’s that propel urine towards the urinary bladder, where it is stored and subsequently expelled from the body by urination (voiding). The female and male urinary systems are very similar, differing only in the length of the urethra. Urine is formed in the kidneys through a filtration of blood. The urine is then passed through the ureters to the bladder, where it is stored. During urination, the urine is passed from the bladder through the urethra to the outside of the body.
800-2000 millilitres (mL) of urine are normally produced every day in a healthy human. This amount varies according to fluid intake and kidney function.


There are several functions of the Urinary System:
·         Removal of waste product from the body (mainly urea and uric acid)
·         Regulation of electrolyte balance (e.g. sodiumpotassium and calcium)
·         Regulation of acid-base homeostasis
·         Controlling blood volume and maintaining blood pressure




     KIDNEYS-are bean-shaped organs that serve several essential regulatory roles in vertebrates. They remove excess organic molecules from the blood, and it is by this action that their best-known function is performed: the removal of waste products of metabolism. Kidneys are essential to the urinary system and also serve homeostatic functions such as the regulation of electrolytes, maintenance of acid–base balance, and regulation of blood pressure (via maintaining the salt and water balance). They serve the body as a natural filter of the blood, and remove water-soluble wastes which are diverted to the bladder. In producing urine, the kidneys excrete wastes such as urea and ammonium. They are also responsible for the reabsorption of water, glucose, and amino acids. The kidneys also produce hormones including calcitriol and erythropoietin. An important enzyme renin is also produced in the kidney which acts in negative feedback.
Located at the rear of the abdominal cavity in the retroperitoneal space, the kidneys receive blood from the paired renal arteries, and drain into the paired renal veins. Each kidney excretes urine into a ureter which empties into the bladder.
Renal physiology is the study of kidney function, while nephrology is the medical specialty concerned with kidney diseases. Diseases of the kidney are diverse, but individuals with kidney disease frequently display characteristic clinical features. Common clinical conditions involving the kidney include the nephritic and nephrotic syndromes, renal cysts, acute kidney injury, chronic kidney disease, urinary tract infection, nephrolithiasis, and urinary tract obstruction. Various cancers of the kidney exist. The most common adult renal cancer is renal cell carcinoma. Cancers, cysts, and some other renal conditions can be managed with removal of the kidney. This is known as nephrectomy. When renal function, measured by the glomerular filtration rate, is persistently poor, dialysis and kidney transplantation may be treatment options. Although they are not normally harmful, kidney stones can be extremely painful.




URETERS-In human anatomy, the ureters are tubes made of smooth muscle fibre’s that propel urine from the kidneys to the urinary bladder. In the adult, the ureters are usually 25–30 cm (10–12 in) long and ~3–4 mm in diameter. Histologically, the ureter contains transitional epithelium and an additional smooth muscle layer in the more distal one-third to assist with peristalsis. The ureters are a component of the urinary system. Urine, produced by the kidneys, travels along the ureters to the bladder.



URINARY BLADDER is the organ that collects urine excreted by the kidneys before disposal by urination. A hollow muscular, and distensible (or elastic) organ, the bladder sits on the pelvic floor. Urine enters the bladder via the ureters and exits via the urethra. There is no exact measurement for the volume of the human bladder, but different sources mention 500 mL (~17 oz.) to 1000 mL (~34 oz.). Urine, excreted by the kidneys, collects in the bladder before disposal by urination. The urinary bladder usually holds 300-350 ml of urine. As urine accumulates, the rugae flatten and the wall of the bladder thins as it stretches, allowing the bladder to store larger amounts of urine without a significant rise in internal pressure.


URETHRA- In anatomy, the urethra is a tube that connects the urinary bladder to the urinary meatus for the removal of fluids from the body. In male placental mammals, the urethra travels through the penis, and carries semen as well as urine. In female placental mammals, the urethra is shorter and emerges at the female external urethral orifice above the vaginal opening. Female placental mammals use their urethra only for urinating, but male placental mammals use their urethra for both urination and ejaculation. The external urethral sphincter is a striated muscle that allows voluntary control over urination.



NEPHRON- is the basic structural and functional unit of the kidney. Its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood, reabsorbing what is needed and excreting the rest as urine. A nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood ph. Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone, and parathyroid hormone. In humans, a normal kidney contains 800,000 to 1.5 million nephrons.

PREPARED BY: ALLEN DALE Q. VELACRUZ MW 2:30-4:00

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